Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Elke Roeb"'
Autor:
Verena von Bülow, Maryam Schneider, Dorothee Dreizler, Lena Russ, Anne Baier, Nicola Buss, Jakob Lichtenberger, Lukas Härle, Heike Müller, Annette Tschuschner, Gabriele Schramm, Jörn Pons-Kühnemann, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 107-117 (2024)
Background & Aims: Schistosomiasis is one of the most prominent parasite-induced infectious diseases, affecting more than 250 million people. Schistosoma mansoni causes metabolic exhaustion and a strong redox imbalance in the liver, causing parenchym
Externí odkaz:
https://doaj.org/article/03b592b3094a49659ed5de0bf1d43345
Autor:
Heike Müller, Jan K. Straßmann, Anne S. Baier, Verena von Bülow, Frederik Stettler, Maximilian J. Hagen, Fabian P. Schmidt, Annette Tschuschner, Andreas R. Schmid, Daniel Zahner, Kernt Köhler, Jörn Pons-Kühnemann, Daniel Leufkens, Dieter Glebe, Surmeet Kaur, Max F. Möscheid, Simone Haeberlein, Christoph G. Grevelding, Ralf Weiskirchen, Mohamed El-Kassas, Khaled Zalata, Elke Roeb, Martin Roderfeld
Publikováno v:
Cells, Vol 13, Iss 19, p 1643 (2024)
Schistosomiasis affects over 250 million people worldwide, with the highest prevalence at the age of 10–14 years. The influence of the host’s age on the severity of liver damage is unclear. We infected male 8, 14, and 20-week-old mice with S. man
Externí odkaz:
https://doaj.org/article/7fb650e6fac343df8883926123b51846
Autor:
Lena Russ, Verena von Bülow, Sarah Wrobel, Frederik Stettler, Gabriele Schramm, Franco H. Falcone, Christoph G. Grevelding, Martin Roderfeld, Elke Roeb
Publikováno v:
Cells, Vol 13, Iss 18, p 1579 (2024)
Schistosomiasis, a parasitic disease caused by Schistosoma spp., affects more than 250 million people worldwide. S. mansoni in particular affects the gastrointestinal tract and, through its eggs, induces a Th2 immune response leading to granuloma for
Externí odkaz:
https://doaj.org/article/d1c40398bf9f44c1a09e5e41c1422a8c
Autor:
Lukas Härle, Verena von Bülow, Lukas Knedla, Frederik Stettler, Heike Müller, Daniel Zahner, Simone Haeberlein, Anita Windhorst, Annette Tschuschner, Monika Burg-Roderfeld, Kernt Köhler, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Schistosomiasis is a parasitic disease affecting more than 250 million people worldwide. The transcription factor c-Jun, which is induced in S. mansoni infection-associated liver disease, can promote hepatocyte survival but can also trigger
Externí odkaz:
https://doaj.org/article/85d43555af414192a45ae30b4e1cfbfb
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 33 (2023)
The pleiotropic chemokine chemerin is involved in multiple processes in metabolism and inflammation. The present study aimed to elucidate its regulation in morbid obesity and during therapy-induced rapid weight loss. A total of 128 severely obese pat
Externí odkaz:
https://doaj.org/article/28bceef64b3f4986a42890d3a2501d6e
Autor:
Nora Helmrich, Martin Roderfeld, Anne Baier, Anita Windhorst, Diran Herebian, Ertan Mayatepek, Christian Dierkes, Matthias Ocker, Dieter Glebe, Bruno Christ, Yuri Churin, Karuna Irungbam, Elke Roeb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1041-1055 (2022)
Background & Aims: The endocannabinoid system is involved in the modulation of inflammatory, fibrotic, metabolic, and carcinogenesis-associated signaling pathways via cannabinoid receptor (CB)1 and CB2. We hypothesized that the pharmacologic antagoni
Externí odkaz:
https://doaj.org/article/d09d8c8611ec48a3bb15ab6b0b480739
Autor:
Verena von Bülow, Sarah Gindner, Anne Baier, Laura Hehr, Nicola Buss, Lena Russ, Sarah Wrobel, Victoria Wirth, Kuscha Tabatabai, Thomas Quack, Simone Haeberlein, Patrik Kadesch, Stefanie Gerbig, Katja R. Wiedemann, Bernhard Spengler, Annabel Mehl, Gertrud Morlock, Gabriele Schramm, Jörn Pons-Kühnemann, Franco H. Falcone, R. Alan Wilson, Katrin Bankov, Peter Wild, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
JHEP Reports, Vol 5, Iss 2, Pp 100625- (2023)
Background & Aims: Schistosomiasis is a parasitic infection which affects more than 200 million people globally. Schistosome eggs, but not the adult worms, are mainly responsible for schistosomiasis-specific morbidity in the liver. It is unclear if S
Externí odkaz:
https://doaj.org/article/6e842731f44a4fffb93fb0d2ff32541f
Autor:
Marie-Lisa Hülser, Yubin Luo, Klaus Frommer, Rebecca Hasseli, Kernt Köhler, Magnus Diller, Lina Van Nie, Christoph Rummel, Martin Roderfeld, Elke Roeb, Georg Schett, Aline Bozec, Ulf Müller-Ladner, Elena Neumann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage loss and reduced joint function. OA risk factors are age and obesity. Many adipokines are altered by obesity but also OA although systemic adipokine regulation in
Externí odkaz:
https://doaj.org/article/dd5774ebdd814e90ab50873b9494e99b
Autor:
Felix Lehmann, Heiko Slanina, Martin Roderfeld, Elke Roeb, Jonel Trebicka, John Ziebuhr, Wolfram H. Gerlich, Christian G. Schüttler, Bernhard Schlevogt, Dieter Glebe
Publikováno v:
Viruses, Vol 15, Iss 4, p 838 (2023)
Chronic hepatitis B virus (HBV) infection is a global health threat. Mutations in the surface antigen of HBV (HBsAg) may alter its antigenicity, infectivity, and transmissibility. A patient positive for HBV DNA and detectable but low-level HBsAg in p
Externí odkaz:
https://doaj.org/article/6cee633209324ff7a9655f20ecb318ea
Autor:
Yuri Churin, Karuna Irungbam, Christoph S. Imiela, David Schwarz, Hans-Joachim Mollenkopf, Uta Drebber, Margarete Odenthal, Oleg Pak, Magdalena Huber, Dieter Glebe, Martin Roderfeld, Elke Roeb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 383-394 (2021)
Background and Aims: A histopathological hallmark of chronic hepatitis B virus (HBV) infection is the presence of ground glass hepatocytes (GGHs). GGHs are liver cells that exhibit eosinophilic, granular, glassy cytoplasm in light microscopy and are
Externí odkaz:
https://doaj.org/article/5d731b4ed5db4b48a5a43b963f5c152e