Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.

Autor: Ikonomov OC; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA., Sbrissa D; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA., Venkatareddy M; Division of Nephrology, University of Michigan, Ann Arbor, MI 48109, USA., Tisdale E; Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA., Garg P; Division of Nephrology, University of Michigan, Ann Arbor, MI 48109, USA., Shisheva A; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA. Electronic address: ashishev@med.wayne.edu.

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2015 May; Vol. 1853 (5), pp. 1240-50. Date of Electronic Publication: 2015 Jan 22.