Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ellen McMullen"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The metabolically demanding nature of immune response requires nutrients to be preferentially directed towards the immune system at the expense of peripheral tissues. We study the mechanisms by which this metabolic reprograming oc
Externí odkaz:
https://doaj.org/article/60a7247936f24916bf764005e37699d0
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/d1e5488ed2f74d708d0c17a8053141d5
Autor:
Michalina Kazek, Lenka Chodáková, Katharina Lehr, Lukáš Strych, Pavla Nedbalová, Ellen McMullen, Adam Bajgar, Stanislav Opekar, Petr Šimek, Martin Moos, Tomáš Doležal
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002299 (2024)
Activation of immune cells requires the remodeling of cell metabolism in order to support immune function. We study these metabolic changes through the infection of Drosophila larvae by parasitoid wasp. The parasitoid egg is neutralized by differenti
Externí odkaz:
https://doaj.org/article/6ea8d92953f143c794e2c9f4f1eac24f
Autor:
Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Neuronal function is highly energy demanding and thus requires efficient and constant metabolite delivery by glia. Drosophila glia are highly glycolytic and provide lactate to fuel neuronal metabolism. Flies are able to survive for several w
Externí odkaz:
https://doaj.org/article/b8c2899245ec42aba440cd70887a0d0f
Autor:
Helen Hertenstein, Ellen McMullen, Astrid Weiler, Anne Volkenhoff, Holger M Becker, Stefanie Schirmeier
Publikováno v:
eLife, Vol 10 (2021)
During hunger or malnutrition, animals prioritize alimentation of the brain over other organs to ensure its function and, thus, their survival. This protection, also-called brain sparing, is described from Drosophila to humans. However, little is kno
Externí odkaz:
https://doaj.org/article/f066d2db6e054b818ca5d367bacc8452
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2021)
Neuronal function is highly energy demanding, requiring efficient transport of nutrients into the central nervous system (CNS). Simultaneously the brain must be protected from the influx of unwanted solutes. Most of the energy is supplied from dietar
Externí odkaz:
https://doaj.org/article/0c0fcaaf97674fa1b0e096f374f725bf
Autor:
Sebastian Sorge, Jonas Theelke, Kerem Yildirim, Helen Hertenstein, Ellen McMullen, Stephan Müller, Christian Altbürger, Stefanie Schirmeier, Ingrid Lohmann
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: The mitochondrial electron transport chain (ETC) enables essential metabolic reactions; nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling pathway outputs are not understood. We show that Notch sig
Externí odkaz:
https://doaj.org/article/1441f278caa34f1eb6911a53bb7a25a4
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2540
The rather recent development of genetically encoded metabolite sensors has changed the way we can study metabolism in living cells, ex vivo tissues, and in vivo immensely. In recent years, these sensors have also been adapted for use in Drosophila t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::072af595326cdd84795fbba458c315ee
https://pubmed.ncbi.nlm.nih.gov/35980591
https://pubmed.ncbi.nlm.nih.gov/35980591
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a6b707feb0d3ca242c4e1cff31eb02
https://doi.org/10.1007/978-1-0716-2541-5_21
https://doi.org/10.1007/978-1-0716-2541-5_21
Neuronal function is highly energy demanding and thus requires efficient and constant metabolite delivery. Like their mammalian counterparts Drosophila glia are highly glycolytic and provide lactate to fuel neuronal metabolism. However, flies are abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbed5b29078a4449d5968c2f4d884c47
https://doi.org/10.21203/rs.3.rs-251408/v1
https://doi.org/10.21203/rs.3.rs-251408/v1