Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ella, Zeldich"'
Autor:
Ella Zeldich, Sandeep Rajkumar
Publikováno v:
Cells, Vol 13, Iss 8, p 674 (2024)
Oligodendrocytes originating in the brain and spinal cord as well as in the ventral and dorsal domains of the neural tube are transcriptomically and functionally distinct. These distinctions are also reflected in the ultrastructure of the produced my
Externí odkaz:
https://doaj.org/article/14a4f39368634859a17553d5742b1458
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-27 (2022)
Abstract Intellectual disability is a well-known hallmark of Down Syndrome (DS) that results from the triplication of the critical region of human chromosome 21 (HSA21). Major studies were conducted in recent years to gain an understanding about the
Externí odkaz:
https://doaj.org/article/d3556d7e9d724bfcbb0bc845bba457ce
Autor:
Zhen Li, Jenny A. Klein, Sanjeev Rampam, Ronni Kurzion, Natalie Baker Campbell, Yesha Patel, Tarik F. Haydar, Ella Zeldich
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The intellectual disability (ID) in Down syndrome (DS) is thought to result from a variety of developmental deficits such as alterations in neural progenitor division, neurogenesis, gliogenesis, cortical architecture, and reduced cortical volume. How
Externí odkaz:
https://doaj.org/article/67f9da21a494489798d3e6a36b394920
Autor:
Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myel
Externí odkaz:
https://doaj.org/article/d0316aa1c81f46c48fea6d9bd65cb877
Autor:
Ci-Di Chen, Yuexuan Li, Arthur K Chen, Melissa A Rudy, Jason S Nasse, Ella Zeldich, Taryn J Polanco, Carmela R Abraham
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226382 (2020)
Klotho is an age-extending, cognition-enhancing protein found to be down-regulated in aged mammals when age-related diseases start to appear. Low levels of Klotho occur in neurodegenerative diseases, kidney disease and many cancers. Many normal and p
Externí odkaz:
https://doaj.org/article/4bfff10d5b234cd68fb0ae137b1cc0f3
Autor:
Tammi Arbel Rubinstein, Inbal Reuveni, Arkadi Hesin, Anat Klein-Goldberg, Hannes Olauson, Tobias E. Larsson, Carmela R. Abraham, Ella Zeldich, Assumpció Bosch, Miguel Chillón, Kenneth Samuel Hollander, Ayelet Shabtay-Orbach, Gilad W. Vainer, Ido Wolf, Tami Rubinek
Publikováno v:
Cancers, Vol 13, Iss 6297, p 6297 (2021)
Cancers; Volume 13; Issue 24; Pages: 6297
Cancers
Scientia
Cancers; Volume 13; Issue 24; Pages: 6297
Cancers
Scientia
Simple Summary We aimed to study the role of the anti-aging protein klotho and its secreted isoform, sKL, in pancreatic cancer. Three in vivo models, including a novel genetic mouse model and bioinformatics analyses, indicated klotho as a tumor suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7840f90fb214a509b478b4a541aae8
https://www.mdpi.com/2072-6694/13/24/6297
https://www.mdpi.com/2072-6694/13/24/6297
Autor:
Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e1e167eaf3d681b4fc99f999f192a1
https://pubmed.ncbi.nlm.nih.gov/35058753
https://pubmed.ncbi.nlm.nih.gov/35058753
Autor:
Nelson C. Lau, Bryce Howat, Anthony G. Lambert, Theo Hatzipetros, Ann C. McKee, Qicheng Ma, Ci-Di Chen, Dean Zeldich, Emma Boden, Ella Zeldich, Carmela R. Abraham, Jason S. Nasse, Jonathan D. Cherry, Rebecca M. Mathias, Andrea Yuste
Publikováno v:
Journal of Molecular Neuroscience. 69:264-285
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the loss of motor neurons in the brain and spinal cord. ALS neuropathology is associated with increased oxidative stress, excitotoxicity, and inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7a3a07ad1a089f894311907c475f99
https://doi.org/10.1007/s12031-019-01356-2
https://doi.org/10.1007/s12031-019-01356-2
Autor:
Ella Zeldich, Samantha M Shelton, Ronni Kurzion, Tarik F. Haydar, John H Connor, Alexandra R Soucy
Publikováno v:
eNeuro
Prenatal exposure to Zika virus (ZIKV) can result in microencephaly and congenital Zika syndrome, though some brain cells and structures are spared by the virus for unknown reasons. Here, a novel murine model of fetal ZIKV infection incorporating int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9256265f8045df54dd73000f88a9af27
https://pubmed.ncbi.nlm.nih.gov/34272257
https://pubmed.ncbi.nlm.nih.gov/34272257
Autor:
Mayumi Okamoto, Tianliuyun Gao, William A. Tyler, Zhen Li, Nenad Sestan, Ella Zeldich, Mingfeng Li, Gabriel Santpere Baró, Tarik F. Haydar
Publikováno v:
Science Advances
Mouse and human cortical progenitors share marked similarities; crucial differences instruct species-specific differentiation.
How the rich variety of neurons in the nervous system arises from neural stem cells is not well understood. Using sing
How the rich variety of neurons in the nervous system arises from neural stem cells is not well understood. Using sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f742f3caa59f0240fe111c470e3536
https://pubmed.ncbi.nlm.nih.gov/33158872
https://pubmed.ncbi.nlm.nih.gov/33158872