Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Elke Dworatzek"'
Autor:
Shokoufeh Mahmoodzadeh, Katharina Koch, Cindy Schriever, Jingman Xu, Maria Steinecker, Joachim Leber, Elke Dworatzek, Bettina Purfürst, Severine Kunz, Deborah Recchia, Monica Canepari, Arnd Heuser, Silvia Di Francescantonio, Ingo Morano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1249-1265 (2021)
Abstract Background Aging is associated with a progressive reduction in cellular function leading to poor health and loss of physical performance. Mitochondrial dysfunction is one of the hallmarks of aging; hence, interventions targeting mitochondria
Externí odkaz:
https://doaj.org/article/89015aa050f4436080df6d7a85fa6664
Autor:
Shokoufeh Mahmoodzadeh, Elke Dworatzek
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Numerous epidemiological, clinical, and animal studies showed that cardiac function and manifestation of cardiovascular diseases (CVDs) are different between males and females. The underlying reasons for these sex differences are definitely multifact
Externí odkaz:
https://doaj.org/article/a6343eb447404c258ad96223973bacd6
Autor:
Melanie Kny, Kitti D Csályi, Kristin Klaeske, Katharina Busch, Alexander M Meyer, Anne M Merks, Katrin Darm, Elke Dworatzek, Daniela Fliegner, Istvan Baczko, Vera Regitz-Zagrosek, Christian Butter, Friedrich C Luft, Daniela Panáková, Jens Fielitz
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216987 (2019)
Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy is accompanied by an increase in myocyte surface area, which requires a proportional increase in the number of cell-cell a
Externí odkaz:
https://doaj.org/article/41e8fcd5039d43ddaa4957a1470dd2df
Autor:
Gabriela L, Santos, Alisa N, DeGrave, Abdul, Rehman, Sara, Al Disi, Kristin, Xhaxho, Helen, Schröder, Guobin, Bao, Tim, Meyer, Malte, Tiburcy, Elke, Dworatzek, Wolfram-Hubertus, Zimmermann, Susanne, Lutz
Publikováno v:
Biomaterials advances 139, 213041 (2022). doi:10.1016/j.bioadv.2022.213041
Tissue engineering with human cardiac fibroblasts (CF) allows identifying novel mechanisms and anti-fibrotic drugs in the context of cardiac fibrosis. However, substantial knowledge on the influences of the used materials and tissue geometries on tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fea840c808a5040ce8b1b46289bdf89
https://publica.fraunhofer.de/handle/publica/436278
https://publica.fraunhofer.de/handle/publica/436278
Publikováno v:
Expert Opinion on Investigational Drugs. 29:881-891
Skeletal muscle wasting is a frequent clinical problem encountered in patients with chronic diseases. Increased levels of inflammatory markers play a role in the imbalance between muscle protein synthesis and degradation. Although testosterone has lo
Autor:
Stephan von Haehling, Christoph Birner, Elke Dworatzek, Stefan Frantz, Kristian Hellenkamp, Carsten W. Israel, Tibor Kempf, Hermann H. Klein, Christoph Knosalla, Ulrich Laufs, Philip Raake, Rolf Wachter, Gerd Hasenfuss
Publikováno v:
Nature reviews. Cardiology. 19(5)
Patients with heart failure are at a higher risk of cardiovascular events compared with the general population, particularly during domestic or international travel. Patients with heart failure should adhere to specific recommendations during travel
Autor:
Daniela Fliegner, Cindy Schriever, Elke Dworatzek, Shokoufeh Mahmoodzadeh, Susanne Lutz, Yuet-Kin Leung, Lisa Kramer, Wolfram-Hubertus Zimmermann, Gabriela L. Santos, Shuk-Mei Ho, Kana Kusumoto, Vera Regitz-Zagrosek
Publikováno v:
Cardiovascular research. 115(2)
AimsSex differences in cardiac fibrosis point to the regulatory role of 17β-Estradiol (E2) in cardiac fibroblasts (CF). We, therefore, asked whether male and female CF in rodent and human models are differentially susceptible to E2, and whether this
Publikováno v:
PROTEOMICS - Clinical Applications. 10:84-91
Purpose Aging has severe implications for tissue damage and is a major risk factor for disease. However, the effects of aging on cardiac extracellular matrix (ECM) components in individuals free of cardiovascular disease are incompletely understood.
Autor:
Holger Summer, Georgios Kararigas, Christoph Knosalla, Stefan Golz, Roland Hetzer, Elke Dworatzek, István Baczkó, George Petrov, Tabea Marie Schulze, Vera Regitz-Zagrosek
Publikováno v:
European Journal of Heart Failure. 16:1160-1167
Aims Women with aortic stenosis develop a more concentric form of LV hypertrophy than men. However, the molecular factors underlying sex differences in LV remodelling are incompletely understood. We took an unbiased approach to identify sex-specific
Autor:
Anna Maria D'Ursi, Virginia M. Miller, Walter Malorni, Claudine Junien, Gregor Majdic, Elisa Giannetta, Susanna M. Hofmann, Georgios Kararigas, Ute Seeland, Rebecca M. Reynolds, Cara Tannenbaum, Christin Mieth, Thomas C. Carpenter, Renée Ventura-Clapier, Sandra Brunelleschi, Elke Dworatzek, Vera Regitz-Zagrosek, Flavia Franconi, Miyuki Katai, Karolina Kublickiene, Marek Glezerman, Hiroaki Shimokawa, Jeanette Erdmann, Jean-François Arnal, Inke R. König
Publikováno v:
Cardiovasc. Res. 113, 711-724 (2017)
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2017, 113 (7), pp.711-724. ⟨10.1093/cvr/cvx066⟩
Ventura-Clapier, R, Dworatzek, E, Seeland, U, Kararigas, G, Arnal, J F, Brunelleschi, S, Carpenter, T, Erdmann, J, Franconi, F, Giannetta, E, Glezerman, M, Hofmann, S, Junien, C, Katai, M, Kublickiene, K, König, I R, Majdic, G, Malorni, W, Mieth, C, Miller, V, Reynolds, R, Shimokawa, H, Tannenbaum, C, D`Ursi, A M & Regitz-Zagrosek, V 2017, ' Sex in basic research – Concepts in the cardiovascular field ', Cardiovascular Research, vol. 113, no. 7 . https://doi.org/10.1093/cvr/cvx066
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2017, 113 (7), pp.711-724. ⟨10.1093/cvr/cvx066⟩
Ventura-Clapier, R, Dworatzek, E, Seeland, U, Kararigas, G, Arnal, J F, Brunelleschi, S, Carpenter, T, Erdmann, J, Franconi, F, Giannetta, E, Glezerman, M, Hofmann, S, Junien, C, Katai, M, Kublickiene, K, König, I R, Majdic, G, Malorni, W, Mieth, C, Miller, V, Reynolds, R, Shimokawa, H, Tannenbaum, C, D`Ursi, A M & Regitz-Zagrosek, V 2017, ' Sex in basic research – Concepts in the cardiovascular field ', Cardiovascular Research, vol. 113, no. 7 . https://doi.org/10.1093/cvr/cvx066
Article en libre accès; Women and men, female and male animals and cells are biologically different, and acknowledgement of this fact is critical to advancing medicine. However, incorporating concepts of sex-specific analysis in basic research is la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abacbbce8ee0c2cbdbe736a837e0cce
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51080
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51080