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Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis
Autor:
Jeremy L. Barth, Benjamin Lee, Kyu-Ho Lee, Ellen P. Knoll, Victor M. Fresco, W. Scott Argraves, Christopher D. Clark
Publikováno v:
Developmental Dynamics. 239:2024-2033
Nkx2.5, a transcription factor implicated in human congenital heart disease, is required for regulation of second heart field (SHF) progenitors contributing to outflow tract (OFT). Here, we define a set of genes (Lrrn1, Elovl2, Safb, Slc39a6, Khdrbs1
Autor:
Tapan K Chatterjee, Ellen P Knoll, Wilson Tong, Andra L Blomkalns, Joshua E Basford, David Y Hui, Neal L Weintraub
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
During chronic overfeeding, adipose tissue expansion contributes to adipose inflammation, insulin resistance and obesity-related diabetes. Consequently, identifying mechanisms that promote “healthy” growth of adipose tissues could potentially imp