Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elke Günther"'
Autor:
Sven Schönecker, Udo Kraushaar, D. Haspel, Elke Günther, Gisela Drews, Peter Krippeit-Drews, Martina Düfer, Thomas Pfeiffer
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 462:835-840
The membrane potential (V (m)) of beta-cells oscillates at glucose concentrations between ~6 and 25 mM, i.e. burst phases with action potentials alternate with silent interburst phases generating so-called slow waves. The slow waves drive oscillation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3fe3c495afff4b4bd303e5d3644b6e
https://doi.org/10.1007/s00424-011-1029-z
https://doi.org/10.1007/s00424-011-1029-z
Publikováno v:
Drug Safety. 27:763-772
Drug-induced QT interval prolongation is now a major concern in safety pharmacology. Regulatory authorities such as the US FDA and the European Medicines Agency require in vitro testing of all drug candidates against the potential risk for QT interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4328e12a8c74be6840015bbbb049c40d
https://doi.org/10.2165/00002018-200427110-00002
https://doi.org/10.2165/00002018-200427110-00002
Publikováno v:
Assay and drug development technologies. 2(5)
Cardiac safety pharmacology focuses mostly on the drug-induced prolongation of the QT interval in the electrocardiogram. A prolonged QT interval is an important indicator for an increased risk of severe ventricular arrhythmia. Guidelines demand safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4460b5c5db8d1040eb5dfbd98773328
https://pubmed.ncbi.nlm.nih.gov/15671648
https://pubmed.ncbi.nlm.nih.gov/15671648
Autor:
Andreas Elepfandt, Elke Günther, Andrea Fleig, Burkhardt Traub, Michaela Hainich, Susanne Hepperle, Ilse Eistetter
Publikováno v:
The Journal of experimental biology. 203(Pt 23)
Hearing threshold and frequency discrimination for underwater sound were measured in the clawed frog Xenopus laevis by means of conditioning. A go/no go discrimination procedure was used in which the test tone was presented concurrently with a wave o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d5fb25239a7ae90b7c01a168b9376d
https://pubmed.ncbi.nlm.nih.gov/11060223
https://pubmed.ncbi.nlm.nih.gov/11060223
Publikováno v:
Assay & Drug Development Technologies; Oct2004, Vol. 2 Issue 5, p507-514, 8p
Publikováno v:
Epilepsia. 20:431-436
Summary: In 36 epileptic children treated with primidone alone or in combination with additional anticonvulsants, salivary drug levels were compared in resting (I) and in flow-stimulated (II) saliva and were related to the corresponding serum levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c36bfbbba01c883632522c1ec544b2
https://doi.org/10.1111/j.1528-1157.1979.tb04824.x
https://doi.org/10.1111/j.1528-1157.1979.tb04824.x
Publikováno v:
European journal of pediatrics. 126(1-2)
In 17 children on carbamazepine medication alone and 15 children on combined drug regimens, carbamazepine levels were determined in paired samples of serum and mixed saliva by enzyme immunoassay. Carbamazepine levels in serum and saliva were highly c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c149a178e582c498d369b0c834263875
https://pubmed.ncbi.nlm.nih.gov/902662
https://pubmed.ncbi.nlm.nih.gov/902662
Autor:
H. Bartels, Elke Günther
Publikováno v:
Pediatric Research. 13:74-74
To test the value of measuring salivary levels to predict serum levels in anticonvulsive treated children, serum ph and pr levels were compared to salivary levels before and after stimulation of salivary flow with chewing gum. The drug levels were me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a09694adcd684fa24c726d84b8ec80cd
https://doi.org/10.1203/00006450-197901000-00029
https://doi.org/10.1203/00006450-197901000-00029