Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ellen L. W. Kittler"'
Autor:
Li Xie, Claude Gazin, Sung Mi Park, Lihua J Zhu, Marie-anne Debily, Ellen L W Kittler, Maria L Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R Green
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003151 (2012)
Numerous genetic and epigenetic alterations render cancer cells selectively dependent on specific genes and regulatory pathways, and represent potential vulnerabilities that can be therapeutically exploited. Here we describe an RNA interference (RNAi
Externí odkaz:
https://doaj.org/article/11c6cc1ae4eb4d4cb2683ba84f2eb531
Autor:
Jonathan A. Epstein, Ellen L. W. Kittler, Monique W. Bruinsma, Maria L. Zapp, Mark A. Bayfield, Samuel A. Hasson, Richard J. Maraia, Denise Rockwell, Dagmar Bacikova, Daniel Ahmad, James R. Iben
Publikováno v:
Nucleic Acids Research
We used a genetic screen based on tRNA-mediated suppression (TMS) in a Schizosaccharomyces pombe La protein (Sla1p) mutant. Suppressor pre-tRNA(Ser)UCA-C47:6U with a debilitating substitution in its variable arm fails to produce tRNA in a sla1-rrm mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b085bc44ec93b432bf33dd352497c94e
https://doi.org/10.1093/nar/gkr066
https://doi.org/10.1093/nar/gkr066
Autor:
Vasily V. Vagin, Ellen L. W. Kittler, Carla Andrea Klattenhoff, William E. Theurkauf, Nadine Schulz, Maria L. Zapp, Monika Syrzycka, Zhiping Weng, Phillip D. Zamore, Hervé Seitz, Michael D. Horwich, Barry M. Honda, Shengmei Ma, Chengjian Li, Soohyun Lee, Jia Xu, Hualin Xi
Publikováno v:
Cell. 137(3):509-521
Piwi-interacting RNAs (piRNAs) silence transposons in the germ line of animals. They are thought to derive from long primary transcripts spanning transposon-rich genomic loci, “piRNA clusters.” piRNAs are proposed to direct an auto-amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f175892067c7a19e1161b05f2395c065
Autor:
Ellen L. W. Kittler, Tingting Du, Soohyun Lee, Megha Ghildiyal, Jia Xu, Maria L. Zapp, Hervé Seitz, Phillip D. Zamore, Michael D. Horwich, Zhiping Weng, Chengjian Li
Publikováno v:
Science. 320:1077-1081
Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA (dsRNA) as a defense against viral infection. We identified endogenous siRNAs (endo-siRNAs), 21 nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e8357d65de677278607aa8f71f33af
https://doi.org/10.1126/science.1157396
https://doi.org/10.1126/science.1157396
Autor:
Zhong Yu, Nuria Sánchez-Velar, Ellen L. W. Kittler, Maria L. Zapp, Irina E. Catrina, Enyeneama B. Udofia
Publikováno v:
Proceedings of the National Academy of Sciences. 102:4027-4032
An important goal of contemporary HIV type 1 (HIV-1) research is to identify cellular cofactors required for viral replication. The HIV-1 Rev protein facilitates the cytoplasmic accumulation of the intron-containing viral gag-pol and env mRNAs and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7443cb732e797b1dffcdc5bc296f1a49
https://doi.org/10.1073/pnas.0408889102
https://doi.org/10.1073/pnas.0408889102
Autor:
Alexander Fodor, Leonid L. Moroz, Tigran P. Norekian, Krishanu Mukherjee, Eugene Berezikov, Joshua J. Swore, Jonathan P. Rast, David Orion Girardo, Billie J. Swalla, Jonathan V. Sweedler, Claudia E. Mills, Denis A. Reshetov, Victor V. Solovyev, Sohn Dosung, Yelena Bobkova, Inna S. Povolotskaya, Andrey A. Ptitsyn, Tatiana P. Moroz, Evgeny I. Rogaev, Vladimir V. Kapitonov, Mathew R. Citarella, Katherine M. Buckley, Kenneth M. Halanych, Christopher A. Dailey, Ellen L. W. Kittler, Fedor Gusev, Romain Derelle, Fahong Yu, Yuri V. Bobkov, Fyodor A. Kondrashov, Rebecca Bruders, Anastasia P. Grigorenko, Rachel Sanford, Jerzy Jurka, Kevin M. Kocot, Andrea B. Kohn
Publikováno v:
Nature, 510(7503), 109-114.e13. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat. Dipósit de la Recerca de Catalunya
instname
The origins of neural systems remain unresolved. In contrast to other basal metazoans, ctenophores (comb jellies) have both complex nervous and mesoderm-derived muscular systems. These holoplanktonic predators also have sophisticated ciliated locomot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229e5781a629154f3607e78e937fc29c
https://research.rug.nl/en/publications/2e48b063-e233-402a-a692-ca68938289dd
https://research.rug.nl/en/publications/2e48b063-e233-402a-a692-ca68938289dd
Autor:
Michelle E. Debatis, Crittenden Rb, Ellen L. W. Kittler, Peter J. Quesenberry, F. Marc Stewart, Hayley S. Ramshaw, Stefan O. Peters
Publikováno v:
Blood. 90:865-872
Using a murine bone marrow transplantation model, we evaluated the long-term engraftment of retrovirally transduced bone marrow cells in nonmyeloablated hosts. Male bone marrow was stimulated in a cocktail of interleukin-3 (IL-3), IL-6, IL-11, and st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4343dbc247c0896ceddb1012ec868963
https://doi.org/10.1182/blood.v90.2.865
https://doi.org/10.1182/blood.v90.2.865
Publikováno v:
Blood. 87:30-37
In vitro incubation of bone marrow cells with cytokines has been used as an approach to expand stem cells and to facilitate retroviral integration. Expansion of hematopoietic progenitor cells has been monitored by different in vitro assays and in a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131fe086c8b2bac254ca0da9ebcc6c49
https://doi.org/10.1182/blood.v87.1.30.30
https://doi.org/10.1182/blood.v87.1.30.30
Autor:
Helen E. McGrath, Rowena B. Crittenden, Ellen L. W. Kittler, V. K. Kister, Temeles Ds, Peter J. Quesenberry
Publikováno v:
Blood. 79:3168-3178
The “stromal” or adherent cells of long-term murine Dexter explant bone marrow cultures provide the best in vitro model of the bone marrow microenvironment. Colony-stimulating factor-1 (CSF-1) is produced constitutively by these cells and is easi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d37e782f4bd61ee2b480a4c39b716b9c
https://doi.org/10.1182/blood.v79.12.3168.bloodjournal79123168
https://doi.org/10.1182/blood.v79.12.3168.bloodjournal79123168
Autor:
Gulnaz Faskhutdinova, Ellen L. W. Kittler, Anastasia P. Grigorenko, Yuri K. Moliaka, Evgeny I. Rogaev
Publikováno v:
Science (New York, N.Y.). 326(5954)
The "royal disease," a blood disorder transmitted from Queen Victoria to European royal families, is a striking example of X-linked recessive inheritance. Although the disease is widely recognized to be a form of the blood clotting disorder hemophili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc62e3f66e9dfee960c5c1ece2e70a9c
https://pubmed.ncbi.nlm.nih.gov/19815722
https://pubmed.ncbi.nlm.nih.gov/19815722