Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ella Pfaff"'
Autor:
Kenneth R. Olson, Tsuyoshi Takata, Kasey J. Clear, Yan Gao, Zhilin Ma, Ella Pfaff, Karthik Mouli, Thomas A. Kent, Prentiss Jones, Jon Fukuto, Gang Wu, Karl D. Straub
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 991 (2024)
LCS-1, a putative selective inhibitor of SOD1, is a substituted pyridazinone with rudimentary similarity to quinones and naphthoquinones. As quinones catalytically oxidize H2S to biologically active reactive sulfur species (RSS), we hypothesized LCS-
Externí odkaz:
https://doaj.org/article/0d5f005ab7d049c997866a406f49cb60
Autor:
Kenneth R. Olson, Kasey J. Clear, Tsuyoshi Takata, Yan Gao, Zhilin Ma, Ella Pfaff, Anthony Travlos, Jennifer Luu, Katherine Wilson, Zachary Joseph, Ian Kyle, Stephen M. Kasko, Prentiss Jones Jr, Jon Fukuto, Ming Xian, Gang Wu, Karl D. Straub
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 619 (2024)
1,4-naphthoquinones (NQs) catalytically oxidize H2S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can form NQ-SH adducts through Michael addition. Here, we measured oxygen consumption and used sulfur-s
Externí odkaz:
https://doaj.org/article/b9f3829de87f408da4dfd508b189a2b0
Autor:
Kenneth R. Olson, Kasey J. Clear, Yan Gao, Zhilin Ma, Nathaniel M. Cieplik, Alyssa R. Fiume, Dominic J. Gaziano, Stephen M. Kasko, Jennifer Luu, Ella Pfaff, Anthony Travlos, Cecilia Velander, Katherine J. Wilson, Elizabeth D. Edwards, Karl D. Straub, Gang Wu
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7516
Naphthoquinone (1,4-NQ) and its derivatives (NQs, juglone, plumbagin, 2-methoxy-1,4-NQ, and menadione) have a variety of therapeutic applications, many of which are attributed to redox cycling and the production of reactive oxygen species (ROS). We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd306ff03c6371db2f39b7873fa0c50
Autor:
Kenneth R, Olson, Kasey J, Clear, Paul J, Derry, Yan, Gao, Zhilin, Ma, Nathaniel M, Cieplik, Alyssa, Fiume, Dominic J, Gaziano, Stephen M, Kasko, Kathleen, Narloch, Cecilia L, Velander, Ifeyinwa, Nwebube, Collin J, Pallissery, Ella, Pfaff, Brian P, Villa, Thomas A, Kent, Gang, Wu, Karl D, Straub
Publikováno v:
International journal of molecular sciences. 23(21)
1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of adducts with regulatory protein thiols. Reactive sulfur species (RSS) are chemically and bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bda426d3228d7569612812fd21bfbe47
https://pubmed.ncbi.nlm.nih.gov/36362080
https://pubmed.ncbi.nlm.nih.gov/36362080
Autor:
Kenneth R. Olson, Kasey J. Clear, Paul J. Derry, Yan Gao, Zhilin Ma, Nathaniel M. Cieplik, Alyssa Fiume, Dominic J. Gaziano, Stephen M. Kasko, Kathleen Narloch, Cecilia L. Velander, Ifeyinwa Nwebube, Collin J. Pallissery, Ella Pfaff, Brian P. Villa, Thomas A. Kent, Gang Wu, Karl D. Straub
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13293
1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of adducts with regulatory protein thiols. Reactive sulfur species (RSS) are chemically and bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddca67dae2ae6828d376c11a4e9c193
https://doi.org/10.3390/ijms232113293
https://doi.org/10.3390/ijms232113293