Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ellen Ngar-Yun Poon"'
Autor:
Bobo Wing-Yee Mok, Maxwell Kwok, Hung Sing Li, Lowell Ling, Angel Lai, Bin Yan, Cherie Tsz-Yiu Law, Chui Him Yeung, Anna Jinxia Zhang, Rachel Chun-Yee Tam, Anja Kukic, Conor J. Cremin, Yajie Zhang, Teng Long, Zhisen Kang, Ruibang Luo, Kam Tong Leung, Albert M. Li, Grace Lui, Stephen Kwok-Wing Tsui, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Paul K. S. Chan, Bryan P. Yan, Honglin Chen, Ellen Ngar-Yun Poon
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background COVID-19 can cause cardiac complications and the latter are associated with poor prognosis and increased mortality. SARS-CoV-2 variants differ in their infectivity and pathogenicity, but how they affect cardiomyocytes (CMs) is unc
Externí odkaz:
https://doaj.org/article/faf07cfdf22342eeb1c12ec8380cea15
Autor:
Shumin Li, Bin Yan, Binbin Wu, Junhao Su, Jianliang Lu, Tak-Wah Lam, Kenneth R. Boheler, Ellen Ngar-Yun Poon, Ruibang Luo
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Aims Dissecting complex interactions among transcription factors (TFs), microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are central for understanding heart development and function. Although computational approaches and platforms have b
Externí odkaz:
https://doaj.org/article/f35ef0b0b8ec436d818aa868c2625cf0
Autor:
Stanley Chun Ming Wu, Manyu Zhu, Stanley C. C. Chik, Maxwell Kwok, Asif Javed, Laalaa Law, Shing Chan, Kenneth R. Boheler, Yin Ping Liu, Godfrey Chi Fung Chan, Ellen Ngar-Yun Poon
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Acute graft-versus-host disease (aGvHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). Transplantation of immunosuppressive human mesenchymal stromal cells (hMSCs) can protect agai
Externí odkaz:
https://doaj.org/article/af6eaade0f0e4bf4ab3f76f787552470
Autor:
Sheng Zhu, Anna Hing Yee Law, Ruixia Deng, Ellen Ngar Yun Poon, Chun Wai Lo, Anna Ka Yee Kwong, Rui Liang, Kelvin Yuen Kwong Chan, Wai Lap Wong, Kian Cheng Tan-Un, W.W.M. Pim Pijnappel, Godfrey Chi Fung Chan, Sophelia Hoi Shan Chan
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102040- (2020)
We derived an integration-free induced pluripotent stem cell (iPSC) line from the peripheral blood mononuclear cells (PBMCs) of a 23-year-old male patient. This patient carries a 5′ splice site point mutation in intron 1 (c.31+1G>A) of the dystroph
Externí odkaz:
https://doaj.org/article/3ee2da2e3be0433e8b7b3b7d3239f0dd
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Supplementary Data from Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340814653f430c54d027ddfe44a87c37
https://doi.org/10.1158/2643-3230.22545317.v1
https://doi.org/10.1158/2643-3230.22545317.v1
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41072df45b1d12a7e0dd4c70d3befc4e
https://doi.org/10.1158/2643-3230.c.6550904
https://doi.org/10.1158/2643-3230.c.6550904
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Supplementary Figure from Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d586dd08c36ec116ff3489f689f1d
https://doi.org/10.1158/2643-3230.22545314
https://doi.org/10.1158/2643-3230.22545314
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:1023-1039
Human pluripotent stem cells (hPSC) self-renew and represent a potentially unlimited source for the production of cardiomyocytes (CMs) suitable for studies of human cardiac development, drug discovery, cardiotoxicity testing, and disease modelling an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::addf539f49dc5a0f04afbbf10918a9df
https://doi.org/10.1007/s00424-021-02549-8
https://doi.org/10.1007/s00424-021-02549-8
Autor:
Kathy Yuen Yee Chan, Po Yee Chung, Chi Zhang, Ellen Ngar Yun Poon, Alex Wing Kwan Leung, Kam Tong Leung
Publikováno v:
Journal of leukocyte biologyREFERENCES. 112(4)
G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors. They are involved in almost every physiologic process and consequently have a pivotal role in an extensive number of pathologies, including genetic, neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7868ef468cc2f793f7feac32121b63cf
https://pubmed.ncbi.nlm.nih.gov/35694792
https://pubmed.ncbi.nlm.nih.gov/35694792
Autor:
Han Wang, Kathy Yuen Yee Chan, Chi Keung Cheng, Margaret H.L. Ng, Po Yi Lee, Frankie Wai Tsoi Cheng, Grace Kee See Lam, Tin Wai Chow, Shau Yin Ha, Alan K.S. Chiang, Wing Hang Leung, Anskar Y.H. Leung, Chi Chiu Wang, Tao Zhang, Xiao-Bing Zhang, Chi Chiu So, Yuet Ping Yuen, Qiwei Sun, Chi Zhang, Yaqun Xu, John Tak Kit Cheung, Wing Hei Ng, Patrick Ming-Kuen Tang, Wei Kang, Ka-Fai To, Wayne Yuk Wai Lee, Raymond S.M. Wong, Ellen Ngar Yun Poon, Qi Zhao, Junbin Huang, Chun Chen, Patrick Man Pan Yuen, Chi-kong Li, Alex Wing Kwan Leung, Kam Tong Leung
Publikováno v:
Blood cancer discovery. 3(6)
Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca555489fe5f18c2d08b830dac9f9f2
https://pubmed.ncbi.nlm.nih.gov/35960210
https://pubmed.ncbi.nlm.nih.gov/35960210