Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Ellen A, Schur"'
Autor:
Megan Herodes, Lindsey J. Anderson, Samuel Shober, Ellen A. Schur, Solomon A. Graf, Nicola Ammer, Ramiro Salas, Marco Marcelli, Jose M. Garcia
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 835-846 (2023)
Abstract Background Cancer cachexia is associated with reduced body weight, appetite and quality of life (QOL) with no approved treatments. Growth hormone secretagogues like macimorelin have potential to mitigate these effects. Methods This pilot stu
Externí odkaz:
https://doaj.org/article/be56647d07604dabab7f078a1659e5a8
Autor:
Mauricio D. Dorfman, Thomas Monfeuga, Susan J. Melhorn, Jenny E. Kanter, Jeremy M. Frey, Rachael D. Fasnacht, Anandhakumar Chandran, Emaad Lala, Inmaculada Velasco, Katya B. Rubinow, Thomas H. Meek, Ellen A. Schur, Karin E. Bornfeldt, Joshua P. Thaler
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E461-E475
This study provides evidence that hypothalamic gliosis is a key early event through which androgen deficiency in combination with a Western-style diet might lead to cardiometabolic dysregulation in males. Furthermore, this work provides the first evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cf192827031d3cb0f0a3266ee84dbd
https://doi.org/10.1152/ajpendo.00059.2023
https://doi.org/10.1152/ajpendo.00059.2023
Autor:
Samantha L. Martin, Michelle I. Cardel, Tiffany L. Carson, James O. Hill, Takara Stanley, Steven Grinspoon, Felicia Steger, Loneke T. Blackman Carr, Maxine Ashby-Thompson, Delisha Stewart, Jamy Ard, Fatima Cody Stanford, Raziel Rojas-Rodriguez, Mabel Toribio, Gabrielle Page-Wilson, Ursula White, Glenn Rowe, Marine Saint-Cyr, Rita Brookheart, Lauren Adele Fowler, Gwen Twillman, Felicia Price, April Stull, Sonia Vega-Lopez, Tony Comuzzie, Catherine M. Kotz, Francoise Knox Kazimierczuk, Monica L. Baskin, Robert Newton, Andrew Greenberg, Camile E. Powe, Dympna Gallagher, David H. Burk, Elissa S. Epel, Paul S. MacLean, Kimberly P. Truesdale, Dominic N. Reeds, Ellen A. Schur, Nicole P. Redmond, Minor L. Cushion
Publikováno v:
The American Journal of Clinical Nutrition. 117:659-671
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35bdf71bd2f8830d0ac9b3b1ccc64b79
https://doi.org/10.1016/j.ajcnut.2023.02.001
https://doi.org/10.1016/j.ajcnut.2023.02.001
Autor:
Leticia E Sewaybricker, Alyssa Huang, Suchitra Chandrasekaran, Susan J Melhorn, Ellen A Schur
Publikováno v:
Endocr Rev
Accumulated preclinical literature demonstrates that hypothalamic inflammation and gliosis are underlying causal components of diet-induced obesity in rodent models. This review summarizes and synthesizes available translational data to better unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca49a26747616e42ab8576665d0595f
https://doi.org/10.1210/endrev/bnac023
https://doi.org/10.1210/endrev/bnac023
Autor:
Imen Becetti, Esther L Bwenyi, Ivan E de Araujo, Jamy Ard, John F Cryan, Ismaa Sadaf Farooqi, Carrie R Ferrario, Marci E Gluck, Laura M Holsen, Paul J Kenny, Elizabeth A Lawson, Bradford B Lowell, Ellen A Schur, Takara L Stanley, Ali Tavakkoli, Steven K Grinspoon, Vibha Singhal
Publikováno v:
The American Journal of Clinical Nutrition
Obesity is increasing at an alarming rate. The effectiveness of currently available strategies for the treatment of obesity (including pharmacologic, surgical, and behavioral interventions) is limited. Understanding the neurobiology of appetite and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e169351582fecd10af433a3178104f
