Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ella A. Meleshkevitch"'
Autor:
Matthew D. Strub, Shyam Ramachandran, Dmitri Y. Boudko, Ella A. Meleshkevitch, Alejandro A. Pezzulo, Aravind Subramanian, Arthur Liberzon, Robert J. Bridges, Paul B. McCray Jr.
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 2, Pp 240-251 (2022)
Abstract Cystic fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The common ΔF508‐CFTR mutation results in protein misfolding and proteasomal degradat
Externí odkaz:
https://doaj.org/article/118b9841113341758b26c7d71659a1be
Autor:
Rachel A. Hodos, Matthew D. Strub, Shyam Ramachandran, Ella A. Meleshkevitch, Dmitri Y. Boudko, Robert J. Bridges, Joel T. Dudley, Paul B. McCray Jr.
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 5, Pp 500-510 (2021)
Abstract Rare diseases affect 10% of the first‐world population, yet over 95% lack even a single pharmaceutical treatment. In the present age of information, we need ways to leverage our vast data and knowledge to streamline therapeutic development
Externí odkaz:
https://doaj.org/article/35af72e80c624b9c9410aa56577a0eb6
Autor:
Matthew D. Strub, Shyam Ramachandran, Dmitri Y. Boudko, Ella A. Meleshkevitch, Alejandro A. Pezzulo, Aravind Subramanian, Arthur Liberzon, Robert J. Bridges, Paul B. McCray
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 2, Pp 240-251 (2022)
Cystic fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The common ΔF508‐CFTR mutation results in protein misfolding and proteasomal degradation. If
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69927bce9f5a70344d83ee3912fc5e1
https://doi.org/10.1002/psp4.12751
https://doi.org/10.1002/psp4.12751
Autor:
Naila O Alieva, Karen A Konzen, Steven F Field, Ella A Meleshkevitch, Marguerite E Hunt, Victor Beltran-Ramirez, David J Miller, Jörg Wiedenmann, Anya Salih, Mikhail V Matz
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2680 (2008)
GFP-like fluorescent proteins (FPs) are the key color determinants in reef-building corals (class Anthozoa, order Scleractinia) and are of considerable interest as potential genetically encoded fluorescent labels. Here we report 40 additional members
Externí odkaz:
https://doaj.org/article/04ca605a135d4b5583df68d4b8d61b50
Autor:
Dmitri A. Voronov, Ryan Metzler, Melissa M. Miller, Jeffrey M. Fox, Dmitri Y. Boudko, Maria Penneda, Ella A. Meleshkevitch
Publikováno v:
Insect Biochemistry and Molecular Biology. 43:755-767
AeNAT5 (NCBI, {"type":"entrez-protein","attrs":{"text":"ABZ81822","term_id":"167515094","term_text":"ABZ81822"}}ABZ81822), an orphan member of the insect-specific Nutrient Amino acid Transporter subfamily of SoLute Carrier family 6 (NAT-SLC6) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb92d37fc5b21469306a03ff1cff4cca
https://doi.org/10.1016/j.ibmb.2013.05.008
https://doi.org/10.1016/j.ibmb.2013.05.008
Autor:
Immo A. Hansen, Geoffrey M. Attardo, Alexander S. Raikhel, Ella A. Meleshkevitch, Sarah E. Aguirre, Jeffery Fox, Lisa L. Drake, Dmitri A. Voronov, Dmitri Y. Boudko, Shin-Hong Shiao
Publikováno v:
Journal of Biological Chemistry. 286:10803-10813
Insect yolk protein precursor gene expression is regulated by nutritional and endocrine signals. A surge of amino acids in the hemolymph of blood-fed female mosquitoes activates a nutrient signaling system in the fat bodies, which subsequently derepr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080b7657a8f7822dace6d67f02547b04
https://doi.org/10.1074/jbc.m110.179739
https://doi.org/10.1074/jbc.m110.179739
Autor:
Melissa M. Miller, Marvin Robinson, Dmitri Y. Boudko, Lyudmila B. Popova, Ella A. Meleshkevitch, William R. Harvey
Publikováno v:
Journal of Experimental Biology. 212:1559-1567
SUMMARY The nutrient amino acid transporter (NAT) subfamily of the neurotransmitter sodium symporter family (NSS, also known as the solute carrier family 6, SLC6)represents transport mechanisms with putative synergistic roles in the absorption of ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c2c4fe7fc1be6ff4fae3ac84b16dc6
https://doi.org/10.1242/jeb.027383
https://doi.org/10.1242/jeb.027383
Autor:
Ella A. Meleshkevitch, Dmitri Y. Boudko, Lyudmila B. Popova, Philip V. Tran, Melissa M. Miller
Publikováno v:
Insect Biochemistry and Molecular Biology. 38:923-931
The CG3252 gene product, DmNAT1, represents the first Nutrient Amino acid Transporter cloned from Drosophila . It absorbs a broader set of neutral amino acids versus earlier characterized insect NATs and mammalian NATs-B 0 system transporters from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86c09fe99b2c3dd4d65e286e1f8ed82
https://doi.org/10.1016/j.ibmb.2008.07.005
https://doi.org/10.1016/j.ibmb.2008.07.005
Autor:
Gregory A. Ahearn, A. Mandal, S. C. Arunachalam, P. K. Mandal, Dmitri Y. Boudko, Ella A. Meleshkevitch
Publikováno v:
Journal of Comparative Physiology B. 179:205-214
We have previously reported on calcium transport mechanisms in American lobster, Homarus americanus, using (45)Ca(2+) coupled with vesicle preparations of hepatopancreatic endoplasmic reticulum. The active transport of calcium across membranes border
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f83e45f5a1ed507994109acfb161b5
https://doi.org/10.1007/s00360-008-0303-7
https://doi.org/10.1007/s00360-008-0303-7
Autor:
Stephen B. W. Keen, Bernard A. Okech, Ella A. Meleshkevitch, Melissa M. Miller, Paul J. Linser, Mark R. Rheault, Dmitri Y. Boudko, William R. Harvey
Publikováno v:
Journal of Experimental Biology. 210:3848-3861
SUMMARYWe have cloned a cDNA encoding a new ion transporter from the alimentary canal of larval African malaria mosquito, Anopheles gambiae Giles sensu stricto. Phylogenetic analysis revealed that the corresponding gene is in a group that has been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c178f33c2cc2d1a0ce286dd4a1eb33
https://doi.org/10.1242/jeb.007872
https://doi.org/10.1242/jeb.007872