Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ellen Bushell"'
Autor:
Edward J. Marr, Burcu Anar, David A. Baker, Ellen Bushell, Jason P. Mooney, Philip J Spence, Oliver Billker, Wiebke Nahrendorf, Joanne Thompson, Rachel M Milne, Julian C. Rayner, Frank Schwach, Deirdre Cunningham, Jean Langhorne, Gareth Girling
Publikováno v:
Marr, E J, Milne, R M, Anar, B, Girling, G, Schwach, F, Mooney, J P, Nahrendorf, W, Spence, P J, Cunningham, D, Baker, D A, Langhorne, J, Rayner, J C, Billker, O, Bushell, E S & Thompson, J 2020, ' An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi ', Wellcome Open Research, vol. 5, pp. 71 . https://doi.org/10.12688/wellcomeopenres.15587.2
Wellcome Open Research
Wellcome Open Research
The rodent parasite Plasmodium chabaudi is an important in vivo model of malaria. The ability to produce chronic infections makes it particularly useful for investigating the development of anti-Plasmodium immunity, as well as features associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622139050da721c4c8ce307f2fa42d23
Autor:
Vassily Hatzimanikatis, Magali Roques, Chris J. Janse, Frank Schwach, Oliver Billker, Volker Heussler, Colin Herd, Theo Sanderson, Dominique Soldati-Favre, Julian C. Rayner, Tom Metcalf, Ellen Bushell, Murielle Golomingi, Anush Chiappino-Pepe, Blandine Franke-Fayard, Séverine Chevalley, Mary Nyonda, Rebecca R. Stanway, Vikash Pandey, Jai Ramesar, Paul-Christian Burda, Reto Caldelari
Publikováno v:
Cell
Stanway, Rebecca R.; Bushell, Ellen; Chiappino-Pepe, Anush; Roques, Magali; Sanderson, Theo; Franke-Fayard, Blandine; Caldelari, Reto; Golomingi, Murielle; Nyonda, Mary; Pandey, Vikash; Schwach, Frank; Chevalley, Séverine; Ramesar, Jai; Metcalf, Tom; Herd, Colin; Burda, Paul-Christian; Rayner, Julian C.; Soldati-Favre, Dominique; Janse, Chris J.; Hatzimanikatis, Vassily; ... (2019). Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage. Cell, 179(5), 1112-1128.e26. Cell Press 10.1016/j.cell.2019.10.030
Cell, Vol. 179, No 5 (2019) pp. 1112-1128.e26
Cell, 179(5), 1112-+. CELL PRESS
Stanway, Rebecca R.; Bushell, Ellen; Chiappino-Pepe, Anush; Roques, Magali; Sanderson, Theo; Franke-Fayard, Blandine; Caldelari, Reto; Golomingi, Murielle; Nyonda, Mary; Pandey, Vikash; Schwach, Frank; Chevalley, Séverine; Ramesar, Jai; Metcalf, Tom; Herd, Colin; Burda, Paul-Christian; Rayner, Julian C.; Soldati-Favre, Dominique; Janse, Chris J.; Hatzimanikatis, Vassily; ... (2019). Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage. Cell, 179(5), 1112-1128.e26. Cell Press 10.1016/j.cell.2019.10.030
Cell, Vol. 179, No 5 (2019) pp. 1112-1128.e26
Cell, 179(5), 1112-+. CELL PRESS
Summary Plasmodium gene functions in mosquito and liver stages remain poorly characterized due to limitations in the throughput of phenotyping at these stages. To fill this gap, we followed more than 1,300 barcoded P. berghei mutants through the life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93aa9db1f64c2b2142bfcfe32439094
https://pubmed.ncbi.nlm.nih.gov/31730853
https://pubmed.ncbi.nlm.nih.gov/31730853
Autor:
Burcu Anar, Theo Sanderson, Colin Herd, Julian C. Rayner, Jyoti S. Choudhary, Tom Metcalf, Oliver Billker, Lu Yu, Charles Hillier, Mercedes Pardo Calvo, Ellen Bushell
Publikováno v:
SSRN Electronic Journal.
