Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Elke A Ober"'
Autor:
Iris A Unterweger, Julie Klepstad, Edouard Hannezo, Pia R Lundegaard, Ala Trusina, Elke A Ober
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002315 (2023)
To meet the physiological demands of the body, organs need to establish a functional tissue architecture and adequate size as the embryo develops to adulthood. In the liver, uni- and bipotent progenitor differentiation into hepatocytes and biliary ep
Externí odkaz:
https://doaj.org/article/f3dfa61ca94e4f20962d72c9cdc2a81c
Autor:
Kimberly J Morgan, Karen Doggett, Fansuo Geng, Stephen Mieruszynski, Lachlan Whitehead, Kelly A Smith, Benjamin M Hogan, Cas Simons, Gregory J Baillie, Ramyar Molania, Anthony T Papenfuss, Thomas E Hall, Elke A Ober, Didier YR Stainier, Zhiyuan Gong, Joan K Heath
Publikováno v:
eLife, Vol 12 (2023)
The nucleoporin (NUP) ELYS, encoded by AHCTF1, is a large multifunctional protein with essential roles in nuclear pore assembly and mitosis. Using both larval and adult zebrafish models of hepatocellular carcinoma (HCC), in which the expression of an
Externí odkaz:
https://doaj.org/article/00504a5ab43345eda6eb322958fe33b8
Autor:
Yeliz Boglev, Andrew P Badrock, Andrew J Trotter, Qian Du, Elsbeth J Richardson, Adam C Parslow, Sebastian J Markmiller, Nathan E Hall, Tanya A de Jong-Curtain, Annie Y Ng, Heather Verkade, Elke A Ober, Holly A Field, Donghun Shin, Chong H Shin, Katherine M Hannan, Ross D Hannan, Richard B Pearson, Seok-Hyung Kim, Kevin C Ess, Graham J Lieschke, Didier Y R Stainier, Joan K Heath
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003279 (2013)
Ribosome biogenesis underpins cell growth and division. Disruptions in ribosome biogenesis and translation initiation are deleterious to development and underlie a spectrum of diseases known collectively as ribosomopathies. Here, we describe a novel
Externí odkaz:
https://doaj.org/article/f2b587b2488b4beba385b93b524c7da4
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Here, the authors present a method based on optical tweezers to measure mechanical properties of cells inside living zebrafish embryos. The measurement reveals spatiotemporally distinct mechanical properties, linking cell mechanics and morphogenesis.
Externí odkaz:
https://doaj.org/article/a3e2574f9be5415a86b02e3eb67f049f
Autor:
M. Ilcim Thestrup, Sara Caviglia, Jordi Cayuso, Ronja L. S. Heyne, Racha Ahmad, Wolfgang Hofmeister, Letizia Satriano, David G. Wilkinson, Jesper B. Andersen, Elke A. Ober
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promo
Externí odkaz:
https://doaj.org/article/d573b8c9777949828bdc150f56bc1b0b
Autor:
Elizabeth M. G. Ambrosio, Charlotte S. L. Bailey, Iris A. Unterweger, Jens B. Christensen, Marcel P. Bruchez, Pia R. Lundegaard, Elke A. Ober
The liver restores its mass and architecture after injury. Yet, investigating morphogenetic cell behaviours and signals that repair tissue architecture at high spatiotemporal resolution remains challenging. We developed LiverZap, a tuneable chemoptog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ac4bfece0b83efd8e0ca3d06408ee4
https://doi.org/10.1101/2023.03.13.531762
https://doi.org/10.1101/2023.03.13.531762
Autor:
Ditte Gry Ellman, Ibrahim Mohamad Slaiman, Sabrina Bech Mathiesen, Kristian Skriver Andersen, Wolfgang Hofmeister, Elke Annette Ober, Ditte Caroline Andersen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5865 (2021)
Ischemic heart disease is one of the leading causes of deaths worldwide. A major hindrance to resolving this challenge lies in the mammalian hearts inability to regenerate after injury. In contrast, zebrafish retain a regenerative capacity of the hea
Externí odkaz:
https://doaj.org/article/392dee24558c4263959d4ed82f836a32
Autor:
Kimberly J Morgan, Karen Doggett, Fansuo Geng, Stephen Mieruszynski, Lachlan Whitehead, Kelly A Smith, Benjamin M Hogan, Cas Simons, Gregory J Baillie, Ramyar Molania, Anthony T Papenfuss, Thomas E Hall, Elke A Ober, Didier YR Stainier, Zhiyuan Gong, Joan K Heath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d726efe8c4dce834f4f87b8c0b905c
https://doi.org/10.7554/elife.73407.sa2
https://doi.org/10.7554/elife.73407.sa2
Autor:
Jordi Cayuso, Letizia Satriano, Elke A. Ober, David G. Wilkinson, Sara Caviglia, Ronja L.S. Heyne, Jesper B. Andersen, Racha Ahmad, Wolfgang Hofmeister, M Ilcim Thestrup
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Thestrup, M I, Caviglia, S, Cayuso, J, Heyne, R L S, Ahmad, R, Hofmeister, W, Satriano, L, Wilkinson, D G, Andersen, J B & Ober, E A 2019, ' A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation ', Nature Communications, vol. 10, 5220 . https://doi.org/10.1038/s41467-019-13149-7
Thestrup, M I, Caviglia, S, Cayuso, J, Heyne, R L S, Ahmad, R, Hofmeister, W, Satriano, L, Wilkinson, D G, Andersen, J B & Ober, E A 2019, ' A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation ', Nature Communications, vol. 10, no. 1, 5220 . https://doi.org/10.1038/s41467-019-13149-7
Nature Communications
Thestrup, M I, Caviglia, S, Cayuso, J, Heyne, R L S, Ahmad, R, Hofmeister, W, Satriano, L, Wilkinson, D G, Andersen, J B & Ober, E A 2019, ' A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation ', Nature Communications, vol. 10, 5220 . https://doi.org/10.1038/s41467-019-13149-7
Thestrup, M I, Caviglia, S, Cayuso, J, Heyne, R L S, Ahmad, R, Hofmeister, W, Satriano, L, Wilkinson, D G, Andersen, J B & Ober, E A 2019, ' A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation ', Nature Communications, vol. 10, no. 1, 5220 . https://doi.org/10.1038/s41467-019-13149-7
Nature Communications
The hepatopancreatic ductal (HPD) system connects the intrahepatic and intrapancreatic ducts to the intestine and ensures the afferent transport of the bile and pancreatic enzymes. Yet the molecular and cellular mechanisms controlling their different
Autor:
Fan-Suo Geng, Karen Doggett, Lachlan Whitehead, Gregory J. Baillie, Benjamin M. Hogan, Zhiyuan Gong, Elke A. Ober, Joan K. Heath, Kelly A. Smith, Anthony T. Papenfuss, Cas Simons, Thomas E. Hall, Didier Y.R. Stainier, Kimberly J. Morgan, Ramyar Molania
The nucleoporin ELYS, encoded by AHCTF1, is a large multifunctional protein with essential roles in nuclear pore assembly and mitosis. Using a zebrafish model of hepatocellular carcinoma, in which the expression of an inducible mutant kras transgene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99e8230623be4b40fd41c6c877207b6
https://doi.org/10.1101/2021.08.25.457580
https://doi.org/10.1101/2021.08.25.457580