Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ellen F. Fynan"'
Publikováno v:
Human Gene Therapy
DNA vaccines were pioneered by several groups in the early 1990s. This article presents the reflections of one of these groups on their work with retroviral vectors in chickens that contributed to the discovery and early development of DNA vaccines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bad858eaf22facceacf28c01dc193d
https://doi.org/10.1089/hum.2018.066
https://doi.org/10.1089/hum.2018.066
Autor:
Harry B. Greenberg, Ellen F. Fynan, Graham Henry Farrar, David Hugh Jones, Shing C. Chen, John E. Herrmann, Anne Margaret Tinsley-Bown
Publikováno v:
Virology. 259:148-153
Protective immune responses in mice were obtained after oral immunization with rotavirus DNA vaccines encapsulated in poly(lactide-co-glycolide) (PLG) microparticles. The DNA vaccines used encoded outer capsid proteins VP4 and VP7; proteins that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30a58547e0f6a5be50af4074c1d279c
https://doi.org/10.1006/viro.1999.9751
https://doi.org/10.1006/viro.1999.9751
Autor:
Robert G. Webster, Ellen F. Fynan, Deborah H. Fuller, Harriet L. Robinson, Joseph C. Santoro, Joel R. Haynes
Publikováno v:
International Journal of Immunopharmacology. 17:79-83
Direct DNA inoculations are being developed as a method of subunit vaccination. Plasmid DNAs encoding influenza virus hemagglutinin glycoproteins have been tested for the ability to provide protection against lethal influenza challenges. In immunizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab0d8c86893e454f185b5c2cde3940e
https://doi.org/10.1016/0192-0561(94)00090-b
https://doi.org/10.1016/0192-0561(94)00090-b
Publikováno v:
DNA and Cell Biology. 12:785-789
Recently, we demonstrated that direct inoculation of a hemagglutinin 7 (H7)-expressing DNA could vaccinate chickens against a lethal H7 influenza virus challenge. These experiments used a defective-retroviral-based vector to express H7 (p188) (Robins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642e8c2005e4eaf3ed212082ba538c0f
https://doi.org/10.1089/dna.1993.12.785
https://doi.org/10.1089/dna.1993.12.785
Publikováno v:
Journal of General Virology. 74:2163-2170
The physical and biological state of the Marek's disease virus (MDV) genome in avian leukosis virus (ALV)-transformed cells is characterized using cell lines established from ALV tumours co-infected with the SB-1 strain of MDV. The MDV genome within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b4bd829cebd5c069342fe156fd805f
https://doi.org/10.1099/0022-1317-74-10-2163
https://doi.org/10.1099/0022-1317-74-10-2163
Publikováno v:
Vaccine. 17(23-24)
We have previously shown that gene-gun delivery of murine rotavirus DNA vaccines to the epidermis induced protection against rotavirus challenge in mice. In this study, we used a rotavirus group antigen (VP6)-specific DNA vaccine to compare epidermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e214eeebc068365f6d1c68d685e1a63a
https://pubmed.ncbi.nlm.nih.gov/10462253
https://pubmed.ncbi.nlm.nih.gov/10462253
Autor:
Harry B. Greenberg, David Hugh Jones, J. Christopher S. Clegg, John E. Herrmann, Graham Henry Farrar, Ellen F. Fynan, Shing C. Chen
DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-coated particles into the epidermis. Induction of mucosal immunity by targeting DNA vaccines to mucosal surfaces may offer advantages, and an oral vaccine could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5374bc91bd4b971c26f1a75dfef69879
https://europepmc.org/articles/PMC110376/
https://europepmc.org/articles/PMC110376/
Autor:
Harriet L. Robinson, Harry B. Greenberg, Shan Lu, John E. Herrmann, Ellen F. Fynan, Shing C. Chen, Joseph C. Santoro
Publikováno v:
Vaccine. 15(8)
It is estimated that Group A rotavirus diarrhea causes as many as one million deaths per year in children worldwide, and effective vaccines will be essential for their control. Plasmid DNA vaccines encoding murine rotaviral proteins VP4, VP6, or VP7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2192f3f0d49677c74f7cd41b3423346e
https://pubmed.ncbi.nlm.nih.gov/9234543
https://pubmed.ncbi.nlm.nih.gov/9234543
Autor:
Harriet L. Robinson, Harry B. Greenberg, Shixia Wang, Ellen F. Fynan, Shing C. Chen, Joseph C. Santoro, John E. Herrmann
Publikováno v:
The Journal of infectious diseases. 174
DNA vaccines encoding for murine rotavirus proteins VP4, VP6, or VP7 were tested in adult BALB/c mice for their ability to induce immune responses and protect against rotavirus challenge. A gene gun was used to inoculate vaccines into the epidermis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0a2cbf9c00fbcf15f58082c4d2cb82
https://pubmed.ncbi.nlm.nih.gov/8752297
https://pubmed.ncbi.nlm.nih.gov/8752297
Publikováno v:
Vaccine. 12(16)
Immunization of ferrets with a plasmid DNA expressing influenza virus haemagglutinin (pCMV/H1 DNA) provided complete protection from challenge with the homologous A/PR/8/34 (HINI) influenza virus. Delivery of DNA-coated gold beads by gene gun to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d86e0b1295ee563f2039029d5cf0857
https://pubmed.ncbi.nlm.nih.gov/7879412
https://pubmed.ncbi.nlm.nih.gov/7879412