Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ellen K, LeMosy"'
Autor:
Hannah Neiswender, Ellen K. LeMosy
A highly-conserved extracellular matrix protein, Tinagl1, modulates Wnt, integrin, TGF-β, and EGF-R signalingin vitro,but its significancein vivohas remained in doubt. To bypass possible genetic compensation by an ortholog encoded exclusively in mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9c60b409e40f46205a6b28e3855bc9
https://doi.org/10.1101/2020.06.05.136747
https://doi.org/10.1101/2020.06.05.136747
Publikováno v:
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 54(4)
ObjectiveTinagl1 has a weak genetic association with craniosynostosis, but its functions in cartilage and bone development are unknown. Knockdown of Tinagl1 in zebrafish embryos allowed an initial characterization of its potential effects on craniofa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb7b45ff63439a152403308b6227364
https://pubmed.ncbi.nlm.nih.gov/27243669
https://pubmed.ncbi.nlm.nih.gov/27243669
Publikováno v:
Protein & Peptide Letters. 16:437-443
The Drosophila proteases Gastrulation Defective and Snake function in embryonic polarity establishment and bind heparin, a surrogate for anionic species present in the extracellular matrix. Here we demonstrate binding of GD, but not Snake, to anionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8e9d0f7db3e7dd8ab7d397ec4b0ed8
https://doi.org/10.2174/092986609787848135
https://doi.org/10.2174/092986609787848135
Publikováno v:
Developmental Dynamics. 237:3927-3939
Integrins are heterodimeric transmembrane receptors that modulate cell adhesion, migration, and signaling. Multiple integrin chains contribute to development and morphogenesis of a given tissue. Here, we analyze the expression of Drosophila integrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63fbf5f7ee83651d1ad22691e8e95bf
https://doi.org/10.1002/dvdy.21802
https://doi.org/10.1002/dvdy.21802
Autor:
Eric Miller, Ellen K. LeMosy, Maggie Elalayli, Daniel Sherling, Xutong Sun, Mazen Fakhouri, Lance Wells, Jacklyn D. Hall
Publikováno v:
Developmental Biology. 293(1):127-141
The Drosophila eggshell provides an in vivo model system for extracellular matrix assembly, in which programmed gene expression, cell migrations, extracellular protein trafficking, proteolytic processing, and cross-linking are all required to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10610e58cc8ed8eb008d206c9be0e072
Autor:
Thierry Rose, Dolly Banerjee-Roy, Angelene M. Cantwell, Ellen K. LeMosy, Enrico Di Cera, James B. Skeath
Publikováno v:
Journal of Biological Chemistry. 278:11320-11330
Three-dimensional models of the catalytic domains of Nudel (Ndl), Gastrulation Defective (Gd), Snake (Snk), and Easter (Ea), and their complexes with substrate suggest a possible organization of the enzyme cascade controlling the dorsoventral fate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc13b7c39ecca47816382f89126206a
https://doi.org/10.1074/jbc.m211820200
https://doi.org/10.1074/jbc.m211820200
Publikováno v:
Proceedings of the National Academy of Sciences. 98:5055-5060
Dorsoventral patterning of the Drosophila embryo is initiated by a ventralizing signal. Production of this signal requires the serine proteases Gastrulation Defective (GD), Snake, and Easter, which genetic studies suggest act sequentially in a cascad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8386a3c0eb0a4f71e8b7df3c3f0a55ff
https://doi.org/10.1073/pnas.081026598
https://doi.org/10.1073/pnas.081026598
Publikováno v:
Genetics. 154:247-257
The nudel gene of Drosophila is maternally required both for structural integrity of the egg and for dorsoventral patterning of the embryo. It encodes a structurally modular protein that is secreted by ovarian follicle cells. Genetic and molecular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df6eb7c5a673b6506d1ff187b589cc7
https://doi.org/10.1093/genetics/154.1.247
https://doi.org/10.1093/genetics/154.1.247
Publikováno v:
Development. 125:4045-4053
The establishment of embryonic dorsoventral polarity in Drosophila depends on a signaling mechanism in which the signal for ventral development is locally produced. This mechanism requires the activity of the nudel gene in ovarian follicle cells, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb90e49d5704c78fb7aa6ebbfd1c77be
https://doi.org/10.1242/dev.125.20.4045
https://doi.org/10.1242/dev.125.20.4045