Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ellen Wirawan"'
Autor:
Troy T. Rohn, Ellen Wirawan, Raquel J. Brown, Jordan R. Harris, Eliezer Masliah, Peter Vandenabeele
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 68-78 (2011)
The Beclin-1 protein is essential for the initiation of autophagy, and recent studies suggest this function may be compromised in Alzheimer's disease (AD). In addition, in vitro studies have supported a loss of function of Beclin-1 due to proteolytic
Externí odkaz:
https://doaj.org/article/508cb1990fa44e32b1bf0ecc15242c9b
Autor:
Alessandra Romagnoli, Ellen Wirawan, Saskia Lippens, Peter Vandenabeele, Gian Maria Fimia, Tom Vanden Berghe, Mauro Piacentini
Publikováno v:
Autophagy; Vol 8
Beclin1(Atg6) is a well-known key regulator of autophagy. Although Beclin1 is enzymatically inert, it governs the autophagic process by regulating PtdIns3KC3-dependent generation of phosphatidylinositol3-phosphate (PtdIns(3)P) and the subsequent recr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47246e057da086c937df1cb6cfc35043
Autor:
Riet De Rycke, Ellen Wirawan, Quinten Remijsen, Eef Parthoens, Jean Willems, Samuel Noppen, Michel Delforge, Peter Vandenabeele, Tom Vanden Berghe, Bob Asselbergh
Publikováno v:
Cell Research; Vol 21
Neutrophil extracellular traps (NETs) are extracellular chromatin structures that can trap and degrade microbes. They arise from neutrophils that have activated a cell death program called NET cell death, or NETosis. Activation of NETosis has been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c790e693866a420c8d0ca8efab49e7f
https://doi.org/10.1038/cr.2010.150
https://doi.org/10.1038/cr.2010.150
Publikováno v:
Microbes and Infection; Vol 11
Cell death is a crucial process during development, homeostasis and immune regulation of multicellular organisms, and its dysregulation is associated with numerous pathologies. Cell death is often induced upon pathogen infection as part of the defens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce5a38f59b2a4be4bad55c273352d51
Autor:
Gian Maria Fimia, Fabiola Ciccosanti, Marco Corazzari, Vittoria Pagliarini, Mauro Piacentini, Alessandra Romagnoli, Ellen Wirawan, Francesco Cecconi, Peter Vandenabeele, Saskia Lippens, G Lisi
Publikováno v:
Cell Death and Differentiation; Vol 19
Under stress conditions, pro-survival and pro-death processes are concomitantly activated and the final outcome depends on the complex crosstalk between these pathways. In most cases, autophagy functions as an early-induced cytoprotective response, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1327916e6aa81f67a66640165939eaad
https://hdl.handle.net/11587/395256
https://hdl.handle.net/11587/395256
Publikováno v:
Cell Research; Vol 22
Autophagy is a lysosomal degradation pathway that degrades damaged or superfluous cell components into basic biomolecules, which are then recycled back into the cytosol. In this respect, autophagy drives a flow of biomolecules in a continuous degrada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f594450f2c746e49245d54bc13b6f18
https://europepmc.org/articles/PMC3351915/
https://europepmc.org/articles/PMC3351915/
Autor:
Nele Festjens, Mohamed Lamkanfi, Ellen Wirawan, Jelle Verspurten, Xavier Saelens, Peter Vandenabeele, Lieselotte Vande Walle, Tom Vanden Berghe
Publikováno v:
Cell Research; Vol 20
Interleukin-3 (IL-3) deprivation of the mouse pro-B cell line Ba/F3 induces cell death that is abrogated by B-cell lymphoma 2 (Bcl-2) overexpression, but remains unaffected by the pan-caspase inhibitor carbobenzoxy-valyl-analyl-aspartyl-[O-methyl]-fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27b5c41ebb2c2b785cd32d944e5b6d0
https://pubmed.ncbi.nlm.nih.gov/20125124
https://pubmed.ncbi.nlm.nih.gov/20125124