Gonadotropin-releasing hormone receptor (Gnrhr) gene knock out: Normal growth and development of sensory, motor and spatial orientation behavior but altered metabolism in neonatal and prepubertal mice.

Autor: Ellen R Busby, Nancy M Sherwood

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174452 (2017)

Gonadotropin-releasing hormone (GnRH) is important in the control of reproduction, but its actions in non-reproductive processes are less well known. In this study we examined the effect of disrupting the GnRH receptor in mice to determine if growth,

Externí odkaz: https://doaj.org/article/157c2012927e4111abde406db7c9f17f

Sexual Differentiation of the Brain Requires Perinatal Kisspeptin-GnRH Neuron Signaling

Autor: Jenny Clarkson, Günther Schütz, Nancy M. Sherwood, Ellen R. Busby, Allan E. Herbison, Milen Kirilov

Publikováno v: The Journal of Neuroscience. 34:15297-15305

Sex differences in brain function underlie robust differences between males and females in both normal and disease states. Although alternative mechanisms exist, sexual differentiation of the male mammalian brain is initiated predominantly by testost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72cea6f41544289d64ba14f5854c549
https://doi.org/10.1523/jneurosci.3061-14.2014

GnRH receptors and peptides: skating backward

Autor: Nancy M. Sherwood, Graeme J. Roch, Ellen R. Busby

Publikováno v: General and comparative endocrinology. 209

Gonadotropin-releasing hormone (GnRH) and its receptor are essential for reproduction in vertebrates. Although there are three major types of GnRH peptides and two major types of receptors in vertebrates, the pattern of distribution is unusual. Evide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d335ff25dd84a3b6cd38886276903da
https://pubmed.ncbi.nlm.nih.gov/25107740

List of Contributors

Autor: Greti Aguilera, Deanna M. Arble, Iñigo Azcoitia, Sarah L. Berga, Wah Chin Boon, Pierre M.G. Bouloux, Cyril Y. Bowers, Ellen R. Busby, Rebecca Campbell, Frances A. Champagne, Evangelia Charmandari, Alon Chen, George P. Chrousos, Iain J. Clarke, Georges Copinschi, Virginia L. Crowder, James P. Curley, Wouter W. de Herder, E. Ronald de Kloet, Ines Donangelo, Alison J. Douglas, Dana Erickson, Richard A. Feelders, George Fink, Luis M. Garcia-Segura, Thang S. Han, Leo J. Hofland, Ali Iranmanesh, Marian Joëls, Ilia N. Karatsoreos, Henk Karst, Tomoshige Kino, Joseph R. Kurian, Dik J. Kwekkeboom, Steven W. Lamberts, Lawrence C. Layman, Gareth Leng, Jon E. Levine, Malcolm J. Low, Mike Ludwig, Margaret M. McCarthy, Bruce S. McEwen, Marilyn Y. McGinnis, Shlomo Melmed, Robert P. Millar, Ali Mohamadi, Randy J. Nelson, Claire L. Newton, Donald W. Pfaff, Vincent Prevot, Graeme J. Roch, Ferdinand Roelfsema, Antonia K. Roseweir, David R. Rubinow, Katya B. Rubinow, Randall R. Sakai, Roberto Salvatori, Willis K. Samson, Peter J. Schmidt, Karen A. Scott, Barbara B. Sherwin, Nancy M. Sherwood, Aniket R. Sidhaye, Evan R. Simpson, Jeremy T. Smith, Yolanda R. Smith, Edward M. Stricker, Yehezkel Sztainberg, Kellie L.K. Tamashiro, Ei Terasawa, Brian C. Trainor, Fred W. Turek, Eve Van Cauter, Johannes D. Veldhuis, Joseph G. Verbalis, Martha H. Vitaterna, Alan G. Watts, Fredric E. Wondisford, Susan Wray, Gina L.C. Yosten, R. Thomas Zoeller

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54998a377e9e64572852b1c619b36ec3
https://doi.org/10.1016/b978-0-12-375097-6.10042-3

The deep evolutionary origins of GnRH and its receptor

Autor: Ellen R. Busby, Graeme J. Roch, Nancy M. Sherwood

Publikováno v: Regulatory Peptides. 177:S12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b576ffb52299ec9efed8327991c3d6cb
https://doi.org/10.1016/j.regpep.2012.05.012