Molecular Mechanism for the Interactions of Hofmeister Cations with Macromolecules in Aqueous Solution

Autor: Chad I. Drexler, Halil I. Okur, Paul S. Cremer, Ellen E Bruce, Bradley A. Rogers, Nico F. A. van der Vegt, Sina Stegmaier, Sylvie Roke

Publikováno v: Journal of the American Chemical Society

Ion identity and concentration influence the solubility of macromolecules. To date, substantial effort has been focused on obtaining a molecular level understanding of specific effects for anions. By contrast, the role of cations has received signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600516a85f8e2a19a6c04248d55bdca3
https://doi.org/10.1021/jacs.0c07214

Contact Ion Pairs in the Bulk Affect Anion Interactions with Poly(

Autor: Ellen E, Bruce, Pho T, Bui, Mengrui, Cao, Paul S, Cremer, Nico F A, van der Vegt

Publikováno v: The journal of physical chemistry. B. 125(2)

Salt effects on the solubility of uncharged polymers in aqueous solutions are usually dominated by anions, while the role of the cation with which they are paired is often ignored. In this study, we examine the influence of three aqueous metal iodide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::497c0e70c85649ff5a9b4688198142ef
https://pubmed.ncbi.nlm.nih.gov/33406822

Addition to 'Nonadditive Ion Effects Drive Both Collapse and Swelling of Thermoresponsive Polymers in Water'

Autor: Pho T. Bui, Nico F. A. van der Vegt, Bradley A. Rogers, Paul S. Cremer, Ellen E Bruce

Publikováno v: Journal of the American Chemical Society. 143:2456-2456

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69f827248d0ad9280a6c733857076236
https://doi.org/10.1021/jacs.1c00210

Clinical trial eligibility of a real-world connective tissue disease cohort: Results from the LEAP cohort.

Autor: Dyball S; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK. Electronic address: Sarah.dyball@manchester.ac.uk., Madenidou AV; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Rodziewicz M; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Reynolds JA; Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Rheumatology Department, Sandwell and West Birmingham NHS Trust, Birmingham, UK., Herrick AL; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK; Department of Rheumatology, Salford Care Organisation, Northern Care Alliance NHS Foundation Trust, Salford, UK., Haque S; Department of Rheumatology, Manchester University Foundation Trust, Wythenshawe Hospital, Manchester, UK., Chinoy H; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK; Department of Rheumatology, Salford Care Organisation, Northern Care Alliance NHS Foundation Trust, Salford, UK., Bruce E; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Bruce IN; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK., Parker B; The Kellgren Centre for Rheumatology, Manchester University Hospitals NHS Foundation Trust, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK.

Publikováno v: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2024 Aug; Vol. 67, pp. 152463. Date of Electronic Publication: 2024 May 22.

Translating research into clinical practice: quality improvement to halve non-adherence to methotrexate.

Autor: Barton A; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.; Versus Arthritis Centre for Genetics and Genomics, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Jani M; Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Bundy C; College of Biomedical and Life Sciences, School of Healthcare Sciences, Cardiff University, Cardiff.; Division of Musculoskeletal and Dermatological Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Bluett J; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.; Versus Arthritis Centre for Genetics and Genomics, Manchester Academic Health Science Centre, The University of Manchester, Manchester., McDonald S; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., Keevil B; Department of Clinical Biochemistry, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Dastagir F; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., Aris M; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., Bruce I; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.; Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Ho P; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., McCarthy E; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., Bruce E; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester., Parker B; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.; Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Hyrich K; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.; Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester., Gorodkin R; Kellgren Centre for Rheumatology, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Jan 05; Vol. 60 (1), pp. 125-131.