Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ellen van Wijngaarden"'
Autor:
Christine E. Harper, Wenyao Zhang, Junsung Lee, Jung-Ho Shin, Megan R. Keller, Ellen van Wijngaarden, Emily Chou, Zhaohong Wang, Tobias Dörr, Peng Chen, Christopher J. Hernandez
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Mechanosensitive mechanisms are often used to sense damage to tissue structure, stimulating matrix synthesis and repair. While this kind of mechanoregulatory process is well recognized in eukaryotic systems, it is not known whether such a pr
Externí odkaz:
https://doaj.org/article/55c378c485e9407bae72177b781bbc90
Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play essential roles in purinergic signaling in the nervous system. Several studies suggest a link between Panx1-based channels activity and neurodegenerative disorders including Parkinson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d04acbe02f1a1e754256b67ea757c18
https://doi.org/10.22541/au.167109848.86499277/v1
https://doi.org/10.22541/au.167109848.86499277/v1
Multi-phenotypic screening of multiple zebrafish larvae plays an important role in enhancing the quality and speed of biological assays. Many microfluidic platforms have been presented for zebrafish phenotypic assays, but multi-organ screening of mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06e12a99639627c694b1117aafef75c
https://doi.org/10.22541/au.165346210.08721516/v1
https://doi.org/10.22541/au.165346210.08721516/v1
Publikováno v:
Integrative Biology. 12:211-220
Multi-phenotypic screening of zebrafish larvae, such as monitoring the heart and tail activities, is important in biological assays. Microfluidic devices have been developed for zebrafish phenotypic assays, but simultaneous lateral–dorsal screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ed70cf0a51becb82d704082a0e67de
https://doi.org/10.1093/intbio/zyaa016
https://doi.org/10.1093/intbio/zyaa016
Publikováno v:
Biotechnology journalREFERENCES. 17(6)
Electrical stimulation of brain or muscle activities has gained attention for studying the molecular and cellular mechanisms involved in electric-induced responses. We recently showed zebrafish's response to electricity. Here, we hypothesized that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9be66f10f5f40d373ec097107a76699
https://pubmed.ncbi.nlm.nih.gov/35332995
https://pubmed.ncbi.nlm.nih.gov/35332995
The signaling molecular mechanisms in zebrafish response to electricity are unknown, so here we asked if changes to dopaminergic signaling pathways can affect their electrically-evoked locomotion. To answer this question, the effects of multiple sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c2acfd1f84346fe591343e356476015
https://doi.org/10.22541/au.163458135.54745545/v1
https://doi.org/10.22541/au.163458135.54745545/v1
We previously showed that electric current can cause zebrafish larvae to move towards the anode pole along a microchannel. For a semi-mobile larva, we observed that zebrafish response to electricity depended on the current magnitude. The effects of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33becbeb6aa344f9d8794530c2516d53
https://doi.org/10.22541/au.163250768.83291245/v1
https://doi.org/10.22541/au.163250768.83291245/v1
Autor:
Hannah Yorke Gambhir, Ria Shah, Roshan Roy, Neeha Rahman, Marina Freire-Gormaly, Ellen Van Wijngaarden, Melina Tahami
Publikováno v:
Progress in Canadian Mechanical Engineering. Volume 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fba661a41d61e169be61438e645b88a
https://doi.org/10.32393/csme.2021.82
https://doi.org/10.32393/csme.2021.82
Microfluidic devices have been introduced for phenotypic screening of zebrafish larvae in both fundamental and pre-clinical research. One of the remaining challenges for the broad use of microfluidic devices is their limited throughput, especially in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de91268b3b69aed72bd085b9b5cd0c8
https://doi.org/10.22541/au.161308782.23900270/v1
https://doi.org/10.22541/au.161308782.23900270/v1
Publikováno v:
Biotechnology Journal. 17:2100076
BACKGROUND Microfluidic devices are being used for phenotypic screening of zebrafish larvae in fundamental and pre-clinical research. A challenge for the broad use of these microfluidic devices is their low throughput, especially in behavioral assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef64fd8e5c07a83b9b28df0feeb41120
https://doi.org/10.1002/biot.202100076
https://doi.org/10.1002/biot.202100076