Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ellen C. Moore"'
Autor:
Jay Friedman, Megan Morisada, Lillian Sun, Ellen C. Moore, Michelle Padget, James W. Hodge, Jeffrey Schlom, Sofia R. Gameiro, Clint T. Allen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Natural killer (NK) cells recognize and lyse target tumor cells in an MHC-unrestricted fashion and complement antigen- and MHC-restricted killing by T-lymphocytes. NK cells and T-lymphocytes mediate early killing of targets throug
Externí odkaz:
https://doaj.org/article/9452867cafaa4abaadb8103de56db9b3
Autor:
Ellen C. Moore, Lillian Sun, Paul E. Clavijo, Jay Friedman, Joe B. Harford, Anthony D. Saleh, Carter Van Waes, Esther H. Chang, Clint T. Allen
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
Loss or mutation of TP53 has been linked to alterations in anti-tumor immunity as well as dysregulation of cell cycle and apoptosis. We explored immunologic effects and mechanisms following restoration of wild-type human TP53 cDNA in murine oral canc
Externí odkaz:
https://doaj.org/article/0597348176a347c2bbfba1afd61182b4
Autor:
Clint T. Allen, Elizabeth E. Evans, Maurice Zauderer, Ernest Smith, Ellen C. Moore, Yvette Robbins, Jay Friedman, Paul E. Clavijo
Demonstrates peripheral MDSC changes, tumor effector immune cell changes and ex vivo T-cell functional data important to a thorough understanding of how Sema4D blockade alters tumor immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5badea67c47b5c27378442d53dcf9f
https://doi.org/10.1158/2326-6066.22539299
https://doi.org/10.1158/2326-6066.22539299
Autor:
Clint T. Allen, Carter Van Waes, James W. Hodge, Ravindra Uppaluri, Andria M. Caruso, Harrison A. Cash, Ellen C. Moore
This file contains detailed methods for both our in vivo animal and flow cytometry experiments. This includes drug doses and scheduling, an inventory of antibodies, and appropriate supporting references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7233fe1a437e3c7d8ed9c70542604c6e
https://doi.org/10.1158/2326-6066.22537364.v1
https://doi.org/10.1158/2326-6066.22537364.v1
Autor:
Clint T. Allen, Carter Van Waes, James W. Hodge, Ravindra Uppaluri, Andria M. Caruso, Harrison A. Cash, Ellen C. Moore
Contains supplemental figures 1 through 4 and their corresponding legends. Suppl Fig 1 demonstrates summary growth curves for in vivo MOC1 and MOC2 experiments. Suppl Fig 2 is validation of p15E antigen expression in MOC cell lines. Supple Fig 3 demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c14a08badb9d9de55d41eb94551f975
https://doi.org/10.1158/2326-6066.22537361.v1
https://doi.org/10.1158/2326-6066.22537361.v1
Autor:
Clint T. Allen, Carter Van Waes, James W. Hodge, Ravindra Uppaluri, Andria M. Caruso, Harrison A. Cash, Ellen C. Moore
Significant subsets of patients with oral cancer fail to respond to single-agent programmed death (PD) blockade. Syngeneic models of oral cancer were used to determine if blocking oncogenic signaling improved in vivo responses to PD-L1 monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc971743fb536ba9999cb53b08ce81e
https://doi.org/10.1158/2326-6066.c.6548414.v1
https://doi.org/10.1158/2326-6066.c.6548414.v1
Autor:
Clint T. Allen, Elizabeth E. Evans, Maurice Zauderer, Ernest Smith, Ellen C. Moore, Yvette Robbins, Jay Friedman, Paul E. Clavijo
Tumor infiltration by immunosuppressive myeloid cells, such as myeloid-derived suppressor cells (MDSCs), causes resistance to immunotherapy. Semaphorin4D, originally characterized for its axonal guidance properties, also contributes to endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::458388c807fc35990be5c43bdeb12d22
https://doi.org/10.1158/2326-6066.c.6549047.v1
https://doi.org/10.1158/2326-6066.c.6549047.v1
Autor:
Clint Allen, Ravindra Uppaluri, Carter Van Waes, Hans Schreiber, James W. Hodge, Nicole Schmitt, Wojciech K. Mydlarz, Megan V. Morisada, Sarah Greene, Lilian Sun, Paul E. Clavijo, Yvette Robbins, Paul Zolkind, Ellen C. Moore, Jay Friedman
Supplemental data not critical for the main conclusions of the work but important for critical review of the data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8edadb7c9d403686753efd5bac3db1
https://doi.org/10.1158/1078-0432.22477623
https://doi.org/10.1158/1078-0432.22477623
Autor:
Clint Allen, Carter Van Waes, Chris Silvin, Zhong Chen, Harrison Cash, Jay Friedman, Paul E. Clavijo, Ellen C. Moore, Ruth J. Davis
The supplemental figures demonstrate data supportive of the overall conclusions of this manuscript including MDSC flow cytometry gating strategy, evidence for moderate suppression of peripheral MDSC T-lymphocyte suppressive capacity after IPI-145 mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be2d62a9996ce9a40d930f82060185e
https://doi.org/10.1158/0008-5472.22413357.v1
https://doi.org/10.1158/0008-5472.22413357.v1
Autor:
Clint Allen, Ravindra Uppaluri, Carter Van Waes, Hans Schreiber, James W. Hodge, Nicole Schmitt, Wojciech K. Mydlarz, Megan V. Morisada, Sarah Greene, Lilian Sun, Paul E. Clavijo, Yvette Robbins, Paul Zolkind, Ellen C. Moore, Jay Friedman
Purpose:Surgical resection of primary tumor with regional lymphadenectomy remains the treatment of choice for patients with advanced human papillomavirus–negative head and neck squamous cell carcinoma. However, even when pathologic disease-free mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de81563eb2f456c738cee6f8856993c
https://doi.org/10.1158/1078-0432.c.6529710.v1
https://doi.org/10.1158/1078-0432.c.6529710.v1