https://doi.org/10.1016/j.ajcnut.2023.05.003
https://doi.org/10.1016/j.ajcnut.2023.05.003
Autor:
Cornelia M. Ulrich, Anne McTiernan, Catherine Duggan, Ching-Yun Wang, Martin Morgan, Jerry Davison, Liren Xiao, Ling-Yu Kuan, Clare Abbenhardt, Marc Horton, Nina Habermann, Ellen A. Schur, Derek Hagman, Mario Kratz, Karen W. Makar, Karen E. Foster-Schubert, Kristin L. Campbell
Supplementary Figure 1 PDF file - 184K, Differential gene expression analyzed by intervention group. Heat map displaying the gene expression change of 82 candidate genes in control individuals compared to those in the diet, exercise, and diet+exercis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5437a174e47fd19459dbf48bbcbe2c64
https://doi.org/10.1158/1940-6207.22525572
https://doi.org/10.1158/1940-6207.22525572
Autor:
Cornelia M. Ulrich, Anne McTiernan, Catherine Duggan, Ching-Yun Wang, Martin Morgan, Jerry Davison, Liren Xiao, Ling-Yu Kuan, Clare Abbenhardt, Marc Horton, Nina Habermann, Ellen A. Schur, Derek Hagman, Mario Kratz, Karen W. Makar, Karen E. Foster-Schubert, Kristin L. Campbell
Adipose tissue plays a role in obesity-related cancers via increased production of inflammatory factors, steroid hormones, and altered adipokines. The impact of weight loss on adipose tissue gene expression may provide insights into pathways linking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d7238ca0339abe1b9edaa658018314
https://doi.org/10.1158/1940-6207.c.6544803
https://doi.org/10.1158/1940-6207.c.6544803
Autor:
Cornelia M. Ulrich, Anne McTiernan, Catherine Duggan, Ching-Yun Wang, Martin Morgan, Jerry Davison, Liren Xiao, Ling-Yu Kuan, Clare Abbenhardt, Marc Horton, Nina Habermann, Ellen A. Schur, Derek Hagman, Mario Kratz, Karen W. Makar, Karen E. Foster-Schubert, Kristin L. Campbell
Supplementary Figure 2 PDF file - 147K, qRT-PCR validation of microarray results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0423629d8700b80ea0bf943b2fef3705
https://doi.org/10.1158/1940-6207.22525569.v1
https://doi.org/10.1158/1940-6207.22525569.v1
Autor:
Christian L Roth, Susan J Melhorn, Mary Rosalynn B De Leon, Maya G Rowland, Clinton T Elfers, Alyssa Huang, Brian E Saelens, Ellen A Schur
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:2254-2266
Context Obesity interventions often result in increased motivation to eat. Objective We investigated relationships between obesity outcomes and changes in brain activation by visual food cues and hormone levels in response to obesity intervention by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63b2124eb031b4cca719f46c2e1cfdb
https://doi.org/10.1210/clinem/dgac299
https://doi.org/10.1210/clinem/dgac299
Evidence That Hypothalamic Gliosis Is Related to Impaired Glucose Homeostasis in Adults With Obesity
Autor:
Mary Rosalynn B. De Leon, Stefan Schoen, Ellen A. Schur, Kristina M. Utzschneider, Madelaine Humphreys, Susan J. Melhorn, Jennifer L. Rosenbaum, Mary F. Webb
Publikováno v:
Diabetes Care
OBJECTIVE Preclinical research implicates hypothalamic glial cell responses in the pathogenesis of obesity and type 2 diabetes (T2D). In the current study we sought to translate such findings to humans by testing whether radiologic markers of gliosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3bda2e87f728a6e28413cb02a7481a
https://doi.org/10.2337/dc21-1535
https://doi.org/10.2337/dc21-1535