Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ellen J Spartz"'
Autor:
Meagan R. Rollins, Jackson F. Raynor, Ebony A. Miller, Jonah Z. Butler, Ellen J. Spartz, Walker S. Lahr, Yun You, Adam L. Burrack, Branden S. Moriarity, Beau R. Webber, Ingunn M. Stromnes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The currently available transgenic T cell receptor (TCR) models represent high affinity antigen-TCR interactions. Authors here present an alternative approach to target an exogenous TCR into the physiological Trac locus in the germline of mice, which
Externí odkaz:
https://doaj.org/article/f686ccd3ae77471d8e50f4e9b637e5d1
Autor:
Sergio M. Navarro, Victor R. Vakayil, Rafat H. Solaiman, Evan J. Keil, Matthew W. Cohen, Ellen J. Spartz, Christopher J. Tignanelli, James V. Harmon
Publikováno v:
BMC Emergency Medicine, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background We investigated key risk factors for hospital admission related to powered scooters, which are modes of transportation with increasing accessibility across the United States (US). Methods We queried the National Electronic Injury
Externí odkaz:
https://doaj.org/article/b6de546805da4a84874566d32b02ed0b
Autor:
Ellen J. Spartz, Matthew Wheelwright, Tetyana Mettler, Khalid Amin, Nabeel Azeem, Mohamed Hassan, Jacob Ankeny, James V. Harmon
Publikováno v:
Clinical Case Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Gallbladder cancer is a rare but potentially fatal disease. It is often asymptomatic in early stages and is frequently found incidentally or during the workup for benign biliary disease. We present two patients who each had suspicious gallbl
Externí odkaz:
https://doaj.org/article/0d4b346a07be4d70850fd04ae47ba96a
Autor:
Adam L. Burrack, Zoe C. Schmiechen, Michael T. Patterson, Ebony A. Miller, Ellen J. Spartz, Meagan R. Rollins, Jackson F. Raynor, Jason S. Mitchell, Tsuneyasu Kaisho, Brian T. Fife, Ingunn M. Stromnes
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
We investigate how myeloid subsets differentially shape immunity to pancreatic ductal adenocarcinoma (PDA). We show that tumor antigenicity sculpts myeloid cell composition and functionality. Antigenicity promotes accumulation of type 1 dendritic cel
Externí odkaz:
https://doaj.org/article/78e01ca8e9fd4f30a7edc6e8a733121d
Publikováno v:
Diagnostics, Vol 13, Iss 1, p 37 (2022)
Mobile health has the potential to transform the management of chronic illnesses, expanding treatment from a purely clinic-based approach to a more patient-centered delivery of care. For patients with inflammatory bowel disease (IBD), a condition cha
Externí odkaz:
https://doaj.org/article/d6a7934aec144b49a52a0c92150ab40e
Autor:
Adam L. Burrack, Ellen J. Spartz, Meagan R. Rollins, Ebony A. Miller, Maria Firulyova, Eduardo Cruz, Michael F. Goldberg, Iris X. Wang, Hezkiel Nanda, Steven Shen, Konstantin Zaitsev, Ingunn M. Stromnes
Publikováno v:
Cancer Immunology, Immunotherapy. 72:1461-1478
Pancreatic ductal adenocarcinoma (PDA) is a lethal and metastatic malignancy resistant to therapy. Elucidating how pancreatic tumor-specific T cells differentiate and are maintained in vivo could inform novel therapeutic avenues to promote T cell ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a800b3a2978443d4dca76a444b603707
https://doi.org/10.1007/s00262-022-03338-7
https://doi.org/10.1007/s00262-022-03338-7
Autor:
Adam L. Burrack, Ellen J. Spartz, Jackson F. Raynor, Iris Wang, Margaret Olson, Ingunn M. Stromnes
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2140-2155.e6 (2019)
Summary: Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer resistant to immunotherapy. We create a PDA mouse model and show that neoantigen expression is required for intratumoral T cell accumulation and response to immune checkpoint blockade
Externí odkaz:
https://doaj.org/article/432579c464ba4028af08cb056171821b
Autor:
Sunil R. Hingorani, Philip D. Greenberg, Robert H. Pierce, Ellen J. Spartz, Jackson F. Raynor, J. Scott Brockenbrough, Cheryl Black, Patrick Bonson, Ayaka Hulbert, Adam L. Burrack, Ingunn M. Stromnes
Supplementary Figures 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3889d98b8d31697f6a7b46d07e3a0c8
https://doi.org/10.1158/2326-6066.22542532
https://doi.org/10.1158/2326-6066.22542532
Autor:
Sunil R. Hingorani, Philip D. Greenberg, Robert H. Pierce, Ellen J. Spartz, Jackson F. Raynor, J. Scott Brockenbrough, Cheryl Black, Patrick Bonson, Ayaka Hulbert, Adam L. Burrack, Ingunn M. Stromnes
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to therapies, including immune-checkpoint blockade. We investigated two distinct strategies to modulate tumor-associated macrophages (TAM) to enhance cellular therapy targeting m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090cc78bd1afb4f777552df268a76f6b
https://doi.org/10.1158/2326-6066.c.6549967.v1
https://doi.org/10.1158/2326-6066.c.6549967.v1
Autor:
Ellen J Spartz, Mina Estafanos, Reema Mallick, Wolfganag Gaertner, Victor Vakayil, Cyrus Jahansouz, Rishav Aggarwal, Sayeed Ikramuddin, Alexander Khoruts, James V Harmon
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a54f64c72f4e86c9fb86da29c66094d
https://doi.org/10.7759/cureus.34998
https://doi.org/10.7759/cureus.34998