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pro vyhledávání: '"Ellen Bealing"'
Supplementary Figures 1-8 from Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy
Autor:
Alison H. Banham, Adrian L. Harris, Penny A. Handford, Nicola R. Sibson, James Larkin, Manuel Sarmiento-Soto, Sébastien Serres, Devon Sheppard, Chandramouli Chillakuri, Ji-Liang Li, Ellen Bealing, Jenna Yates, Stephen Stribbling, Sarah Watts, Tasneem Hassanali, Jenny Greig, Carol Bentley, Pat Whiteman, Demin Li, Massimo Masiero
1: JAG1 antibody characterization. 2: antibody inhibition of JAG1 mediated Notch signalling in tumor cell lines. 3: antibody inhibition of JAG1 signalling in vascular cells. 4: antibody inhibition of JAG1 signalling in HUVEC-HUVSMC co-culture. 5: eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d318461372ffb99d014884e8a0f6cac2
https://doi.org/10.1158/1535-7163.22510647
https://doi.org/10.1158/1535-7163.22510647
Autor:
Alison H. Banham, Adrian L. Harris, Penny A. Handford, Nicola R. Sibson, James Larkin, Manuel Sarmiento-Soto, Sébastien Serres, Devon Sheppard, Chandramouli Chillakuri, Ji-Liang Li, Ellen Bealing, Jenna Yates, Stephen Stribbling, Sarah Watts, Tasneem Hassanali, Jenny Greig, Carol Bentley, Pat Whiteman, Demin Li, Massimo Masiero
Supplementary material and methods. Supplementary table 1: cell lines and growth conditions. Supplementary table 2: Notch ligands and control protein for plate coating. Supplementary table 3: qPCR primers. Supplementary table 4: flow cytometry antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7722864810fcbbbc5d915df61ec1c5
https://doi.org/10.1158/1535-7163.22510644
https://doi.org/10.1158/1535-7163.22510644
Autor:
Alison H. Banham, Adrian L. Harris, Penny A. Handford, Nicola R. Sibson, James Larkin, Manuel Sarmiento-Soto, Sébastien Serres, Devon Sheppard, Chandramouli Chillakuri, Ji-Liang Li, Ellen Bealing, Jenna Yates, Stephen Stribbling, Sarah Watts, Tasneem Hassanali, Jenny Greig, Carol Bentley, Pat Whiteman, Demin Li, Massimo Masiero
The role of Notch signaling and its ligand JAGGED1 (JAG1) in tumor biology has been firmly established, making them appealing therapeutic targets for cancer treatment. Here, we report the development and characterization of human/rat-specific JAG1-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4eef16695f97e97c7b4771d67bccc53
https://doi.org/10.1158/1535-7163.c.6539670
https://doi.org/10.1158/1535-7163.c.6539670
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 59:211-212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a225dc976bac480148c0bc4d96d4e7b0
https://doi.org/10.1177/00045632211066761
https://doi.org/10.1177/00045632211066761
