Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Ellen E. Ladenheim"'
Autor:
Jason Kirkness, David D. Fuller, Qiaoling Yao, Ellen E. Ladenheim, Alan R. Schwartz, Sheng Bi, Huy Pho, Vsevolod Y. Polotsky, Timothy H. Moran
Publikováno v:
Sleep. 39:1097-1106
Study objectives Obesity hypoventilation and obstructive sleep apnea are common complications of obesity linked to defects in respiratory pump and upper airway neural control. Leptin-deficient ob/ob mice have impaired ventilatory control and inspirat
Autor:
Kenneth W. Fishbein, Huy Pho, Luiz Ubirajara Sennes, Richard G. Spencer, Luu V. Pham, Olga Dergacheva, Thomaz Fleury Curado, Michael J Brennick, Alan R. Schwartz, Vsevolod Y. Polotsky, David Mendelowitz, Ellen E. Ladenheim
Publikováno v:
Scientific Reports
Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx.
Autor:
Harry R. Kissileff, Ellen E. Ladenheim
Publikováno v:
Physiology & Behavior. 121:3-9
This review summarizes the formation of the Society for the Study of Ingestive Behavior (SSIB), highlighting the many people whose commitment and perseverance brought together a wide range of disciplines for the common goal of investigating ingestive
Autor:
Timothy H. Moran, Ellen E. Ladenheim
Publikováno v:
Gastroenterology clinics of North America. 45(4)
Multiple physiologic and neural systems contribute to the controls over what and how much we eat. These systems include signaling involved in the detection and signaling of nutrient availability, signals arising from consumed nutrients that provide f
Autor:
Ellen E. Ladenheim, Kellie L.K. Tamashiro, Xueping Li, Nicholas T. Bello, Timothy H. Moran, Susan Aja, Christopher A. Ross, Sheng Bi, Wanli W. Smith, Xiaofang Wang, Zhaohui Liu
Publikováno v:
International journal of obesity (2005)
Aims The pathogenesis of obesity remains incompletely understood and the exploration of the role of novel proteins in obesity may provide important insights into its causes and treatments. Here we report a previously unidentified role for synphilin-1
Autor:
Ellen E. Ladenheim, Timothy H. Moran
Publikováno v:
Physiology & Behavior. 103:21-24
Signaling from energy stores provides feedback on overall nutrient availability to influence food intake. Beginning with seminal studies by Woods and colleagues identifying insulin as an adiposity signal, it has become clear that such factors affect
Publikováno v:
Endocrinology. 150:672-678
Gastrin-releasing peptide (GRP) is a bombesin-like peptide widely distributed in the gastrointestinal tract and central nervous system. In the brain, GRP mRNA is located in the hypothalamic paraventricular nucleus (PVN), a region that receives neural
Autor:
Wendy Keung, Timothy H. Moran, Ken Strynadka, Ellen E. Ladenheim, Yajun Tu, Kellie L.K. Tamashiro, Shigeru Chohnan, Morris J. Birnbaum, Gabriele V. Ronnett, Susan Aja, Kimberly P. Kinzig, Su Gao, Gary D. Lopaschuk, Karen A. Scott, Sandra E. Kelly, Wanli W. Smith
Publikováno v:
Proceedings of the National Academy of Sciences. 104:17358-17363
Hypothalamic fatty acid metabolism has recently been implicated in the controls of food intake and energy homeostasis. We report that intracerebroventricular (ICV) injection of leptin, concomitant with inhibiting AMP-activated kinase (AMPK), activate
Publikováno v:
Physiology & Behavior. 89:511-516
Leptin reduces food intake through a specific effect on meal size. Investigations into how this within meal effect of leptin is mediated have demonstrated that leptin increases the ability of within meal inhibitory feedback signaling to limit intake
Autor:
Kimberly P. Kinzig, Ulrika Smedh, Ellen E. Ladenheim, Susan Knipp, Karen A. Scott, Timothy H. Moran
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 288:R384-R388
Peptide YY3–36 [PYY(3–36)], a gastrointestinal peptide that is released into the circulation in response to ingesting a meal, has recently been suggested to play a role in controlling food intake. PYY(3–36) has been reported to inhibit food int