Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Ellen Kuhl"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The lack of sex-specific cardiovascular disease criteria contributes to the underdiagnosis of women compared to that of men. For more than half a century, the Framingham Risk Score has been the gold standard to estimate an individual’s risk of deve
Externí odkaz:
https://doaj.org/article/401c2195c6564bb189baf05d22c111b6
Publikováno v:
Brain Multiphysics, Vol 4, Iss , Pp 100066- (2023)
The soft tissue of the brain deforms in response to external stimuli, which can lead to traumatic brain injury. Constitutive models relate the stress in the brain to its deformation and accurate constitutive modeling is critical in finite element sim
Externí odkaz:
https://doaj.org/article/cc790cfbbbc5498d9c11e7b64d512829
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cardiovascular disease in women remains under-diagnosed and under-treated. Recent studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic criteria. While it is widely recognized that the female heart is smaller t
Externí odkaz:
https://doaj.org/article/152ce3faea004578859ab88e07ae0395
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The electrical activity in the heart varies significantly between men and women and results in a sex-specific response to drugs. Recent evidence suggests that women are more than twice as likely as men to develop drug-induced arrhythmia with potentia
Externí odkaz:
https://doaj.org/article/c93c496b46a24f54aad0d7dd0ec90a8f
Publikováno v:
Physical Review Research, Vol 4, Iss 3, p 033125 (2022)
The growth of axons is a key process in neural system development, which relies upon a subtle balance between external mechanical forces and remodeling of cellular constituents. A key problem in the biophysics of axons is therefore to understand the
Externí odkaz:
https://doaj.org/article/50af29a52dcc4be9bd9e41608ef8180a
Autor:
Amelie Schäfer, Mathias Peirlinck, Kevin Linka, Ellen Kuhl, The Alzheimer's Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Amyloid-β and hyperphosphorylated tau protein are known drivers of neuropathology in Alzheimer's disease. Tau in particular spreads in the brains of patients following a spatiotemporal pattern that is highly sterotypical and correlated with subseque
Externí odkaz:
https://doaj.org/article/b4e098baadb04050a9d4f9ca5f31af77
Publikováno v:
Brain Multiphysics, Vol 2, Iss , Pp 100039- (2021)
For more than 25 years, the amyloid hypothesis–the paradigm that amyloid is the primary cause of Alzheimer’s disease–has dominated the Alzheimer’s community. Now, increasing evidence suggests that tissue atrophy and cognitive decline in Alzhe
Externí odkaz:
https://doaj.org/article/d2b10433bdc54aa9a6e3dffb00c6bbb9
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer's disease is associated with the cerebral accumulation of neurofibrillary tangles of hyperphosphorylated tau protein. The progressive occurrence of tau aggregates in different brain regions is closely related to neurodegeneration and cognit
Externí odkaz:
https://doaj.org/article/e305cca4551e4ce8ba74c027a07eed65
Autor:
Travis B Thompson, Pavanjit Chaggar, Ellen Kuhl, Alain Goriely, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008267 (2020)
Neurodegenerative diseases such as Alzheimer's or Parkinson's are associated with the prion-like propagation and aggregation of toxic proteins. A long standing hypothesis that amyloid-beta drives Alzheimer's disease has proven the subject of contempo
Externí odkaz:
https://doaj.org/article/8603566a9dcf4b5b8809064f9a01ee55
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
A critical procedure in diagnosing atrial fibrillation is the creation of electro-anatomic activation maps. Current methods generate these mappings from interpolation using a few sparse data points recorded inside the atria; they neither include prio
Externí odkaz:
https://doaj.org/article/f96249a175624e17bd50ccb5ae280d8d