Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elke Zwanziger"'
Autor:
Leo Yi Yang Lee, Jie Zhou, Rebecca Frise, Daniel H Goldhill, Paulina Koszalka, Edin J Mifsud, Kaoru Baba, Takahiro Noda, Yoshinori Ando, Kenji Sato, Aoe-Ishikawa Yuki, Takao Shishido, Takeki Uehara, Steffen Wildum, Elke Zwanziger, Neil Collinson, Klaus Kuhlbusch, Barry Clinch, Aeron C Hurt, Wendy S Barclay
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008395 (2020)
Influenza viruses cause seasonal outbreaks and pose a continuous pandemic threat. Although vaccines are available for influenza control, their efficacy varies each season and a vaccine for a novel pandemic virus manufactured using current technology
Externí odkaz:
https://doaj.org/article/61b97708882143f882083c1fe0a052d6
Autor:
Patanjali Ravva, Annabelle Lemenuel-Diot, Rajinder Bhardwaj, Clare Nasmyth-Miller, Steve Dang, Patrick F. Smith, Elke Zwanziger, Stefan Sturm, Kashyap Patel, Leonid Gibiansky
Publikováno v:
British Journal of Clinical Pharmacology
Aim Pharmacologic effects were analysed to determine a dose recommendation for oseltamivir in immunocompromised (IC) adults with influenza. Methods Quantitative clinical pharmacology methods were applied to data from 160 adult IC patients (aged 18-78
Autor:
Barry Clinch, Stefan Sturm, Elke Zwanziger, Leonid Gibiansky, Paul Grimsey, Patanjali Ravva, Neil Parrott, Rajinder Bhardwaj
Publikováno v:
Clinical Pharmacology and Therapeutics
A mechanistic population‐pharmacokinetic model was developed to predict oseltamivir exposures in neonates and infants accounting for physiological changes during the first 2 years of life. The model included data from 13 studies, comprising 436 sub
Autor:
Leonid Gibiansky, Jules Hernández-Sánchez, Sebastien Jolivet, Annabelle Lemenuel-Diot, Rajinder Bhardwaj, Stefan Sturm, Timothy Knab, Patanjali Ravva, Eric Burroughs Jordie, Elke Zwanziger, Clare Nasmyth-Miller
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 88(3)
AIMS To optimise the dosing regimen of oseltamivir for immunocompromised (IC) paediatric patients (
Publikováno v:
Bioanalysis. 12(21)
Autor:
Erica Winter, Sameeh Salama, Akiko Kano, Navita L. Mallalieu, Ignacio Rodriguez, Anna Maria Geretti, Darren Bentley, Gemma Attley, Katie Patel, Scott Fettner, Elke Zwanziger
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial agents and chemotherapy
Antimicrobial agents and chemotherapy
Nacubactam is a novel β-lactamase inhibitor with dual mechanisms of action as an inhibitor of serine β-lactamases (classes A and C and some class D) and an inhibitor of penicillin binding protein 2 in Enterobacteriaceae. The safety, tolerability, a
Publikováno v:
Bioanalysis. 11(18)
Aim: Monitoring the internal standard (IS) response is common practice in bioanalysis by LC–MS/MS. IS response variation may raise questions on assay quality and should trigger investigations into the root cause. Results: In two case studies with I
Autor:
Paulina Koszalka, Neil Collinson, Kenji Sato, Jie Zhou, Klaus Kuhlbusch, Barry Clinch, Rebecca Frise, Takeki Uehara, Steffen Wildum, Elke Zwanziger, Daniel H. Goldhill, Aoe-Ishikawa Yuki, Takahiro Noda, Kaoru Baba, Aeron C. Hurt, Wendy S. Barclay, Takao Shishido, Edin J Mifsud, Yoshinori Ando, Leo Yi Yang Lee
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008395 (2020)
PLoS Pathogens, Vol 16, Iss 4, p e1008395 (2020)
Influenza viruses cause seasonal outbreaks and pose a continuous pandemic threat. Although vaccines are available for influenza control, their efficacy varies each season and a vaccine for a novel pandemic virus manufactured using current technology
Publikováno v:
Bioanalysis. 7(3)
In bioanalysis of small molecules, the analyte concentration in the measured samples should reflect the concentration during sample collection. Precautions may be needed to prevent over- or under-estimation of the obtained result. This might require
Publikováno v:
Bioanalysis. 5(15)