Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ellen S. Morgan"'
Publikováno v:
Nature Protocols. 9:2382-2394
Precise immunolocalization of proteins within a cell is central to understanding cell processes and functions such as intracellular trafficking and secretion of molecules during immune responses. Here we describe a protocol for ultrastructural detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ea63ac3f72d2f962df08add7975c79
https://doi.org/10.1038/nprot.2014.163
https://doi.org/10.1038/nprot.2014.163
Autor:
Sandra Kissing, Nitin Kulkarni, Stefan Kraft, Jean-Pierre Kinet, Paul Saftig, Bernd Schröder, Marie-Hélène Jouvin, Ann M. Dvorak, Ellen S. Morgan
Publikováno v:
The Journal of Immunology. 191:2871-2878
Mast cell (MC) activation through the high-affinity IgE receptor FcεRI leads to the release of mediators involved in immediate-type allergic reactions. Although Abs against the tetraspanins CD63 and CD81 inhibit FcεRI-induced MC degranulation, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373944170bc206c3e06e5f2512ae7408
https://doi.org/10.4049/jimmunol.1202323
https://doi.org/10.4049/jimmunol.1202323
Autor:
Lisa A. Spencer, Rossana C. N. Melo, Staci P. Bafford, Peter F. Weller, Ann M. Dvorak, Sandra A.C. Perez, Josiane S. Neves, Ellen S. Morgan
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Major basic protein (MBP), the predominant cationic protein of human eosinophil specific granules, is stored within crystalloid cores of these granules. Secretion of MBP contributes to the immunopathogenesis of varied diseases. Prior electron microsc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0709054113c7c6ed8e850ec91efd7d82
https://doi.org/10.1038/labinvest.2009.40
https://doi.org/10.1038/labinvest.2009.40
Autor:
Lars Hellman, Ellen S. Morgan, Ann M. Dvorak, Hans Reimer Rodewald, Annette Tietz, Carmen Blum, Hans Jörg Fehling, Anita H. Straus, Thorsten B. Feyerabend, Helio K. Takahashi, Heinz Hausser
Publikováno v:
Molecular and Cellular Biology. 25:6199-6210
Mast cell carboxypeptidase A (Mc-cpa) is a highly conserved secretory granule protease. The onset of expression in mast cell progenitors and lineage specificity suggest an important role for Mc-cpa in mast cells. To address the function of Mc-cpa, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e36594c4891f39b19b90edadcca2b95
https://doi.org/10.1128/mcb.25.14.6199-6210.2005
https://doi.org/10.1128/mcb.25.14.6199-6210.2005
Autor:
Fred D. Finkelman, Ann M. Dvorak, William E. Paul, Jinfang Zhu, Melanie Prout, Joseph F. Urban, Dragana Jankovic, Booki Min, Ellen S. Morgan, Graham LeGros, Jane Hu-Li
Publikováno v:
The Journal of Experimental Medicine
Using mice in which the eGfp gene replaced the first exon of the Il4 gene (G4 mice), we examined production of interleukin (IL)-4 during infection by the intestinal nematode Nippostrongylus brasiliensis (Nb). Nb infection induced green fluorescent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af39af06d67762664ed9c9a399b4969a
http://europepmc.org/articles/PMC2211939
http://europepmc.org/articles/PMC2211939
Autor:
Ellen S. Morgan, Ann M. Dvorak
Publikováno v:
Immunological Reviews. 179:94-101
The distribution of ribosomes was investigated in mature human mast cells with a chelation-based staining protocol known to bleach DNA-rich structures, leaving RNA-rich structures unbleached. With this method, electron-dense ribosomes were adjacent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645e1657fa1fcb5815fe71aa5012fd94
https://doi.org/10.1034/j.1600-065x.2001.790110.x
https://doi.org/10.1034/j.1600-065x.2001.790110.x
Publikováno v:
The Histochemical Journal. 33:397-402
Isolated human lung mast cells were used to identify subcellular sites of basic fibroblast growth factor using a postembedding immunogold method. The factor was present in quantity in secretory granules and cytoplasmic lipid bodies. Cisterns of smoot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::134b56f61dba46803fa7b17c2d5a1442
https://doi.org/10.1023/a:1013771827069
https://doi.org/10.1023/a:1013771827069
Autor:
Ann M. Dvorak, Ellen S. Morgan
Publikováno v:
The Histochemical Journal. 32:423-438
Mature human mast cells are classical secretory cells that are filled with secretory-storage granules but are poorly endowed with visible free or membrane-bound cytoplasmic ribosomes. We recently reported close associations of ribosomes and various c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cba0fa27255217c25a9933e11c3dfcc
https://doi.org/10.1023/a:1004043305714
https://doi.org/10.1023/a:1004043305714
Autor:
Ann M. Dvorak, Ellen S. Morgan
Publikováno v:
The Histochemical Journal. 32:685-696
Human mast cells are professional secretory cells that store synthetic products in large granules filling their cytoplasm. Unlike many secretory cells, the principal synthetic organelle, ribosome-rich endoplasmic reticulum, is a minor component of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf278bdbf83f80318bd90c8e70a270c2
https://doi.org/10.1023/a:1004119500801
https://doi.org/10.1023/a:1004119500801
Autor:
Robert P. Schleimer, Ann M. Dvorak, Ellen S. Morgan, Lawrence M. Lichtenstein, Peter F. Weller
Publikováno v:
Journal of Histochemistry & Cytochemistry. 48:1-12
The distribution of ribosomes in mature human mast cells, a major granulated secretory cell, does not resemble that in other secretory cells, such as pancreatic acinar cells and plasma cells. By routine ultrastructural analysis, ribosomes in human ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac20a01f3c4cabf4cf2e106f5377c127
https://doi.org/10.1177/002215540004800101
https://doi.org/10.1177/002215540004800101