Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Elke Niebergall-Roth"'
Autor:
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Sabrina Klingele, Michael Jünger, Christoph Hasslacher, Georg Daeschlein, Lutz Stemler, Ulrich Meyer-Pannwitt, Kristin Schubert, Gerhard Klausmann, Titus Raab, Matthias Goebeler, Korinna Kraft, Jasmina Esterlechner, Hannes M. Schröder, Samar Sadeghi, Seda Ballikaya, Martin Gasser, Ana M. Waaga-Gasser, George F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter-Kochanek, Markus H. Frank, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-25 (2022)
Abstract Background While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid infections, amputations and life-threatening complications, DFUs often respond poorly to standard treatment. GMP-manufactured skin-derived ABCB5+ mese
Externí odkaz:
https://doaj.org/article/4819e8d8b5ba4b6b811f719469da6383
Autor:
Hannes M. Schröder, Elke Niebergall-Roth, Alexandra Norrick, Jasmina Esterlechner, Christoph Ganss, Markus H. Frank, Mark A. Kluth
Publikováno v:
Cells, Vol 12, Iss 13, p 1788 (2023)
Quantitative polymerase chain reaction (qPCR) has emerged as an important bioanalytical method for assessing the pharmacokinetics of human-cell-based medicinal products after xenotransplantation into immunodeficient mice. A particular challenge in bi
Externí odkaz:
https://doaj.org/article/408e81adead745d68d6fb5d66f0f37d6
Autor:
Elke Niebergall-Roth, Kathrin Dieter, Cristina Daniele, Silvia Fluhr, Maria Khokhrina, Ines Silva, Christoph Ganss, Markus H. Frank, Mark A. Kluth
Publikováno v:
Cells, Vol 12, Iss 11, p 1468 (2023)
Recessive dystrophic epidermolysis (RDEB) is a rare, inherited, and currently incurable skin blistering disorder characterized by cyclically recurring wounds coexisting with chronic non-healing wounds. In a recent clinical trial, three intravenous in
Externí odkaz:
https://doaj.org/article/92c2cd883e964b7aa6136f5e6e22d255
Autor:
Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Hannes M. Schröder, Seda Ballikaya, Nicole Stemler, Christoph Ganss, Kathrin Dieter, Ann-Kathrin Dachtler, Patrick Merz, Saadettin Sel, James Chodosh, Claus Cursiefen, Natasha Y. Frank, Gerd U. Auffarth, Bruce Ksander, Markus H. Frank, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-21 (2021)
Abstract Background While therapeutic success of the limbal tissue or cell transplantation to treat severe cases of limbal stem cell (LSC) deficiency (LSCD) strongly depends on the percentage of LSCs within the transplanted cells, prospective LSC enr
Externí odkaz:
https://doaj.org/article/05442d04f1184b4784987718c697fe9b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 66 (2022)
The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing-promoting capacities along with superior homing ability. The ABCB5+ MSCs can b
Externí odkaz:
https://doaj.org/article/e0dbd5f5a80c45dfb1c96b35224fe195
Autor:
Seda Ballikaya, Samar Sadeghi, Elke Niebergall-Roth, Laura Nimtz, Jens Frindert, Alexandra Norrick, Nicole Stemler, Nicole Bauer, Yvonne Rosche, Vanessa Kratzenberg, Julia Pieper, Tina Ficek, Markus H. Frank, Christoph Ganss, Jasmina Esterlechner, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Human dermal mesenchymal stromal cells (MSCs) expressing the ATP-binding cassette (ABC) efflux transporter ABCB5 represent an easily accessible MSC population that, based on preclinical and first-in-human data, holds significant p
Externí odkaz:
https://doaj.org/article/0ff6375b1ba34bbea869d8126b38c98d
Autor:
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Ann-Kathrin Dachtler, Korinna Kraft, Markus Stücker, Georg Daeschlein, Michael Jünger, Tobias Görge, Ulrich Meyer-Pannwitt, Cornelia Erfurt-Berge, Charlotte von Engelhardt, Andreas Klare, Christiane Pfeiffer, Jasmina Esterlechner, Hannes M. Schröder, Martin Gasser, Ana M. Waaga-Gasser, Matthias Goebeler, Seda Ballikaya, Samar Sadeghi, George F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter-Kochanek, Markus H. Frank, Mark A. Kluth
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100067- (2022)
A significant number of chronic venous ulcers (CVUs) fail to heal despite guideline-conform standards of care. Skin-derived ABCB5+ mesenchymal stem cells can dampen the sustained IL-1β‒driven inflammation present in chronic wounds. On the basis of
Externí odkaz:
https://doaj.org/article/30269062a0c04e579251c083a6768869
Autor:
Dimitra Kiritsi, Kathrin Dieter, Elke Niebergall-Roth, Silvia Fluhr, Cristina Daniele, Jasmina Esterlechner, Samar Sadeghi, Seda Ballikaya, Leoni Erdinger, Franziska Schauer, Stella Gewert, Martin Laimer, Johann W. Bauer, Alain Hovnanian, Giovanna Zambruno, May El Hachem, Emmanuelle Bourrat, Maria Papanikolaou, Gabriela Petrof, Sophie Kitzmüller, Christen L. Ebens, Markus H. Frank, Natasha Y. Frank, Christoph Ganss, Anna E. Martinez, John A. McGrath, Jakub Tolar, Mark A. Kluth
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating, and life-threatening inherited skin fragility disorder that comes about due to a lack of functional type VII collagen, for which no effective therapy exists. ABCB5+
Externí odkaz:
https://doaj.org/article/b73355f8e6714783859f9acfbd51109d
Autor:
Kluth, Hannes M. Schröder, Elke Niebergall-Roth, Alexandra Norrick, Jasmina Esterlechner, Christoph Ganss, Markus H. Frank, Mark A.
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1788
Quantitative polymerase chain reaction (qPCR) has emerged as an important bioanalytical method for assessing the pharmacokinetics of human-cell-based medicinal products after xenotransplantation into immunodeficient mice. A particular challenge in bi
Publikováno v:
International journal of molecular sciences. 24(1)
The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing-promoting capacities along with superior homing ability. The ABCB5