Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ellen M. Beauchamp"'
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Tables S1-S19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e51f56a5f32d341b5c2e51674ff765e
https://doi.org/10.1158/2643-3230.22543738
https://doi.org/10.1158/2643-3230.22543738
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Clonal hematopoiesis results from somatic mutations in cancer driver genes in hematopoietic stem cells. We sought to identify novel drivers of clonal expansion using an unbiased analysis of sequencing data from 84,683 persons and identified common mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55289da636eb1db4ca374a11330f8d09
https://doi.org/10.1158/2643-3230.c.6550390
https://doi.org/10.1158/2643-3230.c.6550390
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Figures S1-S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08370a390f5261d6d0398c3791fc3597
https://doi.org/10.1158/2643-3230.22543741.v1
https://doi.org/10.1158/2643-3230.22543741.v1
Autor:
Peter S. Hammerman, Matthew Meyerson, Kwok-kin Wong, Adam J. Bass, Nathanael S. Gray, Chunxiao Xu, Li Tan, Austin M. Dulak, Brittany A. Woods, Ellen M. Beauchamp
PDF - 36KB, Sensitivity of NCI-H2286 and NCI-H2286-DR to MEK inhibitor is unchanged in the presence or absence of dasatinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2c1b2bd6c051ab62d2ca3b0d741f1d
https://doi.org/10.1158/1535-7163.22499911
https://doi.org/10.1158/1535-7163.22499911
Autor:
Peter S. Hammerman, Matthew Meyerson, Kwok-kin Wong, Adam J. Bass, Nathanael S. Gray, Chunxiao Xu, Li Tan, Austin M. Dulak, Brittany A. Woods, Ellen M. Beauchamp
PDF - 69KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854916457af081ee62a9e9ec9b99cf95
https://doi.org/10.1158/1535-7163.22499908
https://doi.org/10.1158/1535-7163.22499908
Autor:
Peter S. Hammerman, Matthew Meyerson, Kwok-kin Wong, Adam J. Bass, Nathanael S. Gray, Chunxiao Xu, Li Tan, Austin M. Dulak, Brittany A. Woods, Ellen M. Beauchamp
PDF - 96KB, Dasatinib treatment results in dephosphorylation of DDR2 in parental lines but not in parental lines expressing DDR2 T654I. This dephosphorylation is also observed following dasatinib treatment in NCI-H2286-DR but not in HCC-366-DR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017656506471435cc75d5cefa9d6dae1
https://doi.org/10.1158/1535-7163.22499917.v1
https://doi.org/10.1158/1535-7163.22499917.v1
Autor:
Kwok-Kin Wong, Glenn Dranoff, Peter S. Hammerman, Gordon J. Freeman, Scott J. Rodig, Lynette M. Sholl, Takeshi Shimamura, Geoffrey I. Shapiro, D. Neil Hayes, Matthew Meyerson, Pasi A. Janne, Travis J. Cohoon, Margaret Soucheray, Jacob B. Reibel, Mohit Butaney, Peter E. Fecci, Matthew D. Wilkerson, Trevor J. Pugh, Ellen M. Beauchamp, Andrew D. Cherniack, Oliver R. Mikse, Camilla L. Christensen, Jeremy H. Tchaicha, Abigail Altabef, Julian Carretero, Shohei Koyama, Esra A. Akbay
PDF file 2020K, Supplementary figures 1-11. For the mouse experiments tumor bearing lungs were classified as mildly sick and severely sick based on the tumor burden as determined by right lung lobe weights. Oncogene induced immunosuppressive environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae04d09fa1c83e0baed34f2e4825036
https://doi.org/10.1158/2159-8290.22530267
https://doi.org/10.1158/2159-8290.22530267
Autor:
Peter S. Hammerman, Matthew Meyerson, Kwok-kin Wong, Adam J. Bass, Nathanael S. Gray, Chunxiao Xu, Li Tan, Austin M. Dulak, Brittany A. Woods, Ellen M. Beauchamp
PDF - 61KB, Ectopic expression of IL6ST A664S or RNAi-mediated knockdown of EphA7 do not lead to a change in dasatinib sensitivity in NCI-H2286.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38df67444b2edd08e2d4881d2e9dc9ed
https://doi.org/10.1158/1535-7163.22499914
https://doi.org/10.1158/1535-7163.22499914
Autor:
Kwok-Kin Wong, Glenn Dranoff, Peter S. Hammerman, Gordon J. Freeman, Scott J. Rodig, Lynette M. Sholl, Takeshi Shimamura, Geoffrey I. Shapiro, D. Neil Hayes, Matthew Meyerson, Pasi A. Janne, Travis J. Cohoon, Margaret Soucheray, Jacob B. Reibel, Mohit Butaney, Peter E. Fecci, Matthew D. Wilkerson, Trevor J. Pugh, Ellen M. Beauchamp, Andrew D. Cherniack, Oliver R. Mikse, Camilla L. Christensen, Jeremy H. Tchaicha, Abigail Altabef, Julian Carretero, Shohei Koyama, Esra A. Akbay
PDF file 306K, MRI tumor volume quantification, lists for all the antibodies used in the experiments, gating method for Flow cytometry analysis, and supplementary references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfbbb2a9ce595531c86667cde1572ad
https://doi.org/10.1158/2159-8290.22530261.v1
https://doi.org/10.1158/2159-8290.22530261.v1
Autor:
Kwok-Kin Wong, Glenn Dranoff, Peter S. Hammerman, Gordon J. Freeman, Scott J. Rodig, Lynette M. Sholl, Takeshi Shimamura, Geoffrey I. Shapiro, D. Neil Hayes, Matthew Meyerson, Pasi A. Janne, Travis J. Cohoon, Margaret Soucheray, Jacob B. Reibel, Mohit Butaney, Peter E. Fecci, Matthew D. Wilkerson, Trevor J. Pugh, Ellen M. Beauchamp, Andrew D. Cherniack, Oliver R. Mikse, Camilla L. Christensen, Jeremy H. Tchaicha, Abigail Altabef, Julian Carretero, Shohei Koyama, Esra A. Akbay
PDF file 92K, Legends to supplementary figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947824d181f1754c4d28f57186bca84f
https://doi.org/10.1158/2159-8290.22530270
https://doi.org/10.1158/2159-8290.22530270