Deep-coverage spatiotemporal proteome of the picoeukaryote Ostreococcus tauri reveals differential effects of environmental and endogenous 24-hour rhythms

Autor: Alessandra Stangherlin, Helen K. Feord, John S. O’Neill, Ellen Grünewald, Gerben van Ooijen, Holly Kay, Sew Y. Peak-Chew, Sergio Gil

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Kay, H, Grünewald, E, Feord, H K, Gil, S, Peak-Chew, S Y, Stangherlin, A, O’Neill, J S & Van Ooijen, G 2021, ' Deep-coverage spatiotemporal proteome of the picoeukaryote ostreococcus tauri reveals differential effects of environmental and endogenous 24-hour rhythms ', Communications biology, vol. 4, no. 1, 1147 . https://doi.org/10.1038/s42003-021-02680-3
Communications Biology

The cellular landscape changes dramatically over the course of a 24 h day. The proteome responds directly to daily environmental cycles and is additionally regulated by the circadian clock. To quantify the relative contribution of diurnal versus circ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8727824ad637ad35a6e4924f0647d61e
https://doaj.org/article/5d1cd59dcc7e47d8a24083d7cbcd5956

Publisher Correction: Methylation deficiency disrupts biological rhythms from bacteria to humans

Autor: Kazuki Fukumoto, P. Lynne Howell, Gerben van Ooijen, Ryoichiro Kageyama, Mayu Yamano, T. Katherine Tamai, Christin Rakers, Kumiko Yoshioka-Kobayashi, Diego A. Golombek, Rika Kojima, Takuya Matsuo, Ralf Stanewsky, Kensuke Kaneko, Hideaki Kakeya, Maria Luísa Jabbur, Carl Hirschie Johnson, Melisa L. Lamberti, Stephanie Tammam, David Whitmore, Hitoshi Okamura, Jean-Michel Fustin, Yao Xu, Ellen Grünewald, Samantha J. Cargill, Shiqi Ye, Marijke Versteven

Publikováno v: Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-1 (2020)

The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating all aspects of cellular physiology. We have previously shown that methyl cycle inhibition in mammals strongly affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd78e5806f63516c23edcdd4fd0a392
http://europepmc.org/articles/PMC7272646

Researching the Self: Interdisciplinary Perspectives

Autor: Willem E. Frankenhuis, Editor, Ellen Grünewald, Editor

Researching the Self originated in a conference held at the University of Amsterdam in 2005, where scholars from various academic backgrounds presented their current theories and research. One central theme that emerged from the conference is the nee

DISC1 regulates N-Methyl-D-Aspartate receptor dynamics: Abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

Autor: David J. Porteous, Mostafa Kabiri, Hazel Davidson-Smith, David Price, Marion Bonneau, Daniel L. McCartney, Miles D. Houslay, Paul Perry, J. Kirsty Millar, Kyriakos D. Economides, Shaun Mackie, Laura C. Murphy, Michel Didier, Fumiaki Ogawa, H. Greg Polites, Stephen M. Lawrie, Ellen Grünewald, Barbara Duff, Kathryn L. Evans, Colin A. Semple, Shane T. O’Sullivan, Darragh K. Crummie, Mandy Johnstone, Helen S. Torrance, Jonathan Phillips, Andrew M. McIntosh, Elise L.V. Malavasi, Philippe Gautier, Karen Burr, Costas Constantinides, Susan Anderson, Paraskevi Makedonopoulou, Siddharthan Chandran, Douglas Blackwood, Hannah Murdoch, Matthew Pearson

Publikováno v: Malavasi, E L V, Economides, K D, Grünewald, E, Makedonopoulou, P, Gautier, P, Mackie, S, Murphy, L C, Murdoch, H, Crummie, D, Ogawa, F, McCartney, D L, O'Sullivan, S T, Burr, K, Torrance, H S, Phillips, J, Bonneau, M, Anderson, S M, Perry, P, Pearson, M, Constantinides, C, Davidson-Smith, H, Kabiri, M, Duff, B, Johnstone, M, Polites, H G, Lawrie, S M, Blackwood, D H, Semple, C A, Evans, K L, Didier, M, Chandran, S, McIntosh, A M, Price, D J, Houslay, M D, Porteous, D J & Millar, J K 2018, ' DISC1 regulates N-methyl-D-aspartate receptor dynamics : abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness ', Translational Psychiatry, vol. 8, no. 1, 184 . https://doi.org/10.1038/s41398-018-0228-1
Malavasi, E L V, Economides, K D, Grünewald, E, Makedonopoulou, P, Gautier, P, Mackie, S, Murphy, L C, Murdoch, H, Crummie, D, Ogawa, F, McCartney, D L, O’Sullivan, S T, Burr, K, Torrance, H S, Phillips, J, Bonneau, M, Anderson, S M, Perry, P, Pearson, M, Constantinides, C, Davidson-Smith, H, Kabiri, M, Duff, B, Johnstone, M, Polites, H G, Lawrie, S M, Blackwood, D H, Semple, C A, Evans, K L, Didier, M, Chandran, S, McIntosh, A M, Price, D J, Houslay, M D, Porteous, D J & Millar, J K 2018, ' DISC1 regulates N-methyl-D-aspartate receptor dynamics : abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness ', Translational psychiatry, vol. 8, no. 1, 184 . https://doi.org/10.1038/s41398-018-0228-1
Translational Psychiatry
Translational Psychiatry, Vol 8, Iss 1, Pp 1-16 (2018)

The neuromodulatory gene DISC1 is disrupted by a t(1;11) translocation that is highly penetrant for schizophrenia and affective disorders, but how this translocation affects DISC1 function is incompletely understood. N-Methyl-D-Aspartate receptors (N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870cbede3d419f12ab6663ee499dc410

GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth

Autor: Ellen Grünewald, David J. Porteous, Pippa A. Thomson, Hazel L. Kinnell

Publikováno v: Molecular and Cellular Neuroscience. 42:363-371

G protein-coupled receptors (GPCRs) form a link between the cell and their environment when signalling pathways are activated upon ligand binding. However, the ligands and functions for many GPCRs remain to be determined. We sought to understand the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41da957dace6aba649e36e6a377c1b7f
https://doi.org/10.1016/j.mcn.2009.08.007