Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elke Vanden Eynden"'
Autor:
Annerieke Sierksma, Ashley Lu, Evgenia Salta, Elke Vanden Eynden, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, David Blum, Luc Buée, Mark Fiers, Bart De Strooper
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-15 (2018)
Abstract Background Despite diverging levels of amyloid-β (Aβ) and TAU pathology, different mouse models, as well as sporadic AD patients show predictable patterns of episodic memory loss. MicroRNA (miRNA) deregulation is well established in AD bra
Externí odkaz:
https://doaj.org/article/5b299d246bfe4e12b8032f1dd8510539
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 9, Pp 1005-1018 (2016)
Abstract microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐promoting functions in the nervous system and has been found consistently downregulated in Alzheimer's disease (AD). Whether and how miR‐132 deficiency
Externí odkaz:
https://doaj.org/article/f521c62afe5f42edbe64337d8bb51b38
Autor:
Yannick Fourne, Sandrine Thuret, Mark Fiers, Sriram Balusu, Zsuzsanna Callaerts-Vegh, Carlo Sala Frigerio, Evgenia Salta, Katleen Craessaerts, Edina Silajdžić, Dietmar Rudolf Thal, Katrien Horré, Hannah Walgrave, Nicky Thrupp, Leen Wolfs, Bart De Strooper, Sarah Snoeck, Rudi D Hooge, Elke Vanden Eynden, Henrik Zetterberg, Alicja Ronisz
SummaryAdult hippocampal neurogenesis (AHN) plays a crucial role in memory processes and is impeded in the brains of Alzheimer’s disease (AD) patients. However, the molecular mechanisms impacting AHN in AD brain are unknown. Here we identify miR-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374e8397a45690b541740d8724a822e9
https://doi.org/10.1101/2020.03.12.988709
https://doi.org/10.1101/2020.03.12.988709
Publikováno v:
EMBO Molecular Medicine
microRNA-132 (miR-132) is involved in prosurvival, anti-inflammatory and memory-promoting functions in the nervous system and has been found consistently downregulated in Alzheimer's disease (AD). Whether and how miR-132 deficiency impacts AD patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f1f677c6d74149fb5be539707ecee8
https://doi.org/10.15252/emmm.201606520
https://doi.org/10.15252/emmm.201606520
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f1c7529dcd48fda1bb8e40671bf85f9
https://doi.org/10.1016/j.jalz.2017.07.349
https://doi.org/10.1016/j.jalz.2017.07.349
Autor:
John Hardy, Karelle Leroy, Elke Vanden Eynden, Ira Espuny-Camacho, Sebastian Munck, Enrico Radaelli, Amaia M. Arranz, Ina Tesseur, Laurie Lambot, Bart De Strooper, Andreas Ebneth, Pierre Vanderhaeghen, Mark Fiers, Lorna Omodho, Selina Wray, Jean Pierre Brion, Kunie Ando, Jérôme Bonnefont, An Snellinx, Nikky Corthout
Publikováno v:
Neuron. 93:1066-1081.e8
Human pluripotent stem cells (PSCs) provide a unique entry to study species-specific aspects of human disorders such as Alzheimer's disease (AD). However, in vitro culture of neurons deprives them of their natural environment. Here we transplanted hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc5a436a8bc0f24b08321b5e5eb523e
https://doi.org/10.1016/j.neuron.2017.02.001
https://doi.org/10.1016/j.neuron.2017.02.001