Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ellen S. Shang"'
Publikováno v:
Infection and Immunity. 69:4094-4102
In this study, skin histopathology from naive and infection-derived immune rabbits was compared following intradermal challenge usingBorrelia burgdorferiB31 strain. The presence or absence of spirochetes in relationship to host cellular immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8a68f17aed631f3568620f9316b345
https://doi.org/10.1128/iai.69.6.4094-4102.2001
https://doi.org/10.1128/iai.69.6.4094-4102.2001
Publikováno v:
Infection and Immunity. 69:593-598
We have recently found that strain B31 infection-immune rabbits are completely protected against homologous challenge with large numbers (>10 6 ) of host-adapted Borrelia burgdorferi (HAB) (E. S. Shang, C. I. Champion, X. Wu, J. T. Skare, D. B. Blanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9b3c389b6f9f6a1be4dcf64ab032c4
https://doi.org/10.1128/iai.69.1.593-598.2001
https://doi.org/10.1128/iai.69.1.593-598.2001
Autor:
Hongwei H. Zhang, M. M. Exner, David R. Blanco, Michael Lovett, James N. Miller, Martin L. Phillips, Cheryl I. Champion, Ellen S. Shang
Publikováno v:
Journal of Bacteriology. 181:7168-7175
We have previously observed that while native Treponema pallidum rare outer membrane protein 1 (Tromp1) is hydrophobic and has porin activity, recombinant forms of Tromp1 do not possess these properties. In this study we show that these properties ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779265f5bd85c3f5608c1aeddaf93e6c
https://doi.org/10.1128/jb.181.23.7168-7175.1999
https://doi.org/10.1128/jb.181.23.7168-7175.1999
Autor:
David R. Blanco, Cheryl I. Champion, Michael A. Lewinski, Ellen S. Shang, Stephen G. Simkins, James N. Miller, Michael A. Lovett
Publikováno v:
The Journal of Immunology. 163:2741-2746
The purpose of this study was to determine whether immunization with purified outer membrane vesicles (OMV) from Treponema pallidum (T.p.) could elicit Abs capable of killing this organism. It is well established that the immunization of rabbits or m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aeda8649477a563652ae117440e7cf1
https://doi.org/10.4049/jimmunol.163.5.2741
https://doi.org/10.4049/jimmunol.163.5.2741
Autor:
David A. Haake, Jay D. Pruetz, Ellen S. Shang, Carole A. Bolin, Mary K. Mazel, Carleen Martinich, Theresa A. Summers, Adam M. McCoy
Publikováno v:
Infection and Immunity. 66:1579-1587
We report the cloning of the gene encoding a 36-kDa leptospiral outer membrane lipoprotein, designated LipL36. We obtained the N-terminal amino acid sequence of a staphylococcal V8 proteolytic-digest fragment in order to design an oligonucleotide pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26c43e84018672304bdd34e7aa50f2b
https://doi.org/10.1128/iai.66.4.1579-1587.1998
https://doi.org/10.1128/iai.66.4.1579-1587.1998
Autor:
Ellen S. Shang, Bruce L. Kagan, M. M. Exner, Michael Lovett, James N. Miller, Jonathan T. Skare, David R. Blanco
Publikováno v:
Infection and Immunity. 66:1082-1091
The outer membrane of Borrelia hermsii has been shown by freeze-fracture analysis to contain a low density of membrane-spanning outer membrane proteins which have not yet been isolated or identified. In this study, we report the purification of outer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1008f9d8c92da633b2407f739a98c527
https://doi.org/10.1128/iai.66.3.1082-1091.1998
https://doi.org/10.1128/iai.66.3.1082-1091.1998
Autor:
Ellen S. Shang, David R. Blanco, Jonathan T. Skare, Bruce E. Kagan, M A Lovett, James N. Miller, Sven Bergström, Paul Tempst, Tajib Mirzabekov, Hediye Erdjument-Bromage, Jonas Bunikis
Publikováno v:
Infection and Immunity. 65:3654-3661
In this study we report the purification and characterization of a 66-kDa protein, designated Oms66, for outer membrane-spanning 66-kDa protein, that functions as a porin in the outer membrane (OM) of Borrelia burgdorferi. Oms66 was purified by fast-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6534451bc699dc2c0e1bfea707ffa9bd
https://doi.org/10.1128/iai.65.9.3654-3661.1997
https://doi.org/10.1128/iai.65.9.3654-3661.1997
Autor:
Ellen S. Shang, Jon T. Skare, H Erdjument-Bromage, P Tempst, James N. Miller, David R. Blanco, Michael A. Lovett
Publikováno v:
Journal of Bacteriology. 179:2238-2246
We report the purification, molecular cloning, and characterization of a 40-kDa glycerophosphodiester phosphodiesterase homolog from Borrelia hermsii. The 40-kDa protein was solubilized from whole organisms with 0.1% Triton X-100, phase partitioned i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ce50f00a0251e9ab598ba1e44b0402
https://doi.org/10.1128/jb.179.7.2238-2246.1997
https://doi.org/10.1128/jb.179.7.2238-2246.1997
Autor:
Michael Lovett, David R. Blanco, Tajib Mirzabekov, Yuri Sokolov, Cheryl I. Champion, Denise M. Foley, Jonathan T. Skare, Bruce L. Kagan, James N. Miller, Ellen S. Shang
Publikováno v:
Journal of Clinical Investigation. 96:2380-2392
We have isolated and purified outer membrane vesicles (OMV) from Borrelia burgdorferi strain B31 based on methods developed for isolation of Treponema pallidum OMV. Purified OMV exhibited distinct porin activities with conductances of 0.6 and 12.6 na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcecd88b60f04c9e779d8b011b4efa1b
https://doi.org/10.1172/jci118295
https://doi.org/10.1172/jci118295
Autor:
Xiao-Yang Wu, Michael A. Lovett, James N. Miller, Jonathan T. Skare, David R. Blanco, Ellen S. Shang, Cheryl I. Champion
In this study, infection-derived immunity in the rabbit model of Lyme disease was compared to immunity following immunization with purified outer membrane vesicles (OMV) isolated fromBorrelia burgdorferiand recombinant outer surface protein A (OspA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e68fdb4c0055d71900939a95d27a7a1
https://europepmc.org/articles/PMC101723/
https://europepmc.org/articles/PMC101723/
