Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ellen R. Gillespie"'
Autor:
Ellen R. Gillespie, Laura F. Grice, Isabel G. Courtney, Hong Wa Lao, Woncheol Jung, Sonny Ramkomuth, Jacky Xie, David A. Brown, James Walsham, Kristen J. Radford, Quan H. Nguyen, Marc J. Ruitenberg
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Next-generation humanised mouse models and single-cell RNA sequencing (scRNAseq) approaches enable in-depth studies into human immune cell biology. Here we used NSG-SGM3 mice engrafted with human umbilical cord haematopoietic stem cells to i
Externí odkaz:
https://doaj.org/article/40a7cde76523424a9dc3bc7e32ce0e7a
Autor:
Abi G. Yates, Trisha Jogia, Ellen R. Gillespie, Yvonne Couch, Marc J. Ruitenberg, Daniel C. Anthony
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response are thought to drive secondary inflammatory pathology at the lesion site
Externí odkaz:
https://doaj.org/article/9b745970b3bd4226916948af6c72f887
Autor:
Emily F. Willis, Ellen R. Gillespie, Kirsten Guse, Adrian W. Zuercher, Fabian Käsermann, Marc J. Ruitenberg, Jana Vukovic
Publikováno v:
Brain, Behavior, and Immunity. 109:37-50
Intravenous immunoglobulin (IVIG) is a promising immune-modulatory therapy for limiting harmful inflammation and associated secondary tissue loss in neurotrauma. Here, we show that IVIG therapy attenuates spatial learning and memory deficits followin
Autor:
Victoria S. Foster, Natalie J. Saez, Ellen R. Gillespie, Trisha Jogia, Chantelle Reid, Snezana Maljevic, Woncheol Jung, Hong W. Lao, Marc J. Ruitenberg, Glenn F. King
Publikováno v:
Journal of Neurotrauma.
Autor:
Daniel C. Anthony, Abi G. Yates, Marc J. Ruitenberg, Ellen R. Gillespie, Yvonne Couch, Trisha Jogia
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-12 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response are thought to drive secondary inflammatory pathology at the lesion site, and sup
Autor:
Marc J. Ruitenberg, Ellen R. Gillespie
Publikováno v:
Journal of neurotrauma. 39(3-4)
Traumatic spinal cord injury (SCI) elicits a complex cascade of cellular and molecular inflammatory events. Although certain aspects of the inflammatory response are essential to wound healing and repair, post-SCI inflammation is, on balance, thought
Autor:
Stefan Rose-John, Jana Vukovic, Adahir Labrador Garrido, Marc J. Ruitenberg, Wayne A. Schroder, Ellen R. Gillespie, Kelli P. A. MacDonald, Emily F. Willis, Daniel C. Anthony, Quan Nguyen, Perry F. Bartlett, Abi G. Yates, Samuel B. R. Harley
Publikováno v:
Cell. 180(5)
Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and secondary inflammatory pathology remains poorly understood. Here, we show that removal of microgl
Autor:
Gail M. Williams, Frederic A. Meunier, Trisha Jogia, Jean-Pierre Levesque, Linda V. Blomster, Bianca Nowlan, Ellen R. Gillespie, Kate E. Campbell, Marc J. Ruitenberg, Xaria X. Li, Trent M. Woodruff, Esther Jacobson, Geoff W. Osborne, Faith H. Brennan, Kelli P. A. MacDonald, Stephen M. Taylor
Publikováno v:
JCI Insight. 4
Traumatic spinal cord injury (SCI) triggers an acute-phase response that leads to systemic inflammation and rapid mobilization of bone marrow (BM) neutrophils into the blood. These mobilized neutrophils then accumulate in visceral organs and the inju