Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ellen F. Young"'
Autor:
Deanna R. Zhu, Alecia J. Rajesh, Rita M. Meganck, Ellen F. Young, Jennifer E. Munt, Victor L. Tse, Boyd Yount, Helen Conrad, Laura White, Sandra Henein, Aravinda M. DeSilva, Ralph S. Baric
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The DENV envelope (E) and pre-membrane (prM) glycoproteins are primary targets of serologic immunity after infection and vaccination. Of these, serotype-specific (TS) antibodies typically target E domains, while serotype cross-reactive (CR)
Externí odkaz:
https://doaj.org/article/eab47b3ba62a4f2eaf820d656fe74080
Autor:
Emily N. Gallichotte, Ellen F. Young, Thomas J. Baric, Boyd L. Yount, Stefan W. Metz, Matthew C. Begley, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Zika virus (ZIKV) is a flavivirus that is structurally highly similar to the related viruses, dengue virus (DENV), West Nile virus, and yellow fever virus. ZIKV causes an acute infection that often results in mild symptoms but that can cause
Externí odkaz:
https://doaj.org/article/f659dd33a20641e28415e64c39b45e5e
Autor:
Stephanie A Montgomery, Ellen F Young, Phillip G Durham, Katelyn E Zulauf, Laura Rank, Brittany K Miller, Jennifer D Hayden, Feng-Chang Lin, John T Welch, Anthony J Hickey, Miriam Braunstein
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases j
Externí odkaz:
https://doaj.org/article/54319f93be4845eab70a517b83e13e36
Autor:
Ellen F. Young, Phillip G. Durham, Ellen F. Perkowski, Seidu Malik, Anthony J. Hickey, Miriam Braunstein
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 135
Autor:
Nancy Cheng, Melissa A Porter, Lloyd W Frick, Yvonne Nguyen, Jennifer D Hayden, Ellen F Young, Miriam S Braunstein, Emily A Hull-Ryde, William P Janzen
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96348 (2014)
The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat
Externí odkaz:
https://doaj.org/article/d10bfff817c7471aaf6c76ab85f5218f
Autor:
Elizabeth C. Adams, Aravinda M. de Silva, Ellen F. Young, Laura J. White, Ralph S. Baric, Sandra Henein, Mark Stoops
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009258 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe d
Autor:
Snm Hanif, Phillip G. Durham, Miriam Braunstein, Ellen F. Young, Anthony J. Hickey, Lucia Garcia Contreras
Publikováno v:
Journal of Visualized Experiments.
Development of new therapeutic products requires efficacy testing in an animal model. The pulmonary route of administration can be utilized to deliver drugs locally and systemically. Evaluation of dry powder aerosols necessitates an efficient dispers
Autor:
Benjamin G. Vincent, Edward J. Collins, Ellen F. Young, Paul R. Hess, Keith R. Miller, Sabrina M. Hess, Adam Buntzman, Jeffrey A. Frelinger
Publikováno v:
Transplant Immunology. 29:138-145
Alloreactive T-cell responses directed against minor histocompatibility (H) antigens, which arise from diverse genetic disparities between donor and recipient outside the MHC, are an important cause of rejection of MHC-matched grafts. Because clinica
Autor:
Anthony J. Hickey, Stephanie A. Montgomery, Phillip Durham, Ellen F. Young, Miriam Braunstein, Katelyn E. Zulauf, Jennifer D. Hayden, Feng-Chang Lin, Laura Rank, John T. Welch, Brittany K. Miller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases j
Autor:
Adam Buntzman, Greg S. Gojanovich, Ellen F. Young, Benjamin G. Vincent, Sabrina L. Murray, Paul R. Hess
Publikováno v:
Journal of diabetes science and technology. 6(3)
Major histocompatibility complex (MHC) class I and MHC class II molecules present short peptides that are derived from endogenous and exogenous proteins, respectively, to cognate T-cell receptors (TCRs) on the surface of T cells. The exquisite specif