Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Ellen Wright Clayton"'
Autor:
Jia Guo, Ellen Wright Clayton, Murat Kantarcioglu, Yevgeniy Vorobeychik, Myrna Wooders, Zhiyu Wan, Zhijun Yin, Bradley A. Malin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract As recreational genomics continues to grow in its popularity, many people are afforded the opportunity to share their genomes in exchange for various services, including third-party interpretation (TPI) tools, to understand their predisposit
Externí odkaz:
https://doaj.org/article/cfce51827cb9444586314efed1e8b8d5
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e43251 (2023)
The potential of artificial intelligence (AI) to reduce health care disparities and inequities is recognized, but it can also exacerbate these issues if not implemented in an equitable manner. This perspective identifies potential biases in each stag
Externí odkaz:
https://doaj.org/article/63c506fd287447c6a09d0bd60ec7112f
Autor:
Yongtai Liu, Zhijun Yin, Zhiyu Wan, Chao Yan, Weiyi Xia, Congning Ni, Ellen Wright Clayton, Yevgeniy Vorobeychik, Murat Kantarcioglu, Bradley A Malin
Publikováno v:
JMIR Infodemiology, Vol 2, Iss 2, p e35702 (2022)
BackgroundAs direct-to-consumer genetic testing services have grown in popularity, the public has increasingly relied upon online forums to discuss and share their test results. Initially, users did so anonymously, but more recently, they have includ
Externí odkaz:
https://doaj.org/article/9a44a08945a242169c852cf46a86c434
Autor:
Congning Ni, Zhiyu Wan, Chao Yan, Yongtai Liu, Ellen Wright Clayton, Bradley Malin, Zhijun Yin
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 3, p e31687 (2022)
BackgroundIn November 2018, a Chinese researcher reported that his team had applied clustered regularly interspaced palindromic repeats or associated protein 9 to delete the gene C-C chemokine receptor type 5 from embryos and claimed that the 2 newbo
Externí odkaz:
https://doaj.org/article/245c130240724a83850906c73505f65e
Autor:
Amy A. Blumling, Cynthia A. Prows, Margaret H. Harr, Wendy K. Chung, Ellen Wright Clayton, Ingrid A. Holm, Georgia L. Wiesner, John J. Connolly, John B. Harley, Hakon Hakonarson, Michelle L. McGowan, Erin M. Miller, Melanie F. Myers
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 11, p 1910 (2022)
Purpose: The electronic Medical Records and Genomics (eMERGE) Phase III study was undertaken to assess clinical utility of returning medically actionable genomic screening results. We assessed pediatric clinical outcomes following return of pathogeni
Externí odkaz:
https://doaj.org/article/f28f510dd2c4439db07b4e0fb1f72c40
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249267 (2021)
BackgroundConflicts of interest (COI) jeopardize the validity of Clinical Practice Guidelines (CPGs). When the Institute of Medicine promulgated COI policies in 2011, few organizations met these requirements, but it is unknown if organizations have i
Externí odkaz:
https://doaj.org/article/36e63538822044efa30b04cb89478df6
Autor:
James W Hazel, Catherine Hammack-Aviran, Kathleen M Brelsford, Bradley A Malin, Laura M Beskow, Ellen Wright Clayton
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260340 (2021)
Direct-to-consumer genetic testing is marketed as a tool to uncover ancestry and kin. Recent studies of actual and potential users have demonstrated that individuals' responses to the use of these tests for these purposes are complex, with privacy, d
Externí odkaz:
https://doaj.org/article/0720c85c4a904773b6b7533fd81d27ae
Autor:
Maureen E. Smith, Saskia C. Sanderson, Kyle B. Brothers, Melanie F. Myers, Jennifer McCormick, Sharon Aufox, Martha J. Shrubsole, Nanibaá A. Garrison, Nathaniel D. Mercaldo, Jonathan S. Schildcrout, Ellen Wright Clayton, Armand H. Matheny Antommaria, Melissa Basford, Murray Brilliant, John J. Connolly, Stephanie M. Fullerton, Carol R. Horowitz, Gail P. Jarvik, Dave Kaufman, Terri Kitchner, Rongling Li, Evette J. Ludman, Catherine McCarty, Valerie McManus, Sarah Stallings, Janet L. Williams, Ingrid A. Holm
Publikováno v:
BMC Medical Research Methodology, Vol 16, Iss 1, Pp 1-11 (2016)
Abstract Background As biobanks play an increasing role in the genomic research that will lead to precision medicine, input from diverse and large populations of patients in a variety of health care settings will be important in order to successfully
Externí odkaz:
https://doaj.org/article/3256bdbf3777489491af7c85b9d804ac
Autor:
Georgia L. Wiesner, Alanna Kulchak Rahm, Paul Appelbaum, Sharon Aufox, Sarah T. Bland, Carrie L. Blout, Kurt D. Christensen, Wendy K. Chung, Ellen Wright Clayton, Robert C. Green, Margaret H. Harr, Nora Henrikson, Christin Hoell, Ingrid A. Holm, Gail P. Jarvik, Iftikhar J. Kullo, Philip E. Lammers, Eric B. Larson, Noralane M. Lindor, Maddalena Marasa, Melanie F. Myers, Josh F. Peterson, Cynthia A. Prows, James D. Ralston, Hila Milo Rasouly, Richard R. Sharp, Maureen E. Smith, Sara L. Van Driest, Janet L. Williams, Marc S. Williams, Julia Wynn, Kathleen A. Leppig
Publikováno v:
Journal of Personalized Medicine, Vol 10, Iss 2, p 30 (2020)
A goal of the 3rd phase of the Electronic Medical Records and Genomics (eMERGE3) Network was to examine the return of results (RoR) of actionable variants in more than 100 genes to consenting participants and their healthcare providers. Each of the 1
Externí odkaz:
https://doaj.org/article/9adbd2515be142cca8ebd1ce1b4cda9d
Autor:
Christine Y. Lu, Stephanie Loomer, Rachel Ceccarelli, Kathleen M. Mazor, James Sabin, Ellen Wright Clayton, Geoffrey S. Ginsburg, Ann Chen Wu
Publikováno v:
Journal of Personalized Medicine, Vol 8, Iss 2, p 19 (2018)
Insurance coverage policies are a major determinant of patient access to genomic tests. The objective of this study was to examine differences in coverage policies for guideline-recommended pharmacogenomic tests that inform cancer treatment. We analy
Externí odkaz:
https://doaj.org/article/a8fe55dff21f411c89ffd571499bee9d