A New Behavioral Paradigm for Frustrative Nonreward in Juvenile Mice

Autor: Aijaz Ahmad Naik, Xiaoyu Ma, Maxime Munyeshyaka, Ellen Leibenluft, Zheng Li

Publikováno v: Biological Psychiatry Global Open Science, Vol 4, Iss 1, Pp 31-38 (2024)

Background: Irritability, defined as proneness to anger, can reach a pathological extent. It is a defining symptom of disruptive mood dysregulation disorder and one of the most common reasons youths present for psychiatric evaluation and care. Aberra

Externí odkaz: https://doaj.org/article/859463c520ab493a95e2f761ecc94a6a

BOLD Response is more than just magnitude: Improving detection sensitivity through capturing hemodynamic profiles

Autor: Gang Chen, Paul A. Taylor, Richard C. Reynolds, Ellen Leibenluft, Daniel S. Pine, Melissa A. Brotman, David Pagliaccio, Simone P. Haller

Publikováno v: NeuroImage, Vol 277, Iss , Pp 120224- (2023)

Typical fMRI analyses often assume a canonical hemodynamic response function (HRF) that primarily focuses on the peak height of the overshoot, neglecting other morphological aspects. Consequently, reported analyses often reduce the overall response c

Externí odkaz: https://doaj.org/article/b9f21ef6c76e43ce8ffeae50d57347b8

Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group

Autor: Anita Harrewijn, Elise M. Cardinale, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Moji Aghajani, Kevin Hilbert, Narcis Cardoner, Daniel Porta-Casteràs, Savannah Gosnell, Ramiro Salas, Andrea P. Jackowski, Pedro M. Pan, Giovanni A. Salum, Karina S. Blair, James R. Blair, Mira Z. Hammoud, Mohammed R. Milad, Katie L. Burkhouse, K. Luan Phan, Heidi K. Schroeder, Jeffrey R. Strawn, Katja Beesdo-Baum, Neda Jahanshad, Sophia I. Thomopoulos, Randy Buckner, Jared A. Nielsen, Jordan W. Smoller, Jair C. Soares, Benson Mwangi, Mon-Ju Wu, Giovana B. Zunta-Soares, Michal Assaf, Gretchen J. Diefenbach, Paolo Brambilla, Eleonora Maggioni, David Hofmann, Thomas Straube, Carmen Andreescu, Rachel Berta, Erica Tamburo, Rebecca B. Price, Gisele G. Manfro, Federica Agosta, Elisa Canu, Camilla Cividini, Massimo Filippi, Milutin Kostić, Ana Munjiza Jovanovic, Bianca A. V. Alberton, Brenda Benson, Gabrielle F. Freitag, Courtney A. Filippi, Andrea L. Gold, Ellen Leibenluft, Grace V. Ringlein, Kathryn E. Werwath, Hannah Zwiebel, André Zugman, Hans J. Grabe, Sandra Van der Auwera, Katharina Wittfeld, Henry Völzke, Robin Bülow, Nicholas L. Balderston, Monique Ernst, Christian Grillon, Lilianne R. Mujica-Parodi, Helena van Nieuwenhuizen, Hugo D. Critchley, Elena Makovac, Matteo Mancini, Frances Meeten, Cristina Ottaviani, Tali M. Ball, Gregory A. Fonzo, Martin P. Paulus, Murray B. Stein, Raquel E. Gur, Ruben C. Gur, Antonia N. Kaczkurkin, Bart Larsen, Theodore D. Satterthwaite, Jennifer Harper, Michael Myers, Michael T. Perino, Chad M. Sylvester, Qiongru Yu, Ulrike Lueken, Dick J. Veltman, Paul M. Thompson, Dan J. Stein, Nic J. A. Van der Wee, Anderson M. Winkler, Daniel S. Pine

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract The goal of this study was to compare brain structure between individuals with generalized anxiety disorder (GAD) and healthy controls. Previous studies have generated inconsistent findings, possibly due to small sample sizes, or clinical/an

Externí odkaz: https://doaj.org/article/9d17f9f8582240abad7553d20434e213

Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans

Autor: Rany Abend, Diana Burk, Sonia G Ruiz, Andrea L Gold, Julia L Napoli, Jennifer C Britton, Kalina J Michalska, Tomer Shechner, Anderson M Winkler, Ellen Leibenluft, Daniel S Pine, Bruno B Averbeck

Publikováno v: eLife, Vol 11 (2022)

Influential theories implicate variations in the mechanisms supporting threat learning in the severity of anxiety symptoms. We use computational models of associative learning in conjunction with structural imaging to explicate links among the mechan

Externí odkaz: https://doaj.org/article/5b3aa938365a4b8087e01b6b9ee84297

Characterizing the Neural Correlates of Response Inhibition and Error Processing in Children With Symptoms of Irritability and/or Attention-Deficit/Hyperactivity Disorder in the ABCD Study®

Autor: Ka Shu Lee, Jingyuan Xiao, Jiajun Luo, Ellen Leibenluft, Zeyan Liew, Wan-Ling Tseng

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

Attention-deficit/hyperactivity disorder (ADHD), characterized by symptoms of inattention and/or hyperactivity and impulsivity, is a neurodevelopmental disorder associated with executive dysfunctions, including response inhibition and error processin

Externí odkaz: https://doaj.org/article/f893285f1de04b0880244addf604670e