Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ellen G. Jarred"'
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Disrupted germline differentiation or compromised testis development can lead to subfertility or infertility and are strongly associated with testis cancer in humans. In mice, SRY and SOX9 induce expression of Fgf9, which promotes
Externí odkaz:
https://doaj.org/article/5fdde4b6e29544ef84dcfbc95872e4a6
Publikováno v:
F1000Research, Vol 7 (2018)
Epigenetic modifications, including DNA methylation and histone modifications, determine the way DNA is packaged within the nucleus and regulate cell-specific gene expression. The heritability of these modifications provides a memory of cell identity
Externí odkaz:
https://doaj.org/article/d2b3adbc33fa411f8e54b3a65860d9b4
Autor:
Lexie Prokopuk, Ellen G Jarred, Rheannon O Blücher, Eileen A McLaughlin, Jessica M Stringer, Patrick S Western
Publikováno v:
Reproduction. 163:167-182
Polycomb repressive complex 2 (PRC2) catalyses the repressive epigenetic modification of histone 3 lysine 27 tri-methylation (H3K27me3) and functions as a key epigenetic regulator during embryonic development. PRC2 is known to regulate the developmen
Germline development provides the founding cells for spermatogenesis and oogenesis in males and females, respectively. Disrupted germline differentiation or compromised testis development can lead to subfertility or infertility and are strongly assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd67b5480a915420c48ac5b112b7ec2
https://doi.org/10.1101/2023.02.05.527224
https://doi.org/10.1101/2023.02.05.527224
Autor:
Ruby Oberin, Sigrid Petautschnig, Tesha Tsai, Ellen G. Jarred, Zhipeng Qu, Neil A. Youngson, Heidi Bildsoe, Thi T. Truong, Dilini Fernando, Maarten van den Buuse, David K. Gardner, Natalie A. Sims, David L. Adelson, Patrick S. Western
Germline epigenetic programming, including genomic imprinting, substantially influences offspring development. Polycomb Repressive Complex 2 (PRC2) plays an important role in Histone 3 Lysine 27 trimethylation (H3K27me3)-dependent imprinting, loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f57f80f631ac6487b003db5a4cb55a6
https://doi.org/10.1101/2022.08.08.503175
https://doi.org/10.1101/2022.08.08.503175
Autor:
Ellen G. Jarred, Zhipeng Qu, Tesha Tsai, Ruby Oberin, Sigrid Petautschnig, Heidi Bildsoe, Stephen Pederson, Qing-hua Zhang, Jessica M. Stringer, John Carroll, David K. Gardner, Maarten van den Buuse, Natalie A. Sims, William T. Gibson, David L. Adelson, Patrick S. Western
Publikováno v:
Clinical epigenetics. 14(1)
Background Non-genetic disease inheritance and offspring phenotype are substantially influenced by germline epigenetic programming, including genomic imprinting. Loss of Polycomb Repressive Complex 2 (PRC2) function in oocytes causes non-genetically
Publikováno v:
F1000Research
Epigenetic modifications, including DNA methylation and histone modifications, determine the way DNA is packaged within the nucleus and regulate cell-specific gene expression. The heritability of these modifications provides a memory of cell identity
Autor:
Ruby Oberin, Sigrid Petautschnig, Ellen G Jarred, Zhipeng Qu, Tesha Tsai, Neil A Youngson, Gabrielle Pulsoni, Thi T Truong, Dilini Fernando, Heidi Bildsoe, Rheannon O Blücher, Maarten van den Buuse, David K Gardner, Natalie A Sims, David L Adelson, Patrick S Western
Publikováno v:
eLife, Vol 13 (2024)
Germline epigenetic programming, including genomic imprinting, substantially influences offspring development. Polycomb Repressive Complex 2 (PRC2) plays an important role in Histone 3 Lysine 27 trimethylation (H3K27me3)-dependent imprinting, loss of
Externí odkaz:
https://doaj.org/article/76f117b6b7a24bfc9e0a47cd99baddff