Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ellen Townes-Anderson"'
Autor:
Ellen Townes-Anderson, Éva Halász, Ilene Sugino, Amy L. Davidow, Laura J. Frishman, Luke Fritzky, Fawad A. K. Yousufzai, Marco Zarbin
Publikováno v:
Cells, Vol 12, Iss 11, p 1485 (2023)
Attachment of a detached retina does not always restore vision to pre-injury levels, even if the attachment is anatomically successful. The problem is due in part to long-term damage to photoreceptor synapses. Previously, we reported on damage to rod
Externí odkaz:
https://doaj.org/article/6c4e8862a31f4cf1bffdab749d1363ef
Autor:
Éva Halász, Marco A. Zarbin, Amy L. Davidow, Laura J. Frishman, Peter Gombkoto, Ellen Townes-Anderson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Retinal detachment (RD) causes damage, including disjunction, of the rod photoreceptor-bipolar synapse, which disrupts vision and may contribute to the poor visual recovery observed after retinal reattachment surgery. We created a model of i
Externí odkaz:
https://doaj.org/article/121a346046be44c38febc68140c3e75e
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1471-1472 (2020)
Externí odkaz:
https://doaj.org/article/7a1f0d9e90114250a9783d7d555cada1
Autor:
Eva Halasz, Ellen Townes-Anderson
Publikováno v:
ADMET and DMPK, Vol 4, Iss 4, Pp 280-301 (2016)
Rho kinases (ROCKs) have a crucial role in actin-cytoskeletal reorganization and thus are involved in broad aspects of cell motility, from smooth muscle contraction to neurite outgrowth. The first marketed ROCK inhibitor, called fasudil, has been use
Externí odkaz:
https://doaj.org/article/32bdeb28d9f8484e99a62df958ca2c35
Autor:
Weiwei Wang, Ellen Townes-Anderson
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 7, Pp 1029-1032 (2016)
The structural plasticity of synaptic terminals contributes to normal nervous system function but also to neural degeneration, in the form of terminal retraction, and regeneration, due to process growth. Synaptic morphological change is mediated thro
Externí odkaz:
https://doaj.org/article/c811915dfa70430c903e57acbaa78902
Autor:
Frank H. Kung, Ellen Townes-Anderson
Publikováno v:
Methods and Protocols, Vol 3, Iss 2, p 44 (2020)
Precise creation, maintenance, and monitoring of neuronal circuits would facilitate the investigation of subjects such as neuronal development or synaptic plasticity, or assist in the development of neuronal prosthetics. Here we present a method to p
Externí odkaz:
https://doaj.org/article/7a28c1117cdd40fea6559eaf20e6cd5f
Autor:
Jianzhong Han, Ellen Townes-Anderson
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50552 (2012)
Pikachurin is a recently identified, highly conserved, extracellular matrix-like protein. Murine pikachurin has 1,017 amino acids (~110 kDa), can bind to α-dystroglycan, and has been found to localize mainly in the synaptic cleft of photoreceptor ri
Externí odkaz:
https://doaj.org/article/efd8e3efa4304b0195b76f6c6e70cb27
Publikováno v:
Stem Cells Translational Medicine
Retinal cell therapy can have the objectives of rescue (i.e., modulation of metabolic abnormalities primarily for sight preservation) as well as replacement (i.e., replace cells lost due to injury or disease for sight restoration as well as preservat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424daaf8a175dd348ed49dee573fa0e6
https://doi.org/10.1002/sctm.18-0282
https://doi.org/10.1002/sctm.18-0282
Autor:
Laura J. Frishman, Amy L. Davidow, Eva Halasz, Ellen Townes-Anderson, Peter Gombkoto, Marco A. Zarbin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Retinal detachment (RD) causes damage, including disjunction, of the rod photoreceptor-bipolar synapse, which disrupts vision and may contribute to the poor visual recovery observed after retinal reattachment surgery. We created a model of iatrogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467d8c78a2a9329927033a5567a09e1f
https://doi.org/10.1038/s41598-020-80267-4
https://doi.org/10.1038/s41598-020-80267-4
Publikováno v:
Current opinion in ophthalmology. 31(3)
Purpose of review Retinal detachment initiates a series of events that lead to degenerative changes in retinal synaptic architecture as well as the well-known phenomena of gliosis and photoreceptor apoptosis. Retinal reattachment does not always resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4126d2f421b30d61aaac19aafc5ec4
https://pubmed.ncbi.nlm.nih.gov/32235252
https://pubmed.ncbi.nlm.nih.gov/32235252