Malaria represents a major global health issue, and the identification and prioritisation of new intervention targets remains an urgent priority. This search is significantly hampered by the fact that over a third of the genes of the malaria-causing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb7a135ff3a5c94c109a7645089045d
https://doi.org/10.2139/ssrn.3314563
https://doi.org/10.2139/ssrn.3314563
Autor:
Ellen Bushell, Photini Sinnis, Amanda E. Balaban, Julian C. Rayner, Oliver Billker, Christine S. Hopp
Publikováno v:
Cellular Microbiology. 18:1625-1641
As the Plasmodium parasite transitions between mammalian and mosquito host, it has to adjust quickly to new environments. Palmitoylation, a reversible and dynamic lipid post‐translational modificat ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a001329d5e945ebd422ab38813ac2a1f
https://doi.org/10.1111/cmi.12601
https://doi.org/10.1111/cmi.12601
Autor:
Chris I. Newbold, Samuel O. Oyola, Sylvain Gandon, Ana Rivero, Antoine Nicot, Matthew Berriman, Ellen Bushell, Thomas D. Otto, Oliver Billker, Sascha Steinbiss, James Cotton, Kailash P. Patra, Ulrike Böhme, Katarzyna Modrzynska, Mandy Sanders, Joseph M. Vinetz, Colin Herd
Publikováno v:
Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (4), pp.547-560. ⟨10.1101/gr.218123.116⟩
Genome Research, 2018, 28 (4), pp.547-560. ⟨10.1101/gr.218123.116⟩
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (4), pp.547-560. ⟨10.1101/gr.218123.116⟩
Genome Research, 2018, 28 (4), pp.547-560. ⟨10.1101/gr.218123.116⟩
Avian malaria parasites are prevalent around the world, and infect a wide diversity of bird species. Here we report the sequencing and analysis of high quality draft genome sequences for two avian malaria species, Plasmodium relictum and Plasmodium g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a868fd3371353e2f7f542ad428597167
https://ora.ox.ac.uk/objects/uuid:c8e17756-8df7-4311-99fa-926995233011
https://ora.ox.ac.uk/objects/uuid:c8e17756-8df7-4311-99fa-926995233011
Autor:
Mercedes Pardo, Colin Herd, Jyoti S. Choudhary, Julian C. Rayner, Lu Yu, Charles Hillier, Theo Sanderson, Oliver Billker, Ellen Bushell, Tom Metcalf, Burcu Anar
Publikováno v:
Cell Reports
Summary Malaria represents a major global health issue, and the identification of new intervention targets remains an urgent priority. This search is hampered by more than one-third of the genes of malaria-causing Plasmodium parasites being uncharact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34498230adf2ecbcd96e0afa19c91e43
https://doi.org/10.1016/j.celrep.2019.07.019
https://doi.org/10.1016/j.celrep.2019.07.019
Global Analysis of Apicomplexan Protein S‐Acyl Transferases Reveals an Enzyme Essential for Invasion
Autor:
Julian C. Rayner, Karine Frénal, Yonggen Jia, Oliver Billker, Christina Mueller, Dominique Soldati-Favre, Ellen Bushell, Chwen L. Tay, Arnault Graindorge
Publikováno v:
Traffic; Vol 14
Traffic (Copenhagen, Denmark)
Traffic, Vol. 14, No 8 (2013) pp. 895-911
Traffic
Traffic (Copenhagen, Denmark)
Traffic, Vol. 14, No 8 (2013) pp. 895-911
Traffic
The advent of techniques to study palmitoylation on a whole proteome scale has revealed that it is an important reversible modification that plays a role in regulating multiple biological processes. Palmitoylation can control the affinity of a protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a5754621c9f3a7a61058380e50fe34
https://doi.org/10.1111/tra.12081
https://doi.org/10.1111/tra.12081
Autor:
Chris I. Newbold, Tom Metcalf, Mandy Sanders, Philip J Spence, Oliver Billker, Thibaut Brugat, Sarah McLaughlin, Ellen Bushell, Irene Tumwine, Solomon Conteh, Jing-wen Lin, Ulrike Böhme, Matthew Berriman, Adam J. Reid, Deirdre Cunningham, Garikai Kushinga, Patrick E. Duffy, Jean Langhorne
Publikováno v:
Brugat, T, Reid, A J, Lin, J, Cunningham, D, Tumwine, I, Kushinga, G, McLaughlin, S, Spence, P, Böhme, U, Sanders, M, Conteh, S, Bushell, E, Metcalf, T, Billker, O, Duffy, P E, Newbold, C I, Berriman, M & Langhorne, J 2017, ' Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection ', Nature Microbiology, vol. 2, 16276 . https://doi.org/10.1038/nmicrobiol.2016.276
Malaria is caused by parasites of the genus Plasmodium. All human-infecting Plasmodium species can establish long-lasting chronic infections1-5, creating an infectious reservoir to sustain transmission1,6. It is widely accepted that maintenance of ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8199ad2a2c2b33b2d53c082ccb39e302
https://pubmed.ncbi.nlm.nih.gov/28349951
https://pubmed.ncbi.nlm.nih.gov/28349951
Autor:
Guochun Liao, Belinda Wang, Peter J. M. Openshaw, Gary Peltz, Dagmar Mihm, Ellen Bushell, John S. Tregoning, Yuko Yamaguchi, James A. Harker, Ming Zheng
Publikováno v:
The Journal of Immunology. 185:5384-5391
Respiratory syncytial virus (RSV) is a major cause of respiratory morbidity, resulting in hospitalization for bronchiolitis in some infected infants that is associated with wheeze in later life. Genetic factors are known to affect the severity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724e71bb7165897aa71476a8b86d0bc2
https://doi.org/10.4049/jimmunol.1001594
https://doi.org/10.4049/jimmunol.1001594
Publikováno v:
Molecular Microbiology. 70:209-220
Transmission from the vertebrate host to the mosquito vector represents a major population bottleneck in the malaria life cycle that can successfully be targeted by intervention strategies. However, to date only about 25 parasite proteins expressed d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19827ba96ad77ed7645c78ffe53ee4fa
https://doi.org/10.1111/j.1365-2958.2008.06407.x
https://doi.org/10.1111/j.1365-2958.2008.06407.x