Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Ellen L Neidle"'
Autor:
Jennifer A Herrmann, Agata Koprowska, Tesa J Winters, Nancy Villanueva, Victoria D Nikityuk, Feini Pek, Elizabeth M Reis, Constancia Z Dominguez, Daniel Davis, Eric McPherson, Staci R Rocco, Cynthia Recendez, Shyla M Difuntorum, Kelly Faeth, Mario D Lopez, Habeeba M Awwad, Rola A Ghobashy, Lauren Cappiello, Ellen L Neidle, Semarhy Quiñones-Soto, Andrew B Reams
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 3 (2022)
AbstractThe controversial theory of adaptive amplification states gene amplification mutations are induced by selective environments where they are enriched due to the stress caused by growth restriction on unadapted cells. We tested this theory with
Externí odkaz:
https://doaj.org/article/aa11054105874419b904cc5f189412be
Autor:
Anita Singh, Stacy R. Bedore, Nilesh K. Sharma, Sarah A. Lee, Mark A. Eiteman, Ellen L. Neidle
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Background Lignocellulosic biomass is an attractive, inexpensive source of potentially fermentable sugars. However, hydrolysis of lignocellulose results in a complex mixture containing microbial inhibitors at variable composition. A single m
Externí odkaz:
https://doaj.org/article/410788e4ae614dd9bf4eb7faa41aff72
Autor:
Sam J. B. Mallinson, Melodie M. Machovina, Rodrigo L. Silveira, Marc Garcia-Borràs, Nathan Gallup, Christopher W. Johnson, Mark D. Allen, Munir S. Skaf, Michael F. Crowley, Ellen L. Neidle, Kendall N. Houk, Gregg T. Beckham, Jennifer L. DuBois, John E. McGeehan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Catabolizing lignin-derived aromatic compounds requires an aryl-O-demethylation step. Here the authors present the structures of GcoA and GcoB, a cytochrome P450-reductase pair that catalyzes aryl-O-demethylations and show that GcoA displays broad su
Externí odkaz:
https://doaj.org/article/794b35c1169a406b89565b7b8ae40208
Autor:
Stacy R. Bedore, Ellen L. Neidle, Isabel Pardo, Jin Luo, Alyssa C. Baugh, Chantel V. Duscent-Maitland, Melissa P. Tumen-Velasquez, Ville Santala, Suvi Santala
Publikováno v:
Genome Engineering ISBN: 9780128235409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f6c11a487f944a403f9eef01cc34f5b
https://doi.org/10.1016/bs.mim.2023.01.002
https://doi.org/10.1016/bs.mim.2023.01.002
Autor:
Isabel Pardo, Stacy R. Bedore, Melissa P. Tumen-Velasquez, Chantel V. Duscent-Maitland, Alyssa C. Baugh, Suvi Santala, Ellen L. Neidle
Publikováno v:
Genome Engineering ISBN: 9780128235409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885227c850b814062e270cdc4b964e72
https://doi.org/10.1016/bs.mim.2023.01.001
https://doi.org/10.1016/bs.mim.2023.01.001
Autor:
Stacy R. Bedore, Alicia L. Schmidt, Lauren E. Slarks, Chantel V. Duscent-Maitland, Kathryn T. Elliott, Silke Andresen, Flavia G. Costa, R. Sophia Weerth, Melissa P. Tumen-Velasquez, Lindsey N. Nilsen, Cassandra E. Dean, Anna C. Karls, Timothy R. Hoover, Ellen L. Neidle
Publikováno v:
Appl Environ Microbiol
The regulated uptake and consumption of d-amino acids by bacteria remain largely unexplored, despite the physiological importance of these compounds. Unlike other characterized bacteria, such as Escherichia coli, which utilizes only l-Asp, Acinetobac
Autor:
Ramesh K. Jha, Molly Gaddis, Emily A. McIntyre, Ellen L. Neidle, Felicia Bratti, William E. Michener, Christopher W. Johnson, Ryan E. Bermel, Taraka Dale, Isabel Pardo, Gregg T. Beckham
Publikováno v:
Metabolic Engineering. 62:260-274
Microbial terephthalic acid (TPA) catabolic pathways are conserved among the few bacteria known to turnover this xenobiotic aromatic compound. However, to date there are few reported cases in which this pathway has been successfully expressed in hete
Publikováno v:
Appl Environ Microbiol
Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of microbial hosts. Evolved strains typically contain numerous mutations that can be revealed by whole-genome sequencing. However, determining the contribution of spe
Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of microbial hosts. Evolved strains typically contain numerous mutations that can be revealed by whole-genome sequencing. However, determining the contribution of spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d54d9d1efde022a673d1c4854edc18e
https://doi.org/10.1101/2021.09.07.459243
https://doi.org/10.1101/2021.09.07.459243
Autor:
Sarah A. Lee, Jeffrey G. Linger, Melissa P Tumen-Velasquez, Ellen L. Neidle, Mark A. Eiteman, Gregg T. Beckham, Payal Khanna, Emily M. Fulk, Christopher W. Johnson, Ahmed Alaa Ashraf Mahmoud, Graham Dominick, Alicia L. Schmidt
Publikováno v:
Proceedings of the National Academy of Sciences. 115:7105-7110
Experimental evolution is a critical tool in many disciplines, including metabolic engineering and synthetic biology. However, current methods rely on the chance occurrence of a key step that can dramatically accelerate evolution in natural systems,