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Autor:
Elke K.H. Schweda, Per O.G. Arkhammar, Vera Schultz, Per-Olof Berggren, Lisa Juntti-Berggren, Dominic-Luc Webb, Keith Tornheim
Publikováno v:
Journal of Biological Chemistry. 278:40710-40716
Glucose stimulation of pancreatic beta-cells causes oscillatory influx of Ca2+, leading to pulsatile insulin secretion. We have proposed that this is due to oscillations of glycolysis and the ATP/ADP ratio, which modulate the activity of ATP-sensitiv