Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis

Autor: El Menshawe, Shahira F., Shalaby, Khaled, Elkomy, Mohammed H., Aboud, Heba M., Ahmed, Yasmin M., Abdelmeged, Abdelmeged A., Elkarmalawy, Marwa, Abou Alazayem, Mahmoud A., El Sisi, Amani M.

Publikováno v: In International Journal of Pharmaceutics: X June 2024 7

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Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis.

Autor: El Menshawe SF; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt., Shalaby K; Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia., Elkomy MH; Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia., Aboud HM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt., Ahmed YM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt., Abdelmeged AA; Department of Pharmaceutics, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt., Elkarmalawy M; Department of Pharmaceutics and Drug Manufacturing, Faculty of Pharmacy, Modern University for Technology and Information, Cairo, Egypt., Abou Alazayem MA; Department of Pharmaceutics, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt., El Sisi AM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Publikováno v: International journal of pharmaceutics: X [Int J Pharm X] 2023 Dec 20; Vol. 7, pp. 100225. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2024).