Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ellen Loyens"'
Publikováno v:
Vrije Universiteit Brussel
The possible involvement of oxytocin (OT) in the generation of seizures has not received a lot of attention in the past, although generalized epileptic convulsions were observed in humans following intravenous OT infusion. We here aimed to investigat
Autor:
Wilhelmus Drinkenburg, Ann Massie, Ellen Loyens, Yvette Michotte, Dieder Moechars, Ilse Julia Smolders, Anneleen Schallier
Publikováno v:
Neurochemistry International. 55:41-44
Glutamate, the most abundant excitatory neurotransmitter in the central nervous system, is well known to be implicated in epileptic seizures. Therefore, impairments in glutamate transport could have an involvement in the mechanism of epileptogenesis.
Autor:
Véronique Bernard, Najat Aourz, Dimitri De Bundel, Patrick Vanderheyden, Vincent El Ghouzzi, Jeanelle Portelli, Jessica Coppens, Pascal Dournaud, Zsolt Csaba, Foteini Kiagiadaki, Guilan Vodjdani, Sophie Lebon, Stéphane Peineau, Siew Yeen Chai, Ilse Julia Smolders, Kyriaki Thermos, Laura Walrave, Graham L. Collingridge, Assia Fafouri, Stéphane Auvin, Pierre Gressens, Ellen Loyens
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/JNEUROSCI.0476-15.2015⟩
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/jneurosci.0476-15.2015⟩
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/JNEUROSCI.0476-15.2015⟩
Journal of Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/JNEUROSCI.0476-15.2015⟩
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/jneurosci.0476-15.2015⟩
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (34), pp.11960-11975. ⟨10.1523/JNEUROSCI.0476-15.2015⟩
Within the hippocampus, the major somatostatin (SRIF) receptor subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where it modulates neuronal activity. Following agonist exposure, this receptor rapidly internaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f8cd806d123bc2298265ff939df318
https://hdl.handle.net/20.500.14017/1bd0866a-ed91-4af7-946e-6d10887e64dc
https://hdl.handle.net/20.500.14017/1bd0866a-ed91-4af7-946e-6d10887e64dc
In the management of epilepsy, AT 1 receptor antagonists have been suggested as an additional treatment strategy. A hyperactive brain angiotensin (Ang) II system and upregulated AT 1 receptors are implicated in the cerebrovascular alterations in a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6dbcc10f237232152c930fbac8f5da
https://doi.org/10.1016/j.yebeh.2015.03.021
https://doi.org/10.1016/j.yebeh.2015.03.021
Autor:
Ellen Loyens, Dimitri De Bundel, Patrick Vanderheyden, Yvette Michotte, Paul R. Gard, Heidi Demaegdt, Siew Yeen Chai, Ilse Julia Smolders
Publikováno v:
Vrije Universiteit Brussel
Oxytocin is a neuromodulator with antidepressant-like effects. In vitro, oxytocin is rapidly cleaved by insulin-regulated aminopeptidase (IRAP). Oxytocin metabolites are known to exert strong central activities that are different from the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e275828cea2cfa38f24683e0b8f6d0
https://hdl.handle.net/20.500.14017/9d56b237-9cdf-4e4e-86da-22a4be1ee9bc
https://hdl.handle.net/20.500.14017/9d56b237-9cdf-4e4e-86da-22a4be1ee9bc
Autor:
Denis Vivien, Maria De Mol, Peter Carmeliet, Kristof Anthonis, Yvette Michotte, Stefan Vinckier, Claire Meissirel, Mieke Dewerchin, Paul A. Salin, Alain Chédotal, Pierre De Rossi, Véronique Rogemond, Wim Robberecht, Jérôme Honnorat, Ellen Loyens, Cathy Coulon, Inmaculada Segura, Nicole Thomasset, Ilse Julia Smolders, Dietmar Schmucker, Karel Dassonville, Bérangère Deleglise, Salvatore Oliviero, Pieter Vanden Berghe, Ludo Van Den Bosch, Ellen Knevels, Naura Chounlamountri, Carine Ali, Carmen Ruiz de Almodovar, Thomas Voets
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (33), pp.13782-13787. ⟨10.1073/pnas.1100341108⟩
Vrije Universiteit Brussel
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (33), pp.13782-13787. ⟨10.1073/pnas.1100341108⟩
Vrije Universiteit Brussel
NMDA type glutamate receptors (NMDARs) are best known for their role in synaptogenesis and synaptic plasticity. Much less is known about their developmental role before neurons form synapses. We report here that VEGF, which promotes migration of gran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1814a428eaeaebedfffbbfc446b80f29
http://www.pnas.org/cgi/pmidlookup?view=long&pmid=21804034
http://www.pnas.org/cgi/pmidlookup?view=long&pmid=21804034
Autor:
Hideyo Sato, Ruani N Fernando, Ellen Loyens, Shiro Bannai, Anneleen Schallier, Katia Vermoesen, Ilse Julia Smolders, Hirohisa Miyashita, Yvette Michotte, Joeri Van Liefferinge, Ann Massie, Dimitri De Bundel
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(15)
System xc−exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular glutamate release. We report that mice lacking the specific xCT subunit of system xc−(xCT−
Autor:
Anneleen Schallier, Dimitri De Bundel, Ellen Loyens, Ruani Fernando, Hideyo Sato, Yvette Michotte, Ann Massie, Ilse Smolders
Publikováno v:
Vrije Universiteit Brussel
System xc- exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and regulating extracellular glutamate levels. We used mice lacking the xCT subunit of system xc- (xCT-/-) to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4a644594954ce8f878e4a19b0003f784
https://biblio.vub.ac.be/vubir/involvement-of-the-cystineglutamate-antiporter-in-hippocampal-functioning-implications-for-seizure-sensitivity(f4445150-9e81-4257-80b1-4aa15082faae).html
https://biblio.vub.ac.be/vubir/involvement-of-the-cystineglutamate-antiporter-in-hippocampal-functioning-implications-for-seizure-sensitivity(f4445150-9e81-4257-80b1-4aa15082faae).html
Autor:
Ellen Loyens, Peter Paul De Deyn, Yvette Michotte, Alex Michotte, Anneleen Schallier, Debby Van Dam, Ann Massie, Ilse Julia Smolders
Publikováno v:
Journal of Alzheimer's disease : JAD. 24(2)
Using 8- and 18-month-old AβPP23 mice, we investigated the involvement of high-affinity glutamate transporters (GLAST, GLT-1, EAAC1), vesicular glutamate transporters (VGLUT1-3) and xCT, the specific subunit of system x(c)⁻, in Alzheimer's disease
Autor:
Anneleen Schallier, Ilse Smolders, Debby Van Dam, Ellen Loyens, Peter De Deyn, Alex Michotte, Yvette Michotte, Ann Massie
Publikováno v:
Vrije Universiteit Brussel
Introduction: Alzheimer's disease (AD) is an irreversible neurodegenerative disorder causing dementia and is characterized by neuronal loss as well as the formation of amyloid plaques and neurofibrillary tangles. To date, few drugs are available and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1dbc982deb01fa753a714cc31969b19f
https://biblio.vub.ac.be/vubir/region-and-agespecific-changes-in-glutamate-transport-in-the-app23-mouse-model(098bd08e-edda-40a1-8ba9-674bf3832e0d).html
https://biblio.vub.ac.be/vubir/region-and-agespecific-changes-in-glutamate-transport-in-the-app23-mouse-model(098bd08e-edda-40a1-8ba9-674bf3832e0d).html