Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elke Hengstschläger-Ottnad"'
Publikováno v:
Oncogene. 18:843-848
The transcription factors c-Myc and E2F-1 have been shown to harbour both mitogenic and apoptotic properties. Both factors have been implicated in the regulation of the transition from the G1 phase to the S phase in the mammalian cell cycle. However,
Autor:
Katja Braun, Thomas Soucek, Angelina Miloloza, Elke Hengstschläger-Ottnad, Markus Hengstschläger
Publikováno v:
Mutation Research/Reviews in Mutation Research. 436:1-9
In the mammalian cell cycle, the transition from the G1 phase to S phase, in which DNA replication occurs, is dependent on tight cell size control and has been shown to be regulated by the cyclin-dependent kinases (Cdks) 2, 3, 4 and 6. Activities of
Autor:
Wolfgang J. Schneider, Johannes Nimpf, Sabine Novak, Jan Bauer, Walter Stockinger, Elke Hengstschläger-Ottnad, Andrew Matus, Manfred Hüttinger, Hans Lassmann
Publikováno v:
Journal of Biological Chemistry. 273:32213-32221
LR7/8B is a member of the low density lipoprotein receptor gene family that is specifically synthesized in the brain. Here we have functionally expressed in 293 cells the splice variant harboring eight ligand binding repeats (LR8B). As assessed by co
Autor:
Elke Hengstschläger-Ottnad, Markus Hengstschläger, Gerhard Bernaschek, Thomas Soucek, Oliver Pusch
Publikováno v:
DNA and Cell Biology. 16:737-747
Although a remarkable number of genes has been identified that are either activated or repressed via c-Myc, only few of them obviously contribute to Myc's biological effect--the induction of proliferation. We found that in logarithmically growing cel
Autor:
Thomas Soucek, Markus Hengstschläger, Peter D. Adams, Oliver Pusch, Elke Hengstschläger-Ottnad
Publikováno v:
Oncogene. 14:2251-2257
The transcription factor E2F activates genes required for S phase, such as cyclin E and cyclin A. We show that, contrary to long term effects of E2F-1 overexpression, short ectopic overexpression of this transcription factor in logarithmically growin
Autor:
Edgar Wawra, Oliver Pusch, Gerhard Bernaschek, Peter F. Ambros, Markus Hengstschläger, Elke Hengstschläger-Ottnad
Publikováno v:
DNA and Cell Biology. 15:41-51
Homozygous deletions of the tumor suppressor gene p16/MTS1 were reported in a wide variety of tumors and tumor cell lines. Its product inhibits the phosphorylation of the retinoblastoma protein (pRb) by CDK4 and CDK6. Because phosphorylation of pRb i
Publikováno v:
Journal of Biological Chemistry. 270:26139-26145
Rapidly growing oocytes in the laying hen are, in addition to the liver, targets of the so-called “reverse cholesterol transport” (RCT) (Vieira, P. M., Vieira, A. V., Sanders, E. J., Steyrer, E., Nimpf, J., and Schneider, W. J.(1995) J. Lipid Res
Autor:
Elke Hengstschläger-Ottnad, Yuan Zhong, Robert G. Elkin, Wolfgang J. Schneider, Shawn S. Donkin
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 143(3)
As a result of a hereditable point mutation in the oocyte very low density lipoprotein (VLDL) receptor, sexually mature restricted ovulator (RO) female chickens (Gallus gallus), first described as a non-laying strain, exhibit endogenous hyperlipidemi
Autor:
Markus Hengstschläger, Marion Kubista, David M. Rodman, Margit Rosner, Angelina Miloloza, Elke Hengstschläger-Ottnad
Publikováno v:
Mutation research. 488(3)
Two genes, TSC1 and TSC2, have been shown to be responsible for tuberous sclerosis (TSC). The detection of loss of heterozygosity of TSC1 or TSC2 in hamartomas, the growths characteristically occurring in TSC patients, suggested a tumor suppressor fu
Autor:
Gerhard Bernaschek, Markus Hengstschläger, Oliver Pusch, Thomas Soucek, Elke Hengstschläger-Ottnad
Publikováno v:
BioTechniques. 23(2)