Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ellen F Young"'
Autor:
Laura J White, Ellen F Young, Mark J Stoops, Sandra R Henein, Elizabeth C Adams, Ralph S Baric, Aravinda M de Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009258 (2021)
The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe d
Externí odkaz:
https://doaj.org/article/3bc10f712c7a48a7b7795425067dcfd9
Autor:
Stephanie A Montgomery, Ellen F Young, Phillip G Durham, Katelyn E Zulauf, Laura Rank, Brittany K Miller, Jennifer D Hayden, Feng-Chang Lin, John T Welch, Anthony J Hickey, Miriam Braunstein
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases j
Externí odkaz:
https://doaj.org/article/54319f93be4845eab70a517b83e13e36
Autor:
Nancy Cheng, Melissa A Porter, Lloyd W Frick, Yvonne Nguyen, Jennifer D Hayden, Ellen F Young, Miriam S Braunstein, Emily A Hull-Ryde, William P Janzen
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96348 (2014)
The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat
Externí odkaz:
https://doaj.org/article/d10bfff817c7471aaf6c76ab85f5218f
Autor:
Deanna R. Zhu, Alecia J. Rajesh, Rita M. Meganck, Ellen F. Young, Jennifer E. Munt, Victor L. Tse, Boyd Yount, Helen Conrad, Laura White, Sandra Henein, Aravinda M. DeSilva, Ralph S. Baric
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The DENV envelope (E) and pre-membrane (prM) glycoproteins are primary targets of serologic immunity after infection and vaccination. Of these, serotype-specific (TS) antibodies typically target E domains, while serotype cross-reactive (CR)
Externí odkaz:
https://doaj.org/article/eab47b3ba62a4f2eaf820d656fe74080
Autor:
Emily N. Gallichotte, Stefan W. Metz, Boyd Yount, Ralph S. Baric, Matthew Begley, Ellen F. Young, Thomas J. Baric, Aravinda M. de Silva
Publikováno v:
mBio
mBio, Vol 10, Iss 5, p e01485-19 (2019)
mBio, Vol 10, Iss 5 (2019)
mBio, Vol 10, Iss 5, p e01485-19 (2019)
mBio, Vol 10, Iss 5 (2019)
Zika virus is a flavivirus that was recently introduced to Latin America, where it caused a massive epidemic. Individuals infected with ZIKV generate an immune response composed of antibodies which bind to the envelope (E) protein. These anti-E antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d2a0a0b4b5e093958d426a0d86a6ce
http://europepmc.org/articles/PMC6751055
http://europepmc.org/articles/PMC6751055
Autor:
Elizabeth C. Adams, Aravinda M. de Silva, Ellen F. Young, Laura J. White, Ralph S. Baric, Sandra Henein, Mark Stoops
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009258 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec32e29e0b1e6497a9ddb341913c0d00
https://doi.org/10.1371/journal.pntd.0009258
https://doi.org/10.1371/journal.pntd.0009258
Autor:
Snm Hanif, Phillip G. Durham, Miriam Braunstein, Ellen F. Young, Anthony J. Hickey, Lucia Garcia Contreras
Publikováno v:
Journal of Visualized Experiments.
Development of new therapeutic products requires efficacy testing in an animal model. The pulmonary route of administration can be utilized to deliver drugs locally and systemically. Evaluation of dry powder aerosols necessitates an efficient dispers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449576304edc0559aaea2fb593b91a5f
https://doi.org/10.3791/55356-v
https://doi.org/10.3791/55356-v
Autor:
Benjamin G. Vincent, Edward J. Collins, Ellen F. Young, Paul R. Hess, Keith R. Miller, Sabrina M. Hess, Adam Buntzman, Jeffrey A. Frelinger
Publikováno v:
Transplant Immunology. 29:138-145
Alloreactive T-cell responses directed against minor histocompatibility (H) antigens, which arise from diverse genetic disparities between donor and recipient outside the MHC, are an important cause of rejection of MHC-matched grafts. Because clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1feb6fe3adaba9980fa537ef1a2865c3
https://doi.org/10.1016/j.trim.2013.10.005
https://doi.org/10.1016/j.trim.2013.10.005
Autor:
Anthony J. Hickey, Stephanie A. Montgomery, Phillip Durham, Ellen F. Young, Miriam Braunstein, Katelyn E. Zulauf, Jennifer D. Hayden, Feng-Chang Lin, Laura Rank, John T. Welch, Brittany K. Miller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
PLoS ONE, Vol 13, Iss 9, p e0204495 (2018)
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1299cc4a97e46a81242122a05a024e65
https://doi.org/10.1371/journal.pone.0204495
https://doi.org/10.1371/journal.pone.0204495
Autor:
Adam Buntzman, Greg S. Gojanovich, Ellen F. Young, Benjamin G. Vincent, Sabrina L. Murray, Paul R. Hess
Publikováno v:
Journal of diabetes science and technology. 6(3)
Major histocompatibility complex (MHC) class I and MHC class II molecules present short peptides that are derived from endogenous and exogenous proteins, respectively, to cognate T-cell receptors (TCRs) on the surface of T cells. The exquisite specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b4dd70eeecbd8c4d808fb3bfa3f4ca
https://pubmed.ncbi.nlm.nih.gov/22768881
https://pubmed.ncbi.nlm.nih.gov/22768881