Sennoside-induced Secretion is Not Caused by Changes in Mucosal Permeability or Na+,K+-ATPase Activity

Autor: Elke Leng‐Peschlow

Publikováno v: Journal of Pharmacy and Pharmacology. 45:951-954

The effect of sennosides (50 mg kg−1) on the rat colon in-situ was studied 6 h after oral treatment when the laxative effect was maximal. In a second experiment, rhein (4 × 10−3 m), an active sennoside metabolite, was administered into the lumen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89af6c581da545c5e1c9f3b66939a898
https://doi.org/10.1111/j.2042-7158.1993.tb05633.x

[ALTERNATIVES IN THE TREATMENT OF CHRONIC CONSTIPATION]

Autor: Elke, Leng Peschlow

Publikováno v: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru. 19(4)

This article briefly reviews epidemiological, patophysiological and definition aspects of chronic constipation. Additionally, treatment of constipation regarding to general an specific measures, including several types of laxatives and presenting the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3b9cc8b149699ee7df3eb2109797cb5
https://pubmed.ncbi.nlm.nih.gov/12181580

Subject Index, Vol. 47 (suppl 1), 1993

Autor: W. Voderholzer, I. Winblad, E.G. Hahn, P.G. Flanagan, B. Schneider, T. Frieling, K. Geboes, A. Van Damme, Chantal Dupuy, Joseph Lemli, P. Koistinen, A.P. Passmore, M.G. Scott, A. Schirgi-Degen, C. Rupprecht, P. Sjöberg, S. Müller-Lissner, A. Lydén-Sokolowski, S.A. Müller-Lissner, Masao Hattori, Stefan A. Müller-Lissner, G. Nijs, Klaus Witthohn, J. Siemers, C. Stoker, Wilson Davies, J.D. Wood, M. Schemann, Kyoichi Kobashi, B. Ueberschaer, Tove Lynn Farbrot, G. Baretton, K. Ewe, Jan Schuurkes, N.W. Read, Wolf Grimminger, Kunhua Fan, J. Kusche, O. Kinnunen, Tone Junker, Karl Egil Malterud, A.G. Klauser, J.E. Lennard-Jones, K.P.J. Geboes, H.G. Miltenburger, Angelo A. Izzo, C. Spiessens, E. Beubler, G. Müller, R.D.E. Rumsey, A. Heidemann, Amnon Sonnenberg, Karel Geboes, G. Franz, K.P. Odenthal, G. Krumbiegel, T. Yagi, Martin Lipkin, E. Leng-Peschlow, A. Nilsson, Elke Leng-Pescklow, G. Nusko, Nicola Mascolo, K. Yamauchi, Reidar Bredo Sund, H.U. Schulz, R.L. Rudolph, S. Kuwano, Anne Elisabeth Huse, Elke Leng-Peschlow, Peter de Witte, J. Salokannel, Lionel Bueno, Werner Lang, P.E. Squires, Astrid D. Müller, Kan Yang, Ann Meulemans, Teruaki Akao, C.-P. Siegers, Jean Fioramonti, Francesco Capasso, Tsuneo Namba, Giuseppina Autore, A.G. Press, Ulrich Mengs, U. Mengs, Giulia Di Carlo, P. De Witte

Publikováno v: Pharmacology. 47:262-262

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ca145cee1a9c3dc4411bd4cf9e97b9e
https://doi.org/10.1159/000139870

Inhibition of intestinal water and electrolyte absorption by senna derivatives in rats

Autor: Elke Leng‐Peschlow

Publikováno v: Journal of Pharmacy and Pharmacology. 32:330-335

Three intestinal segments were simultaneously perfused with Tyrode solution in the anaesthetized rat using a perfusion rate of 12 ml h−1. Dried purified senna extract containing 60% Ca-sennosides A + B (I) administered with the perfusion fluid had

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b38cd96d0d68bf6b8e7a2fbaf0de13
https://doi.org/10.1111/j.2042-7158.1980.tb12930.x

Effects of Sennosides A + B and Bisacodyl on Rat Large Intestine

Autor: Elke Leng-Peschlow

Publikováno v: Pharmacology. 38:310-318

Oral and intracecal administration of bisacodyl or sennosides A + B (10-100 mg/kg each) to rats induced a similar quantity of soft feces within 24 h and a similar acceleration of large intestinal transit time, but in each case bisacodyl had a prolong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a465ed3b3d64cac7be3af7864dd88f
https://doi.org/10.1159/000138551