Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Elke Walter"'
Publikováno v:
CHIMIA, Vol 55, Iss 3 (2001)
The chemical conjugation or the physical embodiment of therapeutic agents in polymers offers great potential to improve the efficacy and safety of therapies and create novel therapeutic opportunities. This has led to numerous concepts regarding the f
Externí odkaz:
https://doaj.org/article/5a25222d69994efeade5bdb9f619fcb7
Autor:
Camilo J Acosta, Clemente Diaz, Francesco Nordio, Htay-Htay Han, Kelley J Moss, Kelly Bohning, Pradeep Kumar, Mengya Liu, Hetal Patel, Filippo Pacciarini, Vincent Mwangi, Elke Walter, Tim D Powell, Hana M El Sahly, Whitney R Baldwin, Joseph Santangelo, Evan J Anderson, Gary Dubin
Publikováno v:
The Journal of infectious diseases.
Background We report 2-year persistence of immune response to Takeda's prophylactic purified formalin-inactivated whole Zika virus vaccine candidate (TAK-426) compared with that observed after natural infection. Methods A randomized, observer-blind,
Autor:
Elke Walter
Dieser unkonventionelle Sprachführer erklärt die Sprache des irischen Alltags – so, wie sie normalerweise nicht im Wörterbuch steht: Sprüche, Floskeln und Frotzeleien, Sprichwörter, Trinksprüche, Schimpf- und Kosewörter, Verballhornungen, Kr
Publikováno v:
Journal of Microencapsulation. 21:25-36
Technical aspects for preparing a new type of cationic stearylamine (SA)-containing microparticle as a potential drug delivery system for negatively charged therapeutics were investigated. Cationic biodegradable microparticles based on poly(lactide)
Autor:
Marcus Textor, Nicholas D. Spencer, Markus Müller, Gaudenz Danuser, Elke Walter, Hans P. Merkle, Janos Vörös, Gabor Csucs
Publikováno v:
Journal of Biomedical Materials Research Part A. :55-61
Microspheres made of poly(lactic-co-glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro- and nanospheres is a mai
Publikováno v:
Pharmaceutical Research. 20:237-246
Purpose. The purpose of this study was to demonstrate specific receptor-mediated targeting of phagocytes by functional surface coatings of microparticles, shielding from nonspecific phagocytosis and allowing ligand-specific interactions via molecular
Publikováno v:
Pharmaceutical Research. 20:221-228
Purpose. We compared cationic, polyamine-coated microparticles (MPs) and anionic, protein-coated MPs with respect to their phagocytosis and phagosomal fate in dendritic cells (DCs) and macrophages (MΦ).
Publikováno v:
Biomaterials. 23:4667-4676
Biodegradable microparticles represent a promising carrier system for the efficient delivery of therapeutic macromolecules to phagocytic professional antigen-presenting cells (APC). Solid lipid microparticles (SLM) consisting of a tripalmitin matrix
Publikováno v:
Expert Review of Vaccines. 1:215-226
Therapeutic prospects of particulates are increasingly recognized for vaccination purposes. Compared with biologic particulates, such as live or attenuated bacterial vectors and viral vectors, synthetic particulates may be expected to ease the hurdle
Publikováno v:
European Journal of Pharmaceutical Sciences. 15:39-47
Excised porcine intestinal tissue obtained from the local abattoir was studied for its suitability to examine the uptake and transport of poly(lactic-co-glycolic acid) (PLGA) nanoparticles in Peyer's (PP) and non-Peyer's patch (NPP) tissue in vitro.