Výsledky vyhledávání - "Ellen Luecke"

Akademický článek

Incorporating end-users’ voices into the development of an implant for HIV prevention: a discrete choice experiment in South Africa and Zimbabwe

Autor: Erica N. Browne, Kgahlisho Manenzhe, Wanzirai Makoni, Sikhanyisiwe Nkomo, Imelda Mahaka, Khatija Ahmed, Mary Kate Shapley-Quinn, Tozoe Marton, Ellen Luecke, Leah Johnson, Ariane van der Straten, Alexandra M. Minnis

Publikováno v: BMC Women's Health, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Background Input from end-users during preclinical phases can support market fit for new HIV prevention technologies. With several long-acting pre-exposure prophylaxis (PrEP) implants in development, we aimed to understand young women’s pr

Externí odkaz: https://doaj.org/article/361b57f6b1284953bae28d57e8d02b99

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Akademický článek

Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability

Autor: Mary Kate Shapley-Quinn, Mei Song, Beatrice A. Chen, Brid Devlin, Ellen Luecke, Jill Brown, Diana L. Blithe, Sharon L. Achilles, Ariane van der Straten

Publikováno v: Frontiers in Reproductive Health, Vol 5 (2023)

IntroductionWith high concurrent global rates of HIV incidence and unintended pregnancy, there is a need to provide options beyond condoms to enable users to simultaneously prevent HIV acquisition and pregnancy. Multiple vaginal rings are in developm

Externí odkaz: https://doaj.org/article/9a51de1c28e844e981254d32573e320e

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Akademický článek

Pharmacokinetic Modeling to Guide Preclinical Development of an Islatravir-Eluting Reservoir-Style Biodegradable Implant for Long-Acting HIV PrEP

Autor: Talisa S. Kinsale, Mackenzie L. Cottrell, Linying Li, Rhonda Brand, Greg Gatto, Ellen Luecke, Chasity Norton, Archana Krovi, Julie B. Dumond, Gauri Rao, Shekhar Yeshwante, Brian Van Horne, Ariane Van Der Straten, Angela D. M. Kashuba, Leah M. Johnson

Publikováno v: Pharmaceutics, Vol 16, Iss 2, p 201 (2024)

Long-acting injectable cabotegravir is more effective than daily oral PrEP at preventing HIV transmission due to improved adherence, but requires bi-monthly large-volume intramuscular injections. Subcutaneous (SC) contraceptive implants can be formul

Externí odkaz: https://doaj.org/article/5e3b180f2a7545f595dc9df71e45e098

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Akademický článek

Prospective acceptability of a multipurpose technology (MPT) implant in preclinical development to prevent HIV and unplanned pregnancy: Qualitative insights from women end users and health care providers in South Africa and Zimbabwe.

Autor: Sikhanyisiwe Nkomo, Wanzirai Makoni, Mary Kate Shapley-Quinn, Ellen Luecke, Enough Mbatsane, Kgahlisho Manenzhe, Khatija Ahmed, Leah M Johnson, Imelda Mahaka, Ariane van der Straten

Publikováno v: PLoS ONE, Vol 18, Iss 5, p e0285711 (2023)

BackgroundGiven the high rates of both HIV and unintended pregnancies in sub-Saharan Africa, the SCHIELD program aims to develop a multipurpose technology implant for HIV and pregnancy prevention. An end-user evaluation was undertaken with young wome

Externí odkaz: https://doaj.org/article/0253a78616654e37a4325316f86392a2

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Akademický článek

Impact and experience of participant engagement activities in supporting dapivirine ring use among participants enrolled in the phase III MTN-020/ASPIRE study

Publikováno v: BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background Low adherence to investigational products can negatively impact study outcomes, limiting the ability to demonstrate efficacy. To continue advancing potential new HIV prevention technologies, efforts are needed to improve adherence

Externí odkaz: https://doaj.org/article/c42e11a6e8a640d9b0d026c07dfa4e70

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Acceptability and Preference for 3-Month Versus 1-Month Vaginal Rings for HIV-1 Risk Reduction Among Participants in a Phase 1 Trial

Autor: Theresa Wagner, Ariane van der Straten, Clara P Dominguez Islas, Barbara S. Mensch, Ellen Luecke, Craig J. Hoesley, Sarah T. Roberts, Albert Y. Liu, Tara McClure, Imogen Hawley, Jeanna M. Piper

Publikováno v: Journal of Women's Health. 31:1029-1039

Background: The monthly dapivirine vaginal ring provides partial protection against HIV, and a longer duration ring may reduce user burden and improve adherence. We examined acceptability and prefe...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67237f089a1012d37e1754b15bad401
https://doi.org/10.1089/jwh.2021.0121

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Acceptability of the Dapivirine Vaginal Ring in Postmenopausal US Women

Autor: Mary Kate, Shapley-Quinn, Nicole, Laborde, Ellen, Luecke, Craig, Hoesley, Robert A, Salata, Sherri, Johnson, Annalene, Nel, Lydia, Soto-Torres, Beatrice A, Chen, Ariane, van der Straten

Publikováno v: AIDS Patient Care and STDs. 36:97-105

For women in the United States who remain sexually active beyond child-bearing years, susceptibility to HIV infection remains, yet condom use is low. We assessed acceptability of the dapivirine vaginal ring (ring) among 96 postmenopausal US women enr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b15288217f5e4a3812e651c382992c
https://doi.org/10.1089/apc.2022.0002

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Ring-ing in the Future: Participant and Male Partner Perspectives Regarding Future Use of the Dapivirine Vaginal Ring for HIV Prevention

Autor: Krishnaveni, Reddy, Florence, Mathebula, Ariana, Katz, Ellen, Luecke, Siyanda, Tenza, Thesla, Palanee-Phillips, Morgan, Garcia, Leila E, Mansoor, Sarita, Naidoo, Neetha, Morar, Miria, Chitukuta, Mercy, Tsidya, Elizabeth T, Montgomery

Publikováno v: AIDS Behav

Women account for a disproportionate percentage of new HIV infections in sub-Saharan Africa indicating a need for female-initiated HIV prevention options congruent with their lifestyles. The dapivirine vaginal ring for HIV prevention is one such opti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9a766cc62d5b26dd10f1537d844047
https://doi.org/10.1007/s10461-021-03542-z

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