Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Ellen M. Mowry"'
Autor:
Elias S. Sotirchos, Kathryn C. Fitzgerald, Carol M. Singh, Matthew D. Smith, Maria Reyes‐Mantilla, Carrie M. Hersh, Megan H. Hyland, Ryan Canissario, Sarah B. Simmons, Georgina Arrambide, Xavier Montalban, Manuel Comabella, Robert T. Naismith, Min Qiao, Lauren B. Krupp, Jacqueline A. Nicholas, Katja Akgün, Tjalf Ziemssen, Richard Rudick, Elizabeth Fisher, Robert A. Bermel, Ellen M. Mowry, Peter A. Calabresi
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 1, Pp 84-97 (2023)
Abstract Objective Evaluation of serum neurofilament light chain (sNfL), measured using high‐throughput assays on widely accessible platforms in large, real‐world MS populations, is a critical step for sNfL to be utilized in clinical practice. Me
Externí odkaz:
https://doaj.org/article/af7dafcddd2344fa8cf6fe2ae367d591
Autor:
Sandra D. Cassard, Kathryn C. Fitzgerald, Peiqing Qian, Susan A. Emrich, Christina J. Azevedo, Andrew D. Goodman, Elizabeth A. Sugar, Daniel Pelletier, Emmanuelle Waubant, Ellen M. Mowry
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101957- (2023)
Summary: Background: Vitamin D insufficiency is associated with risk of multiple sclerosis (MS) relapse; whether supplementation influences prognosis is unknown. The Vitamin D to Ameliorate MS (VIDAMS) trial aimed to determine if high dose (5000 Inte
Externí odkaz:
https://doaj.org/article/69c9ea3f31e64e10b6bb133f8bf54f0a
Autor:
Kathryn C. Fitzgerald, Pavan Bhargava, Matthew D. Smith, Diane Vizthum, Bobbie Henry-Barron, Michael D. Kornberg, Sandra D. Cassard, Dimitrios Kapogiannis, Patrick Sullivan, David J. Baer, Peter A. Calabresi, Ellen M. Mowry
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104124- (2022)
Summary: Background: Intermittent fasting or calorie restriction (CR) diets provide anti-inflammatory and neuroprotective advantages in models of multiple sclerosis (MS); data in humans are sparse. Methods: We conducted a randomised-controlled feedin
Externí odkaz:
https://doaj.org/article/5441a626d0a8432ebb2267ef4458b889
Autor:
Lianrui Zuo, Blake E. Dewey, Yihao Liu, Yufan He, Scott D. Newsome, Ellen M. Mowry, Susan M. Resnick, Jerry L. Prince, Aaron Carass
Publikováno v:
NeuroImage, Vol 243, Iss , Pp 118569- (2021)
In magnetic resonance (MR) imaging, a lack of standardization in acquisition often causes pulse sequence-based contrast variations in MR images from site to site, which impedes consistent measurements in automatic analyses. In this paper, we propose
Externí odkaz:
https://doaj.org/article/c7f72d8dec0146e8ad69609eb4990e55
Autor:
Sachin P. Gadani, Maria Reyes-Mantilla, Larissa Jank, Samantha Harris, Morgan Douglas, Matthew D. Smith, Peter A. Calabresi, Ellen M. Mowry, Kathryn C. Fitzgerald, Pavan Bhargava
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103636- (2021)
Background: Sphingosine-1-phosphate receptor (S1P) modulators and anti-CD20 therapies impair humoral responses to SARS-CoV-2 mRNA vaccines. Relatively few studies have assessed the impact of an array of disease modifying therapies (DMTs) for multiple
Externí odkaz:
https://doaj.org/article/c9007f0f052b4829be8d1ab5a3eb2a56
Autor:
Kathryn C. Fitzgerald, Matthew D. Smith, Sol Kim, Elias S. Sotirchos, Michael D. Kornberg, Morgan Douglas, Bardia Nourbakhsh, Jennifer Graves, Ramandeep Rattan, Laila Poisson, Mirela Cerghet, Ellen M. Mowry, Emmanuelle Waubant, Shailendra Giri, Peter A. Calabresi, Pavan Bhargava
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100424- (2021)
Summary: The circulating metabolome provides unique insights into multiple sclerosis (MS) pathophysiology, but existing studies are relatively small or characterized limited metabolites. We test for differences in the metabolome between people with M
Externí odkaz:
https://doaj.org/article/4da3377c4e224d5891597f599d4b2ff6
Autor:
Dohyup Kim, Emily E. Witt, Simone Schubert, Elias Sotirchos, Pavan Bhargava, Ellen M. Mowry, Karen Sachs, Biter Bilen, Lawrence Steinman, Avni Awani, Zihuai He, Peter A. Calabresi, Keith Van Haren
Publikováno v:
Nutrients, Vol 14, Iss 22, p 4737 (2022)
Vitamin D is a steroid hormone that has been widely studied as a potential therapy for multiple sclerosis and other inflammatory disorders. Pre-clinical studies have implicated vitamin D in the transcription of thousands of genes, but its influence m
Externí odkaz:
https://doaj.org/article/40453e4327184fe290cc851006086ac1
Autor:
Ellen M. Mowry, Robert A. Bermel, James R. Williams, Tammie L. S. Benzinger, Carl de Moor, Elizabeth Fisher, Carrie M. Hersh, Megan H. Hyland, Izlem Izbudak, Stephen E. Jones, Bernd C. Kieseier, Hagen H. Kitzler, Lauren Krupp, Yvonne W. Lui, Xavier Montalban, Robert T. Naismith, Jacqueline A. Nicholas, Fabio Pellegrini, Alex Rovira, Maximilian Schulze, Björn Tackenberg, Mar Tintore, Madalina E. Tivarus, Tjalf Ziemssen, Richard A. Rudick
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is the first example of a learning health system in multiple sclerosis (MS). This paper describes the initial implementation of MS PATHS and initial patient
Externí odkaz:
https://doaj.org/article/6b4c3e31f7a34f3896819caba214808c
Publikováno v:
Multiple Sclerosis International, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/9797a174c2414f44b089dc72780a940e
Autor:
Darin T. Okuda, Orhun Kantarci, Christine Lebrun‐Frénay, Maria Pia Sormani, Christina J. Azevedo, Francesca Bovis, Le H. Hua, Lilyana Amezcua, Ellen M. Mowry, Christophe Hotermans, Jason Mendoza, John S. Walsh, Christian von Hehn, Wendy S. Vargas, Stacy Donlon, Robert T. Naismith, Annette Okai, Gabriel Pardo, Pavle Repovic, Olaf Stüve, Aksel Siva, Daniel Pelletier
Publikováno v:
Annals of Neurology. 93:604-614
The radiologically isolated syndrome (RIS) represents the earliest detectable pre-clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic intervention in preventing first symptom manifestation at this stage in the di