Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ellen J van Gastel"'
Autor:
Anke Schilhabel, Monika Szczepanowski, Ellen J. van Gastel-Mol, Janina Schillalies, Jill Ray, Doris Kim, Michaela Nováková, Isabel Dombrink, Vincent H. J. van der Velden, Sebastian Boettcher, Monika Brüggemann, Michael Kneba, Jacques J. M. van Dongen, Anton W. Langerak, Matthias Ritgen
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Detection of patient- and tumor-specific clonally rearranged immune receptor genes using real-time quantitative (RQ)-PCR is an accepted method in the field of precision medicine for hematologic malignancies. As individual primers are needed for each
Externí odkaz:
https://doaj.org/article/415dfc4529dd43d7913e3552a40d5ead
Autor:
Andrea Patriarca, Marco Montillo, Niki Stavroyianni, Claudia Haferlach, Lesley-Ann Sutton, Livio Trentin, Franco Fais, Raphael Sandaltzopoulos, Arnon P. Kater, Anton W. Langerak, Marine Armand, Davide Rossi, Diane F. Jelinek, Davide Bagnara, Lydia Scarfò, Andreas Agathangelidis, Krzysztof Giannopoulos, Eugen Tausch, Andrey Sudarikov, Silvio Veronese, Salem H. Alshemmari, B V Biderman, Zadie Davis, Chrysoula Belessi, Lisa Bonello, Achilles Anagnostopoulos, Gerlinde Mitterbauer-Hohendanner, David Oscier, Sofia Kossida, Lone Bredo Pedersen, Paolo Ghia, Csaba Bödör, Christian Brieghel, Andrea Visentin, Véronique Giudicelli, Matthias Ritgen, Panagiotis Panagiotidis, Panagiotis Baliakas, Stephan Stilgenbauer, Ellen J van Gastel, Renee C. Tschumper, Christiane Pott, Frederic Davi, Katerina Gemenetzi, Valentina Guido, Elias Campo, Gianluca Gaidano, Irina Panovska, Sabine Jeromin, Karla Plevová, Kostas Stamatopoulos, Kamila Brázdilová, Maria Karypidou, Alba Navarro, Christof W. Schneider, Theodoros Moysiadis, Larry Mansouri, Darko Antic, Cristina Tresoldi, Constance Baer, Šárka Pospíšilová, Maria Roumelioti, Katrina Vanura, Xiao-Jie Yan, Hana Skuhrová Francová, Richard Rosenquist, Blanca Espinet, Paola Francia di Celle, Monica Facco, Paul Costeas, Michael Hallek, Carsten Utoft Niemann, Teodora Karan-Djurasevic, Manja Meggendorfer, Kirsten Fischer, Aleksandar Dimovski, Letizia Foroni, Marie-Paule Lefranc, Mark Catherwood, Anne de Septenville, Anastasia Chatzidimitriou, Sarah Lawless, Nicholas Chiorazzi
Publikováno v:
ERIC, the European Research Initiative on CLL 2021, ' Higher-order connections between stereotyped subsets : implications for improved patient classification in CLL ', Blood, vol. 137, no. 10, pp. 1365-1376 . https://doi.org/10.1182/blood.2020007039
Blood, 137(10), 1365-1376. American Society of Hematology
Blood
Blood, 137(10), 1365-1376. American Society of Hematology
Blood
Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B-cell receptor (BcR) immunoglobulins. Patients in certain major stereotyped subsets often display remarkably consistent cl
Autor:
Bianca Blom, Martie C.M. Verschuren, Mirjam H.M. Heemskerk, Arjen Q. Bakker, Ellen J. van Gastel-Mol, Ingrid L.M. Wolvers-Tettero, Jacques J.M. van Dongen, Hergen Spits
Publikováno v:
Blood. 93:3033-3043
Recent studies have identified several populations of progenitor cells in the human thymus. The hematopoietic precursor activity of these populations has been determined. The most primitive human thymocytes express high levels of CD34 and lack CD1a.
