Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ellen Mihaich"'
Publikováno v:
Environmental Toxicology and Chemistry. 38:1770-1783
The medaka extended one-generation reproduction test (MEOGRT) is a tier-2 study in the US Environmental Protection Agency's Endocrine Disruptor Screening Program and a level-5 study in the Organisation for Economic Co-operation and Development's conc
Autor:
Daniel L. Villeneuve, Katie Coady, Tamar Schlekat, Ellen Mihaich, Natàlia Garcia-Reyero, Beate I. Escher, Cheryl A. Murphy
Publikováno v:
Environmental Toxicology and Chemistry. 38:12-26
In 2007 the United States National Research Council (NRC) published a vision for toxicity testing in the 21st century that emphasized the use of in vitro high-throughput screening (HTS) methods and predictive models as an alternative to in vivo anima
Autor:
Ellen Mihaich, Christopher J. Borgert
Publikováno v:
Regulatory Toxicology and Pharmacology. 100:7-15
Exposure to benzene has many sources, from gasoline refueling to tobacco combustion. Although the toxicology of benzene is well studied, the potential for environmental exposure and a heightened interest in identifying substances that may cause toxic
Autor:
Steven Hentges, Jan Woelz, Charles A. Staples, Nelly van der Hoeven, Kathryn E. Clark, Ellen Mihaich
Publikováno v:
Chemosphere. 201:448-458
Concentrations of bisphenol A (BPA) in North American and European fresh and marine surface waters and sediments were analyzed to quantify environmental levels and evaluate trends over the years 1996-2014. In North American surface water and sediment
Autor:
Ellen Mihaich, Steven G. Hentges, Lisa S. Ortego, Jan Woelz, Gary M. Klecka, Steve Dimond, Charles A. Staples
Publikováno v:
Environmental Toxicology and Chemistry. 37:398-410
Bisphenol A (BPA) is a high production volume compound primarily used to produce epoxy resins and polycarbonate plastic. Exposure to low concentrations of BPA occurs in freshwater and marine systems, primarily from wastewater treatment plant discharg
Autor:
David A. Dreier, Markus Hecker, Yukio Kawashima, Ellen Mihaich, Christoph Schäfers, Lisa S. Ortego, Zhi-Chao Dang, Keith R. Solomon
Publikováno v:
Integrated Environmental Assessment and Management. 13:280-292
As regulatory programs evaluate substances for their endocrine-disrupting properties, careful study design and data interpretation are needed to distinguish between responses that are truly endocrine specific and those that are not. This is particula
Autor:
L. Earl Gray, James P. Meador, Gerd Maack, Lennart Weltje, James R. Wheeler, Gerald T. Ankley, Melanie Gross, Peter Matthiessen, Yukio Kawashima, Laurent Lagadic, Mike Williams, Poul Bjerregaard, Patrick D. Guiney, David A. Dreier, Jeffery C. Wolf, Joanne L. Parrott, Lisa A. Constantine, Anu Kumar, Sue Marty, Ioanna Katsiadaki, Tamar I. Schwarz, Janice E. Chambers, Markus Hecker, Zhi-Chao Dang, Nancy D. Denslow, Kristin E. Brugger, Daniel B. Pickford, Henry O. Krueger, Steve Dungey, Annegaaike Leopold, Sarah M. Kadlec, Tim Verslycke, Lisa S. Ortego, Henrik Holbech, Christoph Schaefers, Michael S. Roberts, Steven L. Levine, Taisen Iguchi, Jenny Odum, Katherine K. Coady, Keith R. Solomon, Werner Kloas, Ronald C. Biever, Christopher J. Borgert, Amy Blankinship, Ellen Mihaich, Natalie K. Karouna-Renier, Kunihiko Yamazaki
Publikováno v:
Integrated Environmental Assessment and Management. 13:267-279
A SETAC Pellston Workshop® “Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)” was held in February 2016 in Pensacola, Florida, USA. The primary objective of the workshop was to provide advice, based on c
Autor:
Charles A. Staples, Steven G. Hentges, Jan Woelz, Gary M. Klecka, Norbert Caspers, Lisa S. Ortego, Ellen Mihaich
Publikováno v:
Environmental Toxicology and Chemistry. 35:652-659
Bisphenol A (BPA) is a high production volume chemical intermediate used primarily in the production of polycarbonate plastics and epoxy resins. It primarily enters surface water and sediment via effluent discharges during its manufacture and use. Th
Autor:
Leah M. Zorrilla, Lisa S. Ortego, Ellen Mihaich, M. Sue Marty, Katie Coady, Steven L. Levine, Richard M. Green, Kun Don Yi, James R. Wheeler, Chris Borgert
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 99
The endocrine system is responsible for growth, development, maintaining homeostasis and for the control of many physiological processes. Due to the integral nature of its signaling pathways, it can be difficult to distinguish endocrine-mediated adve
Autor:
Anne Fairbrother, Ellen Mihaich, Frank A. P. C. Gobas, Kent B. Woodburn, David E. Powell, G. Allen Burton, Charles A. Staples, Stephen J. Klaine
Publikováno v:
Environmental Toxicology and Chemistry. 34:2715-2722
Decamethylcyclopentasiloxane (D5) is used in personal care products and industrial applications. The authors summarize the risks to the environment from D5 based on multiple lines of evidence and conclude that it presents negligible risk. Laboratory