Autor:
Lone Bredo Pedersen, Frederic Davi, Nikos Darzentas, Andreas Agathangelidis, Anton W. Langerak, Boris Tichy, Chrysoula Belessi, Karin E. Smedby, Lisa Bonello, Šárka Pospíšilová, Richard Rosenquist, Kostas Stamatopoulos, Ellen J. van Gastel-Mol, Nicola Cahill, Achilles Anagnostopoulos, Xiao-Jie Yan, Athanasios Tsaftaris, Christian H. Geisler, Agnieszka Janus, Charles C. Chu, Xavier Brochet, Cristina Tresoldi, Marie-Paule Lefranc, Hélène Merle-Béral, Gunnar Juliusson, Nikolaos Laoutaris, David Oscier, Jesper Jurlander, Paola Francia di Celle, Paolo Ghia, Fiona Murray, Anastasia Hadzidimitriou, Letizia Foroni, Zadie Davis, Nicholas Chiorazzi, Véronique Giudicelli
Publikováno v:
Blood, 119(19), 4467-4475. American Society of Hematology
Mounting evidence indicates that grouping of chronic lymphocytic leukemia (CLL) into distinct subsets with stereotyped BCRs is functionally and prognostically relevant. However, several issues need revisiting, including the criteria for identificatio
Autor:
Brenda Verhaaf, King H. Lam, Yorick Sandberg, Anton W. Langerak, Jacques J.M. van Dongen, Ellen J. van Gastel-Mol
To establish the most sensitive and efficient strategy of clonality diagnostics via immunoglobulin and T-cell receptor gene rearrangement studies in suspected lymphoproliferative disorders, we evaluated 300 samples (from 218 patients) submitted conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee067b9962a08e1ac5c217566263c5fa
https://europepmc.org/articles/PMC1888492/
https://europepmc.org/articles/PMC1888492/
Autor:
Anneke de Torbal, Ulrich Jäger, Anton W. Langerak, Brenda Verhaaf, Ellen J. van Gastel-Mol, Bertrand Nadel, Jacques J.M. van Dongen, Ingrid L. M. Wolvers-Tettero
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(6)
In addition to the classical Vκ-Jκ, Vκ-κ deleting element (Kde), and intron-Kde gene rearrangements, atypical recombinations involving Jκ recombination signal sequence (RSS) or intronRSS elements can occur in the Igκ (IGK) locus, as observed in
Autor:
Mirjam, van der Burg, Barbara H, Barendregt, Ellen J, van Gastel-Mol, Talip, Tümkaya, Anton W, Langerak, Jacques J M, van Dongen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(1)
Two polymorphisms of the human Ig(lambda) (IGL) locus have been described. The first polymorphism concerns a single, 2- or 3-fold amplification of 5.4 kb of DNA in the C(lambda)2-C(lambda)3 region. The second polymorphism is the Mcg(-)Ke(+)Oz(-) isot
Autor:
Mirjam van der Burg, Ellen J. van Gastel-Mol, Barbara H. Barendregt, Anton W. Langerak, T. Tümkaya, Jacques J.M. van Dongen
Publikováno v:
Journal of Immunology, 169, 271-276. American Association of Immunologists
Two polymorphisms of the human Ig(lambda) (IGL) locus have been described. The first polymorphism concerns a single, 2- or 3-fold amplification of 5.4 kb of DNA in the C(lambda)2-C(lambda)3 region. The second polymorphism is the Mcg(-)Ke(+)Oz(-) isot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8066fc8959f40b25566158d5799bfc
https://pure.eur.nl/en/publications/2fccdcab-dc88-4895-9b38-46fcef4ba510
https://pure.eur.nl/en/publications/2fccdcab-dc88-4895-9b38-46fcef4ba510
Autor:
Ingrid L. M. Wolvers-Tettero, Monique E. C. M. Oud, Jacques J.M. van Dongen, Anton W. Langerak, Ellen J. van Gastel-Mol
Publikováno v:
Blood, 98, 2456-2465. American Society of Hematology
T-cell receptor (TCR) gene rearrangements are mediated via V(D)J recombination, which is strictly regulated during lymphoid differentiation, most probably through the action of specific transcription factors. Investigated was whether cotransfection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee86020d5c6896837c5e30b753d7e2b
https://pure.eur.nl/en/publications/b9a0b8d7-7ebf-4f75-aeb6-a933680453f8
https://pure.eur.nl/en/publications/b9a0b8d7-7ebf-4f75-aeb6-a933680453f8
Autor:
Nikos Darzentas, Cristina Tresoldi, Frederic Davi, Paola Francia di Celle, Boris Tichy, Karin E. Smedby, Xavier Brochet, Kostas Stamatopoulos, Athanasios Tsaftaris, Zadie Davis, Achilles Anagnostopoulos, Paolo Ghia, Agnieszka Janus, Šárka Pospíšilová, David Oscier, Gunnar Juliusson, Nikolaos Laoutaris, Xiao-Jie Yan, Nicola Cahill, Chrysoula Belessi, Letizia Foroni, Fiona Murray, Marie-Paule Lefranc, Richard Rosenquist, Ellen J van Gastel, Lone Bredo Pedersen, Anton W. Langerak, Andreas Agathaggelidis, Charles C. Chu, Anastasia Hadzidimitriou, Jesper Jurlander, Hélène Merle-Béral, Véronique Giudicelli, Nicholas Chiorazzi
Publikováno v:
Blood. 116:43-43
Abstract 43 Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets (clusters) of cases with restricted, “stereotyped” immunoglobulin (IG) variable heavy complementarity-determining region 3 (VH CDR3) sequences